ATE480764T1 - Verfahren und vorrichtung für 3-d-bildgebung von innerhalb von proben befindlichen lichtquellen - Google Patents

Verfahren und vorrichtung für 3-d-bildgebung von innerhalb von proben befindlichen lichtquellen

Info

Publication number
ATE480764T1
ATE480764T1 AT03764754T AT03764754T ATE480764T1 AT E480764 T1 ATE480764 T1 AT E480764T1 AT 03764754 T AT03764754 T AT 03764754T AT 03764754 T AT03764754 T AT 03764754T AT E480764 T1 ATE480764 T1 AT E480764T1
Authority
AT
Austria
Prior art keywords
light sources
sample
tissue
imaging
samples
Prior art date
Application number
AT03764754T
Other languages
German (de)
English (en)
Inventor
Daniel Stearns
Bradley Rice
Michael Cable
Original Assignee
Xenogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xenogen Corp filed Critical Xenogen Corp
Application granted granted Critical
Publication of ATE480764T1 publication Critical patent/ATE480764T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/763—Bioluminescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/24—Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B11/00—Measuring arrangements characterised by the use of optical techniques
    • G01B11/24—Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures
    • G01B11/25—Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures by projecting a pattern, e.g. one or more lines, moiré fringes on the object
    • G01B11/2518—Projection by scanning of the object
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02001—Interferometers characterised by controlling or generating intrinsic radiation properties
    • G01B9/02002—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies
    • G01B9/02004—Interferometers characterised by controlling or generating intrinsic radiation properties using two or more frequencies using frequency scans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02015—Interferometers characterised by the beam path configuration
    • G01B9/02029—Combination with non-interferometric systems, i.e. for measuring the object
    • G01B9/0203—With imaging systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01B—MEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00—Measuring instruments characterised by the use of optical techniques
    • G01B9/02—Interferometers
    • G01B9/02041—Interferometers characterised by particular imaging or detection techniques
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N13/00—Stereoscopic video systems; Multi-view video systems; Details thereof
    • H04N13/20—Image signal generators
    • H04N13/204—Image signal generators using stereoscopic image cameras
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N13/00—Stereoscopic video systems; Multi-view video systems; Details thereof
    • H04N13/20—Image signal generators
    • H04N13/204—Image signal generators using stereoscopic image cameras
    • H04N13/25—Image signal generators using stereoscopic image cameras using two or more image sensors with different characteristics other than in their location or field of view, e.g. having different resolutions or colour pickup characteristics; using image signals from one sensor to control the characteristics of another sensor
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N13/00—Stereoscopic video systems; Multi-view video systems; Details thereof
    • H04N13/20—Image signal generators
    • H04N13/271—Image signal generators wherein the generated image signals comprise depth maps or disparity maps

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Plasma & Fusion (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Eye Examination Apparatus (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT03764754T 2002-07-16 2003-07-15 Verfahren und vorrichtung für 3-d-bildgebung von innerhalb von proben befindlichen lichtquellen ATE480764T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39535702P 2002-07-16 2002-07-16
US39645802P 2002-07-16 2002-07-16
US39631302P 2002-07-16 2002-07-16
US10/606,976 US7616985B2 (en) 2002-07-16 2003-06-25 Method and apparatus for 3-D imaging of internal light sources
PCT/US2003/022273 WO2004008123A1 (en) 2002-07-16 2003-07-15 Method and apparatus for 3-d imaging of internal light sources

Publications (1)

Publication Number Publication Date
ATE480764T1 true ATE480764T1 (de) 2010-09-15

Family

ID=30119337

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03764754T ATE480764T1 (de) 2002-07-16 2003-07-15 Verfahren und vorrichtung für 3-d-bildgebung von innerhalb von proben befindlichen lichtquellen

Country Status (10)

Country Link
US (5) US7616985B2 (enExample)
EP (1) EP1521959B1 (enExample)
JP (1) JP2006513400A (enExample)
CN (1) CN1678900A (enExample)
AT (1) ATE480764T1 (enExample)
AU (1) AU2003249299A1 (enExample)
CA (1) CA2492483A1 (enExample)
DE (1) DE60334098D1 (enExample)
IL (1) IL166262A0 (enExample)
WO (1) WO2004008123A1 (enExample)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7383076B2 (en) * 2000-11-27 2008-06-03 The General Hospital Corporation Fluorescence-mediated molecular tomography
ATE336717T1 (de) 2001-05-17 2006-09-15 Xenogen Corp Verfahren und vorrichtung zur feststellung von zieltiefe, helligkeit und grösse in einer körperregion
US7298415B2 (en) 2001-07-13 2007-11-20 Xenogen Corporation Structured light imaging apparatus
US7474398B2 (en) * 2002-02-22 2009-01-06 Xenogen Corporation Illumination system for an imaging apparatus with low profile output device
US6922246B2 (en) * 2002-02-22 2005-07-26 Xenogen Corporation Bottom fluorescence illumination assembly for an imaging apparatus
US7474399B2 (en) * 2002-02-22 2009-01-06 Xenogen Corporation Dual illumination system for an imaging apparatus and method
EP2410315B1 (en) 2002-06-04 2020-04-01 Visen Medical, Inc. Imaging volumes with arbitrary geometries in contact and non-contact tomography
US7599731B2 (en) * 2002-07-16 2009-10-06 Xenogen Corporation Fluorescent light tomography
US7616985B2 (en) * 2002-07-16 2009-11-10 Xenogen Corporation Method and apparatus for 3-D imaging of internal light sources
EP1593095B1 (en) 2003-02-05 2019-04-17 The General Hospital Corporation Method and system for free space optical tomography of diffuse media
US8090431B2 (en) * 2003-03-10 2012-01-03 University Of Iowa Research Foundation Systems and methods for bioluminescent computed tomographic reconstruction
US7190991B2 (en) 2003-07-01 2007-03-13 Xenogen Corporation Multi-mode internal imaging
WO2005057488A2 (en) * 2003-12-03 2005-06-23 Anticancer, Inc. Modular system for multi-color, whole body fluorescence imaging
EP1765172B1 (en) * 2004-06-18 2013-04-24 Elmaleh, David R. Intravascular imaging device and uses thereof
EP1816503B1 (en) * 2004-11-26 2017-11-08 Olympus Corporation Luminescent sample imaging method
US7477931B2 (en) 2004-12-06 2009-01-13 Cambridge Research & Instruments, Inc. Systems and methods for in-vivo and optical imaging and measurement
US8044996B2 (en) * 2005-05-11 2011-10-25 Xenogen Corporation Surface construction using combined photographic and structured light information
DE102005045907B4 (de) * 2005-09-26 2014-05-22 Siemens Aktiengesellschaft Vorrichtung zur Darstellung eines einen Fluoreszenzfarbstoff enthaltenden Gewebes
WO2007042641A1 (fr) * 2005-10-10 2007-04-19 Biospace Lab Dispositif et procede d’imagerie en luminescence
FR2891924B1 (fr) * 2005-10-10 2007-12-28 Biospace Mesures Dispositif et procede d'imagerie en luminescence
JP2007183425A (ja) 2006-01-06 2007-07-19 Olympus Corp 観察装置
EP2021774B1 (en) * 2006-05-15 2016-07-27 Xenogen Corporation A system comprising a dual illumination system and an imaging apparatus and method using said system
EP1865430A3 (en) * 2006-06-05 2009-09-23 Cambridge Research & Instrumentation, Inc. Monte Carlo simulation using GPU units on personal computers
US10335038B2 (en) 2006-08-24 2019-07-02 Xenogen Corporation Spectral unmixing for in-vivo imaging
US10775308B2 (en) * 2006-08-24 2020-09-15 Xenogen Corporation Apparatus and methods for determining optical tissue properties
CA2620949C (en) * 2006-12-22 2015-08-04 New Art Advanced Research Technologies Inc. Method and apparatus for optical image reconstruction using contour determination
WO2008124832A1 (en) * 2007-04-10 2008-10-16 University Of Rochester Structured illumination for imaging of stationary and non-stationary, fluorescent and non-flourescent objects
FR2920874B1 (fr) * 2007-09-10 2010-08-20 Biospace Lab Installation et procede d'imagerie en luminescence
US8031924B2 (en) * 2007-11-30 2011-10-04 General Electric Company Methods and systems for removing autofluorescence from images
EP2067432A3 (en) * 2007-12-05 2012-12-26 FUJIFILM Corporation Image processing system, image processing method, and program
WO2009081498A1 (ja) * 2007-12-26 2009-07-02 Shimadzu Corporation 生体画像取得装置
JP5239472B2 (ja) * 2008-04-11 2013-07-17 株式会社島津製作所 蛍光イメージング装置
FR2930420B1 (fr) * 2008-04-24 2010-06-04 Centre Nat Rech Scient Procede et systeme non invasif de detection et d'evaluation de l'activite electrophysiologique neuronale
WO2009139058A1 (ja) 2008-05-15 2009-11-19 株式会社島津製作所 生体画像撮影装置
CN102144154B (zh) * 2008-10-01 2015-04-22 东卡莱罗纳大学 用结构入射光测定混浊介质光学特征的方法与系统
US8401619B2 (en) * 2009-09-22 2013-03-19 Visen Medical, Inc. Systems and methods for virtual index-matching of diffusive media
DE102010007396B4 (de) * 2010-02-03 2013-10-02 Carl Zeiss Oim Gmbh Verfahren und Vorrichtung zum optischen Inspizieren eines Prüflings mit einer zumindest teilweise reflektierenden Oberfläche
US9693728B2 (en) 2010-06-29 2017-07-04 Lucidux, Llc Systems and methods for measuring mechanical properties of deformable materials
US20120041302A1 (en) * 2010-08-16 2012-02-16 Caliper Life Sciences, Inc. Portable imaging subject cartridge
WO2012030973A2 (en) 2010-09-01 2012-03-08 Spectral Instruments Imaging, LLC Methods and systems for producing visible light and x-ray image data
JP2013538350A (ja) 2010-09-01 2013-10-10 スペクトラル・インストゥルメンツ・イメージング・エルエルシー 励起光源組立体
CN101947103B (zh) * 2010-09-20 2012-03-28 西安电子科技大学 全光学生物发光断层成像方法
US8729502B1 (en) 2010-10-28 2014-05-20 The Research Foundation For The State University Of New York Simultaneous, single-detector fluorescence detection of multiple analytes with frequency-specific lock-in detection
CN102831642B (zh) * 2011-01-27 2014-04-23 深圳泰山在线科技有限公司 一种物体表面重建的系统和方法
CN102867328B (zh) * 2011-01-27 2014-04-23 深圳泰山在线科技有限公司 一种物体表面重建的系统
CN102867329B (zh) * 2011-01-27 2014-04-23 深圳泰山在线科技有限公司 一种物体表面重建的系统和方法
US9314218B2 (en) 2011-06-20 2016-04-19 Caliper Life Sciences, Inc. Integrated microtomography and optical imaging systems
CN102319058B (zh) * 2011-09-09 2013-03-06 清华大学 一种融合荧光、核素和x光三模态的小动物成像系统
US20150078642A1 (en) * 2012-04-24 2015-03-19 The General Hospital Corporation Method and system for non-invasive quantification of biologial sample physiology using a series of images
CN104853669B (zh) * 2012-10-15 2017-07-21 文森医学公司 具有荧光及生物发光源的交叉形态加权特征的漫射介质成像的系统、方法及设备
US10169909B2 (en) * 2014-08-07 2019-01-01 Pixar Generating a volumetric projection for an object
KR101610148B1 (ko) * 2014-11-17 2016-04-08 현대자동차 주식회사 차체 검사 시스템 및 방법
US10595794B2 (en) 2015-07-09 2020-03-24 Auburn University Devices and methods for facilitating imaging of rotating animals, specimens, or imaging phantoms
JP6617978B2 (ja) * 2017-04-07 2019-12-11 株式会社島津製作所 光イメージング装置
US11200698B2 (en) 2017-06-01 2021-12-14 Germaine Laboratories, Inc. Devices and systems for data-based analysis of objects
US10275681B2 (en) 2017-06-01 2019-04-30 Germaine Laboratories, Inc. Devices and systems for image-based analysis of test media
US9983117B1 (en) * 2017-06-01 2018-05-29 Germaine Laboratories, Inc. Devices and systems for image-based analysis of test media
CA3095410A1 (en) 2018-03-30 2019-10-03 Perkinelmer Health Sciences, Inc. Systems and methods for 3d reconstruction of anatomical organs and inclusions using short-wave infrared (swir) projection tomography
EP3811055A4 (en) * 2018-06-19 2022-08-10 Becton, Dickinson and Company VARIABLE MULTIPLEXING SWITCHES FOR SENSOR NETWORKS, SYSTEMS AND METHODS OF USE THEREOF
CN109856092B (zh) * 2018-11-22 2021-08-31 上海无线电设备研究所 一种海洋荧光探测半解析蒙特卡罗模拟方法
US11889048B2 (en) * 2020-08-18 2024-01-30 Sony Group Corporation Electronic device and method for scanning and reconstructing deformable objects
FR3131376B1 (fr) * 2021-12-29 2023-11-10 Commissariat Energie Atomique Procédé d’estimation d’une distribution spatiale tridimensionnelle de fluorescence, à l’intérieur d’un objet.

Family Cites Families (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2910178C2 (de) 1979-03-15 1981-02-26 Georg Menshen & Co Kg, 5950 Finnentrop Originalitäts-Schraubverschluß für Flaschen u.dgl
JPS60256443A (ja) 1984-05-31 1985-12-18 オムロン株式会社 画像計測装置
US4761071A (en) * 1984-11-06 1988-08-02 Baron William S Apparatus and method for determining corneal and scleral topography
US4687352A (en) 1984-12-29 1987-08-18 Brother Kogyo Kabushiki Kaisha Printer with an image reader
US4772453A (en) 1985-03-01 1988-09-20 Lisenbee Wayne F Luminiscence measurement arrangement
US4687325A (en) 1985-03-28 1987-08-18 General Electric Company Three-dimensional range camera
US5205291A (en) * 1988-11-08 1993-04-27 Health Research, Inc. In vivo fluorescence photometer
JP2970967B2 (ja) 1991-11-20 1999-11-02 浜松ホトニクス株式会社 蛍光性プローブ試薬を用いた細胞内イオン濃度測定法
FR2684092B1 (fr) * 1991-11-21 1994-03-04 Pechiney Recherche Procede de preparation de carbures metalliques a grande surface specifique a partir de mousses de carbone activees.
US5242441A (en) 1992-02-24 1993-09-07 Boaz Avitall Deflectable catheter with rotatable tip electrode
JP3107914B2 (ja) 1992-07-20 2000-11-13 浜松ホトニクス株式会社 散乱吸収体内部の吸収情報計測装置及び方法
US5452723A (en) 1992-07-24 1995-09-26 Massachusetts Institute Of Technology Calibrated spectrographic imaging
US5746210A (en) 1993-02-26 1998-05-05 David A. Benaron Device and method for detection, localization, and characterization of inhomogeneities in turbid media
DE4338758C2 (de) 1992-11-13 2001-08-09 Scimed Life Systems Inc Katheteranordnung
US5334193A (en) 1992-11-13 1994-08-02 American Cardiac Ablation Co., Inc. Fluid cooled ablation catheter
FR2699227B1 (fr) * 1992-12-16 1995-01-13 Snecma Ensemble monobloc de post-combustion d'une turbine à gaz.
US5673701A (en) 1994-10-07 1997-10-07 Non Invasive Technology, Inc. Optical techniques for examination of biological tissue
JPH09504964A (ja) 1993-10-29 1997-05-20 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア 拡散光を用いた対象物撮像
US5414258A (en) 1993-11-22 1995-05-09 Angstrom Technologies, Inc. Apparatus and method for calibration of fluorescence detectors
US6217847B1 (en) 1994-07-01 2001-04-17 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
US5650135A (en) 1994-07-01 1997-07-22 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive localization of a light-emitting conjugate in a mammal
IL110538A0 (en) 1994-08-02 1994-11-11 Oren Aharon Tomographic imaging system
US5672881A (en) 1994-09-14 1997-09-30 Glyko, Inc. Charge-coupled device imaging apparatus
US5840572A (en) 1994-10-11 1998-11-24 United States Of America As Represented By The Secretary Of The Navy Bioluminescent bioassay system
US5705807A (en) 1994-10-24 1998-01-06 Nissan Motor Co., Ltd. Photo detecting apparatus for detecting reflected light from an object and excluding an external light componet from the reflected light
JP3433534B2 (ja) 1994-11-07 2003-08-04 浜松ホトニクス株式会社 散乱吸収体内の散乱特性・吸収特性の測定方法及び装置
AU4594796A (en) 1994-11-25 1996-06-19 Yuriy Alexandrov System and method for diagnosis of living tissue diseases
JP2675532B2 (ja) 1994-12-20 1997-11-12 株式会社バイオセンサー研究所 化学発光測定装置
US5594253A (en) 1994-12-28 1997-01-14 Lockheed Missiles And Space Company, Inc. Hybrid luminescent device for imaging of ionizing and penetrating radiation
US5636299A (en) 1994-12-28 1997-06-03 Lockheed Missiles & Space Company, Inc. Hybrid luminescent device and method for imaging penetrating radiation
US5919140A (en) 1995-02-21 1999-07-06 Massachusetts Institute Of Technology Optical imaging using time gated scattered light
WO1996036273A2 (en) 1995-05-16 1996-11-21 The United States Of America, Represented By The Secretary Of The Air Force System and method for enhanced visualization of subcutaneous structures
US5865754A (en) * 1995-08-24 1999-02-02 Purdue Research Foundation Office Of Technology Transfer Fluorescence imaging system and method
JP2879003B2 (ja) 1995-11-16 1999-04-05 株式会社生体光情報研究所 画像計測装置
JPH11506839A (ja) 1995-12-22 1999-06-15 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 混濁媒体中の対象を局部化する装置
US5835617A (en) 1996-01-18 1998-11-10 Hamamatsu Photonics K.K. Optical computer tomographic apparatus and image reconstruction method using optical computer tomography
US5738101A (en) 1996-01-18 1998-04-14 The Regents Of The University Of California Optical imaging through turbid media with a degenerate four-wave mixing correlation time gate
IL117241A (en) 1996-02-23 2000-09-28 Talia Technology Ltd Three dimensional imaging apparatus and a method for use thereof
US6108576A (en) 1996-03-18 2000-08-22 The Research Foundation Of City College Of New York Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media
US8349602B1 (en) 1996-04-19 2013-01-08 Xenogen Corporation Biodetectors targeted to specific ligands
US5867250A (en) 1996-05-03 1999-02-02 Baron; William S. Apparatus and method for optically mapping front and back surface topographies of an object
JP3442220B2 (ja) 1996-05-15 2003-09-02 シスメックス株式会社 光散乱媒体中物体の可視化光学システム
US5864633A (en) 1996-05-17 1999-01-26 Therma-Wave, Inc. Method and apparatus for optical data analysis
US6026173A (en) 1997-07-05 2000-02-15 Svenson; Robert H. Electromagnetic imaging and therapeutic (EMIT) systems
EP0910791B1 (en) 1996-07-10 2010-09-08 Perkinelmer Singapore PTE Ltd. Improved imaging system for fluorescence assays
JP3844815B2 (ja) 1996-08-30 2006-11-15 浜松ホトニクス株式会社 散乱体の吸収情報計測方法及び装置
US5812310A (en) 1996-10-16 1998-09-22 Applied Precision, Inc. Orthogonal high accuracy microscope stage
AU5507798A (en) * 1996-11-29 1998-06-22 Imaging Diagnostic Systems, Inc. Detector array for use in a laser imaging apparatus
GB9626825D0 (en) 1996-12-24 1997-02-12 Crampton Stephen J Avatar kiosk
US5963658A (en) 1997-01-27 1999-10-05 University Of North Carolina Method and apparatus for detecting an abnormality within a host medium
AU6320798A (en) 1997-02-07 1998-08-26 Prudue Research Foundation Imaging of light scattering tissues with fluorescent contrast agents
US6208886B1 (en) 1997-04-04 2001-03-27 The Research Foundation Of City College Of New York Non-linear optical tomography of turbid media
US5943129A (en) 1997-08-07 1999-08-24 Cambridge Research & Instrumentation Inc. Fluorescence imaging system
US6069698A (en) 1997-08-28 2000-05-30 Olympus Optical Co., Ltd. Optical imaging apparatus which radiates a low coherence light beam onto a test object, receives optical information from light scattered by the object, and constructs therefrom a cross-sectional image of the object
ES2137879B1 (es) 1997-12-02 2000-08-16 Francisco Soria Melguizo S A Sistema analizador de imagenes producidas por reacciones bacterianas.
JP3771364B2 (ja) 1997-12-12 2006-04-26 浜松ホトニクス株式会社 光ｃｔ装置及び画像再構成方法
EP1040366B1 (de) 1997-12-23 2003-10-08 Siemens Aktiengesellschaft Verfahren und vorrichtung zur aufnahme eines dreidimensionalen abstandsbildes
US6364829B1 (en) 1999-01-26 2002-04-02 Newton Laboratories, Inc. Autofluorescence imaging system for endoscopy
US6205347B1 (en) 1998-02-27 2001-03-20 Picker International, Inc. Separate and combined multi-modality diagnostic imaging system
WO1999058930A1 (en) 1998-05-14 1999-11-18 Metacreations Corporation Structured-light, triangulation-based three-dimensional digitizer
US6252623B1 (en) 1998-05-15 2001-06-26 3Dmetrics, Incorporated Three dimensional imaging system
US6242743B1 (en) 1998-08-11 2001-06-05 Mosaic Imaging Technology, Inc. Non-orbiting tomographic imaging system
WO2000017643A2 (en) 1998-09-18 2000-03-30 Cellomics, Inc. A system for cell-based screening
US6615061B1 (en) 1998-11-23 2003-09-02 Abbott Laboratories Optical sensor having a selectable sampling distance for determination of analytes
JP3585753B2 (ja) 1998-12-15 2004-11-04 富士写真フイルム株式会社 撮影システム
US6175407B1 (en) 1998-12-17 2001-01-16 Identix Incorporated Apparatus and method for optically imaging features on the surface of a hand
EP1141359B1 (en) 1998-12-17 2006-10-04 Xenogen Corporation Non-invasive evaluation of physiological response in a mammal
US6205353B1 (en) * 1998-12-22 2001-03-20 Research Foundation Of Cuny Time-resolved optical backscattering tomographic image reconstruction in scattering turbid media
US6610503B1 (en) 1999-03-17 2003-08-26 Xenogen Corporation Animal models for predicting sepsis mortality
WO2000055882A1 (en) 1999-03-18 2000-09-21 Cambridge Research & Instrumentation Inc. High-efficiency multiple probe imaging system
US6264610B1 (en) 1999-05-05 2001-07-24 The University Of Connecticut Combined ultrasound and near infrared diffused light imaging system
US6415051B1 (en) 1999-06-24 2002-07-02 Geometrix, Inc. Generating 3-D models using a manually operated structured light source
US6219566B1 (en) 1999-07-13 2001-04-17 Photonics Research Ontario Method of measuring concentration of luminescent materials in turbid media
WO2001011343A1 (en) 1999-08-06 2001-02-15 Cambridge Research & Instrumentation Inc. Spectral imaging system
US6750964B2 (en) 1999-08-06 2004-06-15 Cambridge Research And Instrumentation, Inc. Spectral imaging methods and systems
AU2589500A (en) 1999-09-03 2001-04-10 Xenogen Corporation Targeting constructs and transgenic animals produced therewith
US6381302B1 (en) 2000-07-05 2002-04-30 Canon Kabushiki Kaisha Computer assisted 2D adjustment of stereo X-ray images
US6710770B2 (en) 2000-02-11 2004-03-23 Canesta, Inc. Quasi-three-dimensional method and apparatus to detect and localize interaction of user-object and virtual transfer device
US7581191B2 (en) 1999-11-15 2009-08-25 Xenogen Corporation Graphical user interface for 3-D in-vivo imaging
JP3553451B2 (ja) 2000-02-18 2004-08-11 独立行政法人 科学技術振興機構 光干渉断層像観測装置
US6775567B2 (en) 2000-02-25 2004-08-10 Xenogen Corporation Imaging apparatus
US20010033376A1 (en) 2000-02-25 2001-10-25 Cambridge Reseach & Instrumentation Inc. Automatic G-factor calibration
US6377353B1 (en) 2000-03-07 2002-04-23 Pheno Imaging, Inc. Three-dimensional measuring system for animals using structured light
JP3999437B2 (ja) 2000-03-10 2007-10-31 富士フイルム株式会社 光断層画像化装置
US6429943B1 (en) 2000-03-29 2002-08-06 Therma-Wave, Inc. Critical dimension analysis with simultaneous multiple angle of incidence measurements
EP1154224A1 (en) 2000-05-09 2001-11-14 Fuji Photo Film Co., Ltd. Optical coherence tomography apparatus using optical-waveguide structure which reduces pulse width of low-coherence light
US6748259B1 (en) 2000-06-15 2004-06-08 Spectros Corporation Optical imaging of induced signals in vivo under ambient light conditions
US6693710B1 (en) 2000-06-16 2004-02-17 Cambridge Research & Instrumentation Inc. Polarization imaging system
SE519734C2 (sv) 2000-07-07 2003-04-01 Axis Ab Bildförändringsanordning för en bildalstrande apparat samt metod och digitalkamera till densamma
US6597931B1 (en) 2000-09-18 2003-07-22 Photonify Technologies, Inc. System and method for absolute oxygen saturation
US6394965B1 (en) 2000-08-15 2002-05-28 Carbon Medical Technologies, Inc. Tissue marking using biocompatible microparticles
JP2002095663A (ja) 2000-09-26 2002-04-02 Fuji Photo Film Co Ltd センチネルリンパ節光断層画像取得方法および装置
US7383076B2 (en) 2000-11-27 2008-06-03 The General Hospital Corporation Fluorescence-mediated molecular tomography
US6615063B1 (en) 2000-11-27 2003-09-02 The General Hospital Corporation Fluorescence-mediated molecular tomography
US20020083265A1 (en) * 2000-12-26 2002-06-27 Brough Farrell Lynn Methods for increasing cache capacity
ATE336717T1 (de) 2001-05-17 2006-09-15 Xenogen Corp Verfahren und vorrichtung zur feststellung von zieltiefe, helligkeit und grösse in einer körperregion
US6919919B2 (en) 2002-02-06 2005-07-19 Xenogen Corporation Light calibration device for use in low level light imaging systems
US7298415B2 (en) 2001-07-13 2007-11-20 Xenogen Corporation Structured light imaging apparatus
US7113217B2 (en) * 2001-07-13 2006-09-26 Xenogen Corporation Multi-view imaging apparatus
US6775349B2 (en) 2001-10-23 2004-08-10 Washington Univ. In St. Louis System and method for scanning near-field optical tomography
US7474399B2 (en) 2002-02-22 2009-01-06 Xenogen Corporation Dual illumination system for an imaging apparatus and method
US6924893B2 (en) 2002-05-13 2005-08-02 Marine Biological Laboratory Enhancing polarized light microscopy
EP2410315B1 (en) 2002-06-04 2020-04-01 Visen Medical, Inc. Imaging volumes with arbitrary geometries in contact and non-contact tomography
US6628747B1 (en) 2002-06-21 2003-09-30 Washington University In St. Louis System and method for dual-beam internal reflection tomography
US7536644B2 (en) 2002-06-27 2009-05-19 Siemens Medical Solutions Usa, Inc. Method and system for facilitating selection of stored medical images
US6618463B1 (en) * 2002-07-09 2003-09-09 Washington University System and method for single-beam internal reflection tomography
US7616985B2 (en) 2002-07-16 2009-11-10 Xenogen Corporation Method and apparatus for 3-D imaging of internal light sources
US20040027659A1 (en) 2002-08-08 2004-02-12 Messerschmidt Robert G. Sample holder
US20040085536A1 (en) * 2002-11-01 2004-05-06 Schotland John Carl Tomography system and method using nonlinear reconstruction of scattered radiation
EP1593095B1 (en) 2003-02-05 2019-04-17 The General Hospital Corporation Method and system for free space optical tomography of diffuse media
US7034303B2 (en) 2003-06-27 2006-04-25 Washington University System and method of image reconstruction for optical tomography with limited data
DE102004030550A1 (de) * 2004-06-24 2006-01-19 Siemens Ag Bildgebendes Tomographiegerät mit zumindest zwei unter Systemwinkel angeordneten Aufnahmesystemen und Verfahren für ein derartiges Tomographiegerät zur Bestimmung der Systemwinkel der Aufnahmesysteme
US7477931B2 (en) 2004-12-06 2009-01-13 Cambridge Research & Instruments, Inc. Systems and methods for in-vivo and optical imaging and measurement
ATE527619T1 (de) 2005-01-27 2011-10-15 Cambridge Res & Instrumentation Inc Klassifizierung der bildeigenschaften
US8044996B2 (en) 2005-05-11 2011-10-25 Xenogen Corporation Surface construction using combined photographic and structured light information
WO2008052006A2 (en) * 2006-10-23 2008-05-02 Xenogen Corporation Apparatus and methods for fluorescence guided surgery

Also Published As

Publication number Publication date
AU2003249299A1 (en) 2004-02-02
US7797034B2 (en) 2010-09-14
US8909326B2 (en) 2014-12-09
WO2004008123A1 (en) 2004-01-22
EP1521959A1 (en) 2005-04-13
CN1678900A (zh) 2005-10-05
DE60334098D1 (de) 2010-10-21
US7616985B2 (en) 2009-11-10
US7603167B2 (en) 2009-10-13
CA2492483A1 (en) 2004-01-22
US20100022872A1 (en) 2010-01-28
EP1521959B1 (en) 2010-09-08
IL166262A0 (en) 2006-01-15
US20050201614A1 (en) 2005-09-15
US20040021771A1 (en) 2004-02-05
US20080018899A1 (en) 2008-01-24
US20110090316A1 (en) 2011-04-21
US7860549B2 (en) 2010-12-28
JP2006513400A (ja) 2006-04-20

Similar Documents

Publication Publication Date Title
ATE480764T1 (de) Verfahren und vorrichtung für 3-d-bildgebung von innerhalb von proben befindlichen lichtquellen
Marcelino et al. Modulation of light-enhancement to symbiotic algae by light-scattering in corals and evolutionary trends in bleaching
Swain et al. Relating coral skeletal structures at different length scales to growth, light availability to Symbiodinium, and thermal bleaching
CN101600387A (zh) 用于对不透明介质的内部进行光学成像的方法、用于重建不透明介质内部的图像的方法、用于对不透明介质的内部成像的设备、医疗图像采集设备以及用于所述方法和设备中的计算机程序产品
Frantz et al. Multi-scattering software part II: experimental validation for the light intensity distribution
Sawosz et al. Method to improve the depth sensitivity of diffuse reflectance measurements to absorption changes in optically turbid medium
Pu et al. Basic optical scattering parameter of the brain and prostate tissues in the spectral range of 400–2400 nm
WO2017167031A1 (zh) 一种利用数学模型计算人皮肤光吸收相关的19个生物学参数的方法
Bertrand et al. Deciphering the chemistry of cultural heritage: targeting material properties by coupling spectral imaging with image analysis
Gomes et al. Paleometry as a key tool to deal with paleobiological and astrobiological issues: some contributions and reflections on the Brazilian fossil record
Li et al. Fourier-transformed infrared spectroscopy study of the ancient ivory tusks from the Sanxingdui site
Marengo et al. Time-gated transillumination of objects in highly scattering media using a subpicosecond optical amplifier
Fawzy et al. Determination of scattering volume fraction and particle size distribution in the superficial layer of a turbid medium by using diffuse reflectance spectroscopy
Shapira et al. Dependency of crossover point on absorption changes in bilayer diffusion reflection measurements
Chernomordik et al. Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination
CN105894537A (zh) 一种发射式光学投影断层成像衰减与散射校正方法
Pu et al. Investigation of scattering coefficients and anisotropy factors of human cancerous and normal prostate tissues using Mie theory
Lu et al. Parallelized Monte Carlo photon transport simulations for arbitrary multi-angle wide-field illumination in optoacoustic imaging
Faber et al. Pathlength distribution of (sub) diffusively reflected light
Krainov et al. Study of contrasting properties of nanoparticles for optical diffuse spectroscopy problems
Phillips et al. Calculation of photon path changes due to scatter in Monte Carlo simulations
Sarkar et al. A stochastic differential equation-based Monte Carlo simulation to model light propagation in dynamic turbid media
Sato et al. Highly sensitive fluorescence microscope system for single biological cell using laser excitation and digital image processing and display
Ducros et al. Fluorescence diffuse optical tomography: A simulation-based study comparing time-resolved and continuous wave reconstructions performances
Peter Comparative study on 3D modelling of breast cancer using Nir-Fdot in COMSOL

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties