ATE479681T1 - Substituierte piperidine - Google Patents

Substituierte piperidine

Info

Publication number
ATE479681T1
ATE479681T1 AT06725445T AT06725445T ATE479681T1 AT E479681 T1 ATE479681 T1 AT E479681T1 AT 06725445 T AT06725445 T AT 06725445T AT 06725445 T AT06725445 T AT 06725445T AT E479681 T1 ATE479681 T1 AT E479681T1
Authority
AT
Austria
Prior art keywords
substituted piperidines
piperidines
substituted
Prior art date
Application number
AT06725445T
Other languages
English (en)
Inventor
Peter Herold
Robert Mah
Vincenzo Tschinke
Christiane Marti
Stefan Stutz
Stjepan Jelakovic
Frank Hollinger
Zenon D Konteatis
Jennifer L Ludington
Michael Quirmbach
Aleksandar Stojanovic
Dirk Behnke
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE479681T1 publication Critical patent/ATE479681T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT06725445T 2005-03-31 2006-03-30 Substituierte piperidine ATE479681T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66655605P 2005-03-31 2005-03-31
US75085305P 2005-12-16 2005-12-16
PCT/EP2006/061197 WO2006103277A2 (en) 2005-03-31 2006-03-30 2 , 4 , 5-substituted piperidines as renin inhibitors

Publications (1)

Publication Number Publication Date
ATE479681T1 true ATE479681T1 (de) 2010-09-15

Family

ID=36586065

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06725445T ATE479681T1 (de) 2005-03-31 2006-03-30 Substituierte piperidine

Country Status (13)

Country Link
US (2) US20100029628A1 (de)
EP (1) EP1863803B1 (de)
JP (2) JP2008534558A (de)
AR (2) AR055756A1 (de)
AT (1) ATE479681T1 (de)
BR (2) BRPI0608758A2 (de)
CA (1) CA2601702A1 (de)
DE (1) DE602006016573D1 (de)
IL (2) IL186130A0 (de)
PL (1) PL1863803T3 (de)
PT (1) PT1863803E (de)
TW (2) TW200716622A (de)
WO (1) WO2006103277A2 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008510755A (ja) 2004-08-25 2008-04-10 アクテリオン ファーマシューティカルズ リミテッド ビシクロノネン誘導体
AR055756A1 (es) * 2005-03-31 2007-09-05 Speedel Experimenta Ag Piperidinas sustituidas; procesos de preparacion y su uso como medicamentos
RU2410374C2 (ru) 2005-05-27 2011-01-27 Актелион Фармасьютикалз Лтд Новые амидные производные пиперидинкарбоновой кислоты
GB0514203D0 (en) 2005-07-11 2005-08-17 Novartis Ag Organic compounds
ES2373792T3 (es) 2006-05-19 2012-02-08 Abbott Laboratories Derivados de alcanos azabicíclicos sustituidos con bicicloheterociclo condensado activos en el snc.
JP2009539806A (ja) * 2006-06-08 2009-11-19 シュペーデル・エクスペリメンタ・アーゲー ２，５−二置換ピペリジン
TW200821303A (en) * 2006-08-08 2008-05-16 Speedel Experimenta Ag Organic compounds
EP1958634A3 (de) * 2007-02-14 2008-09-24 Speedel Experimenta AG Substituierte Piperidine als Inhibitoren von Beta-Secretase, Cathepsin D, Plasmepsin II und/oder HIV-Protease
AR069005A1 (es) * 2007-10-25 2009-12-23 Speedel Experimenta Ag Piperidinas 4,4-disustituidas
AR069145A1 (es) * 2007-11-02 2009-12-30 Speedel Experimenta Ag Piperidinas 4,4- disusutituidas, uso del compuesto en la produccion de un medicamento, un producto farmaceutico en base al compuesto y un metodo de prevencion de enfermedades
JP5484069B2 (ja) 2007-12-19 2014-05-07 大日本住友製薬株式会社 二環性へテロ環誘導体
MX2010008716A (es) * 2008-02-08 2010-10-25 Novartis Ag Piperidinas sustituidas como inhibidores de renina.
KR20100131427A (ko) * 2008-02-08 2010-12-15 노파르티스 아게 레닌 억제제로서의 치환된 피페리딘
MY152042A (en) 2008-05-05 2014-08-15 Actelion Pharmaceuticals Ltd 3,4- substituted piperidine derivatives as renin inhibitors
EP2163245A1 (de) 2008-09-10 2010-03-17 Novartis Ag Renin-Inhibitoren zur Behandlung von Psoriasis
US8389731B2 (en) 2009-05-15 2013-03-05 Northwestern University Chiral pyrrolidine core compounds en route to inhibitors of nitric oxide synthase
KR20120109292A (ko) 2009-06-24 2012-10-08 다이닛본 스미토모 세이야꾸 가부시끼가이샤 Ｎ-치환-시클릭 아미노 유도체
US9623794B2 (en) * 2015-01-09 2017-04-18 J.W. Speaker Corporation Tracking and lighting systems and methods for a vehicle
DE102015013191A1 (de) * 2015-10-10 2017-04-13 Daimler Ag Verfahren zum Betrieb einer Leuchteinheit und Leuchteinheit

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1256326C (zh) * 1995-09-07 2006-05-17 弗·哈夫曼-拉罗切有限公司 治疗心脏和肾功能不全的新型4－(氧烷氧基苯基)－3－氧哌啶化合物
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US6197959B1 (en) * 1999-04-27 2001-03-06 Hoffmann-La Roche Inc. Piperidine derivatives
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors
AR055756A1 (es) * 2005-03-31 2007-09-05 Speedel Experimenta Ag Piperidinas sustituidas; procesos de preparacion y su uso como medicamentos

Also Published As

Publication number Publication date
DE602006016573D1 (de) 2010-10-14
US7687495B2 (en) 2010-03-30
US20100029628A1 (en) 2010-02-04
JP2008201787A (ja) 2008-09-04
PL1863803T3 (pl) 2011-02-28
IL186130A0 (en) 2008-01-20
WO2006103277A2 (en) 2006-10-05
IL189429A0 (en) 2008-06-05
BRPI0608758A2 (pt) 2009-07-07
EP1863803A2 (de) 2007-12-12
AR065188A2 (es) 2009-05-20
CA2601702A1 (en) 2006-10-05
AR055756A1 (es) 2007-09-05
TW200833687A (en) 2008-08-16
PT1863803E (pt) 2010-11-18
WO2006103277A3 (en) 2006-12-28
TW200716622A (en) 2007-05-01
EP1863803B1 (de) 2010-09-01
US20080171748A1 (en) 2008-07-17
JP2008534558A (ja) 2008-08-28
BRPI0621969A2 (pt) 2011-07-19

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