TW200716622A - Substituted piperidines - Google Patents

Substituted piperidines

Info

Publication number
TW200716622A
TW200716622A TW095110894A TW95110894A TW200716622A TW 200716622 A TW200716622 A TW 200716622A TW 095110894 A TW095110894 A TW 095110894A TW 95110894 A TW95110894 A TW 95110894A TW 200716622 A TW200716622 A TW 200716622A
Authority
TW
Taiwan
Prior art keywords
substituted piperidines
explained
compounds
piperidines
detail
Prior art date
Application number
TW095110894A
Other languages
English (en)
Inventor
Peter Herold
Robert Mah
Vincenzo Tschinke
Michael Quirmbachi
Aleksandar Stojanovic
Dirk Behnke
Christiane Marti
Frank Hollinger
Zenon D Konteatis
Jennifer L Ludington
Stefan Stutz
Stjepan Jelakovic
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Publication of TW200716622A publication Critical patent/TW200716622A/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
TW095110894A 2005-03-31 2006-03-29 Substituted piperidines TW200716622A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66655605P 2005-03-31 2005-03-31
US75085305P 2005-12-16 2005-12-16

Publications (1)

Publication Number Publication Date
TW200716622A true TW200716622A (en) 2007-05-01

Family

ID=36586065

Family Applications (2)

Application Number Title Priority Date Filing Date
TW097113173A TW200833687A (en) 2005-03-31 2006-03-29 Substituted piperidines
TW095110894A TW200716622A (en) 2005-03-31 2006-03-29 Substituted piperidines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
TW097113173A TW200833687A (en) 2005-03-31 2006-03-29 Substituted piperidines

Country Status (13)

Country Link
US (2) US20100029628A1 (zh)
EP (1) EP1863803B1 (zh)
JP (2) JP2008534558A (zh)
AR (2) AR055756A1 (zh)
AT (1) ATE479681T1 (zh)
BR (2) BRPI0608758A2 (zh)
CA (1) CA2601702A1 (zh)
DE (1) DE602006016573D1 (zh)
IL (2) IL186130A0 (zh)
PL (1) PL1863803T3 (zh)
PT (1) PT1863803E (zh)
TW (2) TW200833687A (zh)
WO (1) WO2006103277A2 (zh)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101010323B (zh) 2004-08-25 2010-06-16 埃科特莱茵药品有限公司 作为肾素抑制剂的双环壬烯衍生物
TW200833687A (en) * 2005-03-31 2008-08-16 Speedel Experimenta Ag Substituted piperidines
EP1893578A2 (en) 2005-05-27 2008-03-05 Actelion Pharmaceuticals Ltd. Novel piperidine carboxylic acid amide derivatives
GB0514203D0 (en) 2005-07-11 2005-08-17 Novartis Ag Organic compounds
AU2007253950B2 (en) 2006-05-19 2012-05-03 Abbott Laboratories CNS active fused bicycloheterocycle substituted azabicyclic alkane derivatives
CA2660667A1 (en) * 2006-06-08 2007-12-13 Speedel Experimenta Ag 2,5-disubstituted piperidines
TW200821303A (en) * 2006-08-08 2008-05-16 Speedel Experimenta Ag Organic compounds
EP1958634A3 (en) * 2007-02-14 2008-09-24 Speedel Experimenta AG Substituted piperidines as inhibitors of beta-secretase, cathepsin D, plasmepsin II and/or HIV protease
TW200922596A (en) * 2007-10-25 2009-06-01 Speedel Experimenta Ag 4,4-disubstituted piperidines
US20100267713A1 (en) * 2007-11-02 2010-10-21 Peter Herold 4,4-disubstituted piperidines
CN101952280B (zh) 2007-12-19 2014-04-23 大日本住友制药株式会社 双环杂环衍生物
BRPI0907728A2 (pt) 2008-02-08 2015-07-14 Novartis Ag Piperidinas substituídas como inibidores de renina
JP2011511039A (ja) 2008-02-08 2011-04-07 ノバルティス アーゲー レニン阻害剤としての置換ピペリジン
WO2009135299A1 (en) 2008-05-05 2009-11-12 Merck Frosst Canada Ltd. 3, 4 - substituted piperidine derivatives as renin inhibitors
EP2163245A1 (en) 2008-09-10 2010-03-17 Novartis Ag Renin inhibitors for the treatment of psoriasis
US8389731B2 (en) * 2009-05-15 2013-03-05 Northwestern University Chiral pyrrolidine core compounds en route to inhibitors of nitric oxide synthase
AU2010263641A1 (en) 2009-06-24 2012-01-19 Sumitomo Dainippon Pharma Co., Ltd. N-substituted-cyclic amino derivative
AU2016205036B2 (en) * 2015-01-09 2019-12-19 J.W. Speaker Corporation Tracking and lighting systems and methods for a vehicle
DE102015013191A1 (de) * 2015-10-10 2017-04-13 Daimler Ag Verfahren zum Betrieb einer Leuchteinheit und Leuchteinheit

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100384979B1 (ko) * 1995-09-07 2003-10-17 에프. 호프만-라 로슈 아게 심부전증및신부전증치료용의신규한4-(옥시알콕시페닐)-3-옥시-피페리딘
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US6197959B1 (en) * 1999-04-27 2001-03-06 Hoffmann-La Roche Inc. Piperidine derivatives
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors
TW200833687A (en) * 2005-03-31 2008-08-16 Speedel Experimenta Ag Substituted piperidines

Also Published As

Publication number Publication date
EP1863803B1 (en) 2010-09-01
ATE479681T1 (de) 2010-09-15
WO2006103277A3 (en) 2006-12-28
PL1863803T3 (pl) 2011-02-28
JP2008201787A (ja) 2008-09-04
CA2601702A1 (en) 2006-10-05
JP2008534558A (ja) 2008-08-28
US20080171748A1 (en) 2008-07-17
EP1863803A2 (en) 2007-12-12
DE602006016573D1 (de) 2010-10-14
IL189429A0 (en) 2008-06-05
US7687495B2 (en) 2010-03-30
WO2006103277A2 (en) 2006-10-05
BRPI0621969A2 (pt) 2011-07-19
US20100029628A1 (en) 2010-02-04
PT1863803E (pt) 2010-11-18
AR065188A2 (es) 2009-05-20
BRPI0608758A2 (pt) 2009-07-07
TW200833687A (en) 2008-08-16
IL186130A0 (en) 2008-01-20
AR055756A1 (es) 2007-09-05

Similar Documents

Publication Publication Date Title
TW200716622A (en) Substituted piperidines
TW200513461A (en) Organische verbindungen
GEP20094785B (en) Pyrrolopyrazoles, potent kinase inhibitors
WO2006072612A3 (en) Triazolophthalazines as pde2- inhibitors
TW200728277A (en) Bicyclic derivatives as P38 inhibitors
WO2006072615A3 (en) Triazolophthalazines as pde2-inhibitors
NO20075273L (no) Nye forbindelser
TW200637837A (en) Fungicides
TW200704751A (en) Novel materials for organic electroluminescent devices
WO2006061417A3 (en) Macrocyclic quinazole derivatives and their use as mtki
EP1881975B8 (en) N,n-substituted 3-aminopyrrolidine compounds useful as monoamines reuptake inhibitors
WO2009046841A3 (de) Piperidin- und piperazinderivate zur behandlung von tumoren
NO20075275L (no) Nye forbindelser
PL1682530T3 (pl) Podstawione pirolo-indole jako inhibitory PAI-1
TW200706637A (en) Imidazole derivatives and organic electronic device using the same
UA94910C2 (ru) Замещенные глицинамиды с антитромбическим действием и ингибирующим действием на фактор ха
GB0508314D0 (en) Organic compounds
WO2007120333A3 (en) Tetracyclic kinase inhibitors
TW200700358A (en) Organic compounds
MX2010002245A (es) Derivados de ariloxiacetamida bi o triciclicos, saturados e insaturados y su uso como fungicidas.
WO2007000340A3 (en) Bicyclic derivatives as p38 kinase inhibitors
BRPI0518277A2 (pt) pirrol[1,2-d][1,2-4]triazina como inibidores de cinases de terminal n de c-jun (jnk) e p-38 cinases
NO20045025L (no) Nye forbindelser
TW200716130A (en) Purified form of tanaproget
TW200609226A (en) New isobenzoxazinones and their use as ultraviolet light absorbers