DE69212660D1 - Verfahren zur Reinigung eines hochglykosylierten Proteins - Google Patents

Verfahren zur Reinigung eines hochglykosylierten Proteins

Info

Publication number
DE69212660D1
DE69212660D1 DE69212660T DE69212660T DE69212660D1 DE 69212660 D1 DE69212660 D1 DE 69212660D1 DE 69212660 T DE69212660 T DE 69212660T DE 69212660 T DE69212660 T DE 69212660T DE 69212660 D1 DE69212660 D1 DE 69212660D1
Authority
DE
Germany
Prior art keywords
purification
highly glycosylated
glycosylated protein
protein
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69212660T
Other languages
English (en)
Other versions
DE69212660T2 (de
Inventor
Hanno Kolbe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Publication of DE69212660D1 publication Critical patent/DE69212660D1/de
Application granted granted Critical
Publication of DE69212660T2 publication Critical patent/DE69212660T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/816—Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69212660T 1991-02-15 1992-02-13 Verfahren zur Reinigung eines hochglykosylierten Proteins Expired - Fee Related DE69212660T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9101830A FR2672895B1 (fr) 1991-02-15 1991-02-15 Procede de purification d'une proteine fortement glycosylee.

Publications (2)

Publication Number Publication Date
DE69212660D1 true DE69212660D1 (de) 1996-09-19
DE69212660T2 DE69212660T2 (de) 1997-03-13

Family

ID=9409766

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69212660T Expired - Fee Related DE69212660T2 (de) 1991-02-15 1992-02-13 Verfahren zur Reinigung eines hochglykosylierten Proteins

Country Status (9)

Country Link
US (1) US5276141A (de)
EP (1) EP0499541B1 (de)
JP (1) JP3376430B2 (de)
AT (1) ATE141283T1 (de)
CA (1) CA2061167C (de)
DE (1) DE69212660T2 (de)
DK (1) DK0499541T3 (de)
ES (1) ES2092067T3 (de)
FR (1) FR2672895B1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5760189A (en) * 1995-06-02 1998-06-02 Genetics Institute, Inc. Protein recovery & purification methods
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
MXPA01013264A (es) * 1999-06-25 2002-06-04 American Cyanamid Co Extracion de proteinas de membrana integral.
WO2001027275A1 (en) * 1999-10-13 2001-04-19 Lexicon Genetics Incorporated Novel human membrane proteins
US7777006B2 (en) * 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
AU2004309177A1 (en) * 2003-12-30 2005-07-14 Bharat Biotech International Limited A process for the preparation and purification of recombinant proteins
WO2008145021A1 (en) * 2007-05-29 2008-12-04 Xiamen University A truncated l1 protein of human papillomavirus 6
US20160130324A1 (en) 2014-10-31 2016-05-12 Shire Human Genetic Therapies, Inc. C1 Inhibitor Fusion Proteins and Uses Thereof
US20180334493A1 (en) 2015-11-19 2018-11-22 Shire Human Genetic Therapies, Inc. Recombinant human c1 esterase inhibitor and uses thereof
CN113453712A (zh) * 2018-12-28 2021-09-28 特兰斯吉恩股份有限公司 M2缺陷型痘病毒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947324A (en) * 1975-04-21 1976-03-30 G. D. Searle And Co. Method for isolating high purity peroxidase
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
EP0213099A3 (de) * 1985-08-23 1989-07-19 Cederroth Nordic Aktiebolag Mittel mit antiphlogistischer, immunstimulierender und zytoprotektiver Wirkung, ihre Herstellung und pharmazeutische Verwendungen
US4798886A (en) * 1986-03-24 1989-01-17 Takeda Chemical Industries, Ltd. Mutual separation of proteins
FR2597344B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.
JPS63216898A (ja) * 1987-01-30 1988-09-09 インターナシヨナル・ミネラルズ・アンド・ケミカル・コーポレイシヨン 希薄水溶液からソマトトロビンを回収する方法
ES2059355T3 (es) * 1987-12-23 1994-11-16 Immuno Ag Proteinas anfipaticas celulares en forma de agregados y procedimiento para la produccion y la purificacion de estas proteinas.
US4992372A (en) * 1989-02-02 1991-02-12 Pokora Alexander R Method for removing impurities from peroxidase solutions
US5101014A (en) * 1989-02-10 1992-03-31 United States Of America Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis

Also Published As

Publication number Publication date
EP0499541B1 (de) 1996-08-14
CA2061167C (fr) 2002-06-11
US5276141A (en) 1994-01-04
CA2061167A1 (fr) 1992-08-16
FR2672895A1 (fr) 1992-08-21
DE69212660T2 (de) 1997-03-13
ATE141283T1 (de) 1996-08-15
JP3376430B2 (ja) 2003-02-10
ES2092067T3 (es) 1996-11-16
JPH04312600A (ja) 1992-11-04
FR2672895B1 (fr) 1995-05-12
EP0499541A1 (de) 1992-08-19
DK0499541T3 (da) 1996-12-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee