ATE477267T1 - Methode zur reinigung von proteinen - Google Patents
Methode zur reinigung von proteinenInfo
- Publication number
- ATE477267T1 ATE477267T1 AT00944505T AT00944505T ATE477267T1 AT E477267 T1 ATE477267 T1 AT E477267T1 AT 00944505 T AT00944505 T AT 00944505T AT 00944505 T AT00944505 T AT 00944505T AT E477267 T1 ATE477267 T1 AT E477267T1
- Authority
- AT
- Austria
- Prior art keywords
- iii
- antithrombin
- impurities
- solution
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004411 Antithrombin III Human genes 0.000 abstract 6
- 108090000935 Antithrombin III Proteins 0.000 abstract 6
- 229960005348 antithrombin iii Drugs 0.000 abstract 6
- 239000012535 impurity Substances 0.000 abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 239000012905 visible particle Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8128—Antithrombin III
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902388A SE9902388D0 (sv) | 1999-06-23 | 1999-06-23 | Method for purification of proteins |
| PCT/SE2000/001193 WO2000078792A1 (en) | 1999-06-23 | 2000-06-08 | Method for purification of proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE477267T1 true ATE477267T1 (de) | 2010-08-15 |
Family
ID=20416211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00944505T ATE477267T1 (de) | 1999-06-23 | 2000-06-08 | Methode zur reinigung von proteinen |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1185551B1 (de) |
| JP (1) | JP4521143B2 (de) |
| AT (1) | ATE477267T1 (de) |
| AU (1) | AU776861B2 (de) |
| CA (1) | CA2376986C (de) |
| DE (1) | DE60044812D1 (de) |
| DK (1) | DK1185551T3 (de) |
| ES (1) | ES2349678T3 (de) |
| NO (1) | NO324627B1 (de) |
| NZ (1) | NZ516235A (de) |
| PT (1) | PT1185551E (de) |
| SE (1) | SE9902388D0 (de) |
| WO (1) | WO2000078792A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4651536B2 (ja) * | 2003-04-17 | 2011-03-16 | 田辺三菱製薬株式会社 | 組換えアンチトロンビンの製造方法 |
| EP1685852A1 (de) * | 2005-02-01 | 2006-08-02 | Fondation pour la Recherche Diagnostique | Set von Einwegbeuteln zur Virusinaktivierung von biologischen Fluids |
| US20060223988A1 (en) * | 2005-04-05 | 2006-10-05 | National Research Laboratories, Ltd. | High Resolution Methods and Precipitating Reagents for Isolating Proteins from Proteinaceous Material |
| CN103059129B (zh) * | 2013-01-28 | 2015-02-11 | 贵州泰邦生物制品有限公司 | 制造人抗凝血酶-iii制品的方法 |
| CN111511800B (zh) | 2017-10-30 | 2023-11-28 | 武田药品工业株式会社 | 灭活脂包膜病毒的环境相容性去污剂 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS597693B2 (ja) * | 1978-01-07 | 1984-02-20 | 株式会社ミドリ十字 | 抗トロンビン製剤及びその製法 |
| US4977246A (en) * | 1989-06-06 | 1990-12-11 | Rorer Pharmaceutical Corporation | High recovery process for antihemophilic factor |
| SE9301582D0 (sv) * | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Purification of plasma proteins |
| JPH08109140A (ja) * | 1994-10-12 | 1996-04-30 | Green Cross Corp:The | 高血圧症予防治療剤 |
-
1999
- 1999-06-23 SE SE9902388A patent/SE9902388D0/xx unknown
-
2000
- 2000-06-08 PT PT00944505T patent/PT1185551E/pt unknown
- 2000-06-08 DE DE60044812T patent/DE60044812D1/de not_active Expired - Lifetime
- 2000-06-08 WO PCT/SE2000/001193 patent/WO2000078792A1/en not_active Ceased
- 2000-06-08 CA CA2376986A patent/CA2376986C/en not_active Expired - Fee Related
- 2000-06-08 DK DK00944505.7T patent/DK1185551T3/da active
- 2000-06-08 AU AU58594/00A patent/AU776861B2/en not_active Ceased
- 2000-06-08 AT AT00944505T patent/ATE477267T1/de active
- 2000-06-08 ES ES00944505T patent/ES2349678T3/es not_active Expired - Lifetime
- 2000-06-08 JP JP2001505550A patent/JP4521143B2/ja not_active Expired - Fee Related
- 2000-06-08 EP EP00944505A patent/EP1185551B1/de not_active Expired - Lifetime
- 2000-06-08 NZ NZ516235A patent/NZ516235A/xx not_active IP Right Cessation
-
2001
- 2001-12-18 NO NO20016174A patent/NO324627B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2376986A1 (en) | 2000-12-28 |
| JP4521143B2 (ja) | 2010-08-11 |
| EP1185551B1 (de) | 2010-08-11 |
| AU776861B2 (en) | 2004-09-23 |
| WO2000078792A1 (en) | 2000-12-28 |
| DK1185551T3 (da) | 2010-11-22 |
| NZ516235A (en) | 2004-01-30 |
| NO20016174L (no) | 2002-02-21 |
| PT1185551E (pt) | 2010-11-12 |
| NO324627B1 (no) | 2007-11-26 |
| CA2376986C (en) | 2010-03-16 |
| NO20016174D0 (no) | 2001-12-18 |
| ES2349678T3 (es) | 2011-01-10 |
| JP2003502438A (ja) | 2003-01-21 |
| EP1185551A1 (de) | 2002-03-13 |
| AU5859400A (en) | 2001-01-09 |
| SE9902388D0 (sv) | 1999-06-23 |
| DE60044812D1 (de) | 2010-09-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE452870T1 (de) | (meth)acrylsaeurekristall und verfahren zur herstellung und aufreinigung von waessriger (meth)acrylsaeure | |
| ATE184884T1 (de) | Fibrinogenkonzentrate aus blutplasma, verfahren und anlage für ihre herstellung | |
| IS7533A (is) | Lifrarbólgu C-veirutálmar | |
| EP2519245A4 (de) | Aus einem sojaverarbeitungsstrom isolierte gereinigte kunitz-trypsin-hemmerproteine | |
| JP2001517212A (ja) | カチオン交換クロマトグラフィーによる因子ＶＩＩＩ／ｖＷＦ複合体の精製方法 | |
| DE3686954D1 (de) | Loeslichkeits-, reinigungs- und charakterisierungsverfahren fuer proteine aus unloeslichen proteinaggregaten oder proteinkomplexen und diesbezuegliche praeparate. | |
| ATE477267T1 (de) | Methode zur reinigung von proteinen | |
| ATE432946T1 (de) | Abtrennung von fibrinogen von plasmaproteasen | |
| ATE491463T1 (de) | Verfahren zur herstellung von alpha (2) makroglobulin-antigen-molekül-komplexen | |
| DE69212660D1 (de) | Verfahren zur Reinigung eines hochglykosylierten Proteins | |
| ATE423131T1 (de) | Verfahren zur reinigung von g-csf | |
| ATE178882T1 (de) | Verfahren zur reinigung von diacetylrhein | |
| DE60041067D1 (de) | Verfahren zur herstellung hochreiner nicht toxischer toxinfragmente | |
| EA200200743A1 (ru) | Рекомбинантное ослабление вируса репродуктивного и респираторного синдрома свиней (prrsv) | |
| NO20033860L (no) | Fremgangsmåte for fjernelse av kalsium fra en sulfatopplösning i sinkprosess | |
| ATE297385T1 (de) | Verfahren zur reinigung von 2-chlor-5- chlormethylthiazol | |
| DE59813491D1 (de) | Verfahren zur Herstellung eines eine Hyaluronidase enthaltenden Präparats | |
| RU2003106162A (ru) | Способ получения препарата коллагеназы | |
| JPS60133887A (ja) | エラスタ−ゼの製法 | |
| DE60236114D1 (de) | Zwitterkristall aus menschlicher Papillomavirus-E2-Transaktivierungsdomäne und einem Inhibitor sowie Roentgenstrukturkoordinaten, die die inhibitorbindende Tasche definieren | |
| DE50303744D1 (de) | Verfahren zur reinigung von liponsäure | |
| DE69326233D1 (de) | Leukinferon zubereitung | |
| ATE540974T1 (de) | Reinigung des rekombinanten menschlichen faktors xiii | |
| ATE424406T1 (de) | Verfahren zur trennung von antithrombin-iii isoformen | |
| CA2557686A1 (en) | Highly purified proteinase k |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1185551 Country of ref document: EP |