ATE478095T1 - Konjugate mit einem für die ed-b-domäne von fibronectin spezifischen antikörper, und deren verwendung zum nachweis und zur behandlung von tumoren - Google Patents

Konjugate mit einem für die ed-b-domäne von fibronectin spezifischen antikörper, und deren verwendung zum nachweis und zur behandlung von tumoren

Info

Publication number
ATE478095T1
ATE478095T1 AT03726977T AT03726977T ATE478095T1 AT E478095 T1 ATE478095 T1 AT E478095T1 AT 03726977 T AT03726977 T AT 03726977T AT 03726977 T AT03726977 T AT 03726977T AT E478095 T1 ATE478095 T1 AT E478095T1
Authority
AT
Austria
Prior art keywords
fibronectin
domain
conjugates
detecting
antibodies specific
Prior art date
Application number
AT03726977T
Other languages
English (en)
Inventor
Christoph-Stephan Hilger
Dietmar Berndorff
Ludger Dinkelborg
Dieter Moosmayer
Giovanni Neri
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Priority claimed from PCT/EP2003/000009 external-priority patent/WO2003055917A2/en
Application granted granted Critical
Publication of ATE478095T1 publication Critical patent/ATE478095T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03726977T 2002-01-03 2003-01-02 Konjugate mit einem für die ed-b-domäne von fibronectin spezifischen antikörper, und deren verwendung zum nachweis und zur behandlung von tumoren ATE478095T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02000315 2002-01-03
US35870202P 2002-02-25 2002-02-25
PCT/EP2003/000009 WO2003055917A2 (en) 2002-01-03 2003-01-02 Conjugates comprising an antibody specific for the ed-b domain of fibronectin and their use for the detection and treatment of tumours

Publications (1)

Publication Number Publication Date
ATE478095T1 true ATE478095T1 (de) 2010-09-15

Family

ID=35976951

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03726977T ATE478095T1 (de) 2002-01-03 2003-01-02 Konjugate mit einem für die ed-b-domäne von fibronectin spezifischen antikörper, und deren verwendung zum nachweis und zur behandlung von tumoren

Country Status (8)

Country Link
KR (2) KR20100077052A (de)
AT (1) ATE478095T1 (de)
DE (1) DE60333820D1 (de)
DK (1) DK1461360T3 (de)
ES (1) ES2346750T3 (de)
PT (1) PT1461360E (de)
SI (1) SI1461360T1 (de)
ZA (1) ZA200406162B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3691771B1 (de) 2017-10-02 2023-08-16 Battelle Energy Alliance, LLC Verfahren und systeme zur elektrochemischen reduktion von kohlendioxid unter verwendung von umschaltbaren polaritätsmaterialien

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI259837B (en) * 1998-05-11 2006-08-11 Eidgenossische Tech Hochscule Specific binding molecules for scintigraphy, conjugates containing them and therapeutic method for treatment of angiogenesis

Also Published As

Publication number Publication date
SI1461360T1 (sl) 2010-12-31
DE60333820D1 (de) 2010-09-30
ES2346750T3 (es) 2010-10-20
ZA200406162B (en) 2005-09-27
KR20040073540A (ko) 2004-08-19
KR20100077052A (ko) 2010-07-06
DK1461360T3 (da) 2010-11-15
KR100998803B1 (ko) 2010-12-06
PT1461360E (pt) 2010-11-23

Similar Documents

Publication Publication Date Title
MXPA04006517A (es) Conjugados que comprenden un anticuerpo especifico para el dominio ed-b de fibronectina y sus usos para la deteccion y tratamiento de tumores.
ATE443260T1 (de) Kontrastmittel und verfahren zum imaging von naaldase oder psma
CY1120924T1 (el) Αντισωματα εναντι-αλφα v βητα 6 και χρησεις αυτων
RS80704A (en) ANTI- av?6.ANTIBODIES
CY1118566T1 (el) Διαγνωση με χρηση ιντερφερονης τυπου 1
TW200626900A (en) Wnt proteins and detection and treatment of cancer
DE60130538D1 (de) Humanisierte antikörper gegen ccr2 und verfahren zur deren verwendung
BRPI0613382A8 (pt) anticorpos isolados, anticorpo monoclonal, célula de hibridoma, método de identificação, método de inibição do crescimento de uma célula, método de tratamento terapêutico, método de determinação da presença de uma proteína, métodos de diagnósticos da presença de tumor
DE69942742D1 (de) Immuntherapeutische zusammensetzung und verfahren zur behandlung von prostatakrebs
NZ594466A (en) Human monoclonal antibodies to protein tyrosine kinase 7 (PTK7) and methods for using anti-PTK7 antibodies
ATE403001T1 (de) Antigenbindungsfragmente die spezifisch krebszellen nachweisen, nukleotide die für diese fragmente kodieren, und deren verwendung zur vorbeugung und zum nachweis von krebs
NO20072721L (no) Polypeptides that bind BR3 and uses thereof
EA200800094A1 (ru) Антитела cd19 и их использование
ATE459653T1 (de) Monoklonale anti-cd71-antikörper und deren verwendung zur behandlung maligner tumorzellen
ATE492563T1 (de) Vollständige humane monoklonale antikörper gegen il-13
SG170793A1 (en) Anti-mn antibodies and methods of using same
DE602005027399D1 (de) Für humane matriptase spezifische bindungsproteine
ATE526037T1 (de) Verfahren zum abtöten von tumorzellen mittels targeting von auf apoptotischen tumorzellen exponierten internen antigenen
ATE412756T1 (de) Verfahren zur krebsdiagnose mittels eines chimärischen toxin
ATE466031T1 (de) Anti-hgf-r-antikörper und deren verwendung
ATE540676T1 (de) Egfr-inhibitoren zur behandlung und diagnose von metastasierendem prostatakrebs
BRPI0407680A (pt) métodos para diagnóstico de cáncer e diminuição de metástase por células cancerosas
MX2021009975A (es) Anticuerpos de cd33 y métodos para usar los mismos para tratar el cáncer.
ATE553127T1 (de) Oligoklonale anti-clusterin-antikörper zur diagnose und vorhersage der aggressivität von tumoren, diagnostisches verfahren und damit in zusammenhang stehende kits
MXPA05011085A (es) Composiciones y metodos relacionados a stop-1.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1461360

Country of ref document: EP

EELV Lapsed due to withdrawal
REZ Deleted due to withdrawal