ES2092067T3 - Procedimiento de purificacion de una proteina altamente glicosilada. - Google Patents
Procedimiento de purificacion de una proteina altamente glicosilada.Info
- Publication number
- ES2092067T3 ES2092067T3 ES92400381T ES92400381T ES2092067T3 ES 2092067 T3 ES2092067 T3 ES 2092067T3 ES 92400381 T ES92400381 T ES 92400381T ES 92400381 T ES92400381 T ES 92400381T ES 2092067 T3 ES2092067 T3 ES 2092067T3
- Authority
- ES
- Spain
- Prior art keywords
- protein
- purification procedure
- highly
- highly glycosilated
- glycosilated protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/816—Enzyme separation or purification by solubility
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
LA INVENCION PROPONE UN PROCESO PARA PURIFICAR UNA PROTEINA FUERTEMENTE GLICOSILADA A PARTIR DE UNA PREPARACION BRUTA QUE COMPRENDE EL HECHO (I) DE AÑADIR A DICHA PREPARACION UN ION METALICA BIVALENTE EN CANTIDAD SUFICIENTE DE MANERA A FORMAR UNA MEZCLA QUE PRECIPITA Y (II), TRAS LA PRECIPITACION, DE RECOGER DICHA PROTEINA EN EL SUPERNADANTE DE LA MEZCLA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9101830A FR2672895B1 (fr) | 1991-02-15 | 1991-02-15 | Procede de purification d'une proteine fortement glycosylee. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2092067T3 true ES2092067T3 (es) | 1996-11-16 |
Family
ID=9409766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92400381T Expired - Lifetime ES2092067T3 (es) | 1991-02-15 | 1992-02-13 | Procedimiento de purificacion de una proteina altamente glicosilada. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5276141A (es) |
EP (1) | EP0499541B1 (es) |
JP (1) | JP3376430B2 (es) |
AT (1) | ATE141283T1 (es) |
CA (1) | CA2061167C (es) |
DE (1) | DE69212660T2 (es) |
DK (1) | DK0499541T3 (es) |
ES (1) | ES2092067T3 (es) |
FR (1) | FR2672895B1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284874B1 (en) * | 1994-06-17 | 2001-09-04 | Alpha Therapeutic Corporation | Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste |
US5760189A (en) * | 1995-06-02 | 1998-06-02 | Genetics Institute, Inc. | Protein recovery & purification methods |
US5616693A (en) * | 1996-07-01 | 1997-04-01 | Alpha Therapeutic Corporation | Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste |
ES2315234T3 (es) * | 1999-06-25 | 2009-04-01 | Wyeth Holdings Corporation | Extraccion de proteinas de la membrana intrega. |
AU1198701A (en) * | 1999-10-13 | 2001-04-23 | Lexicon Genetics Incorporated | Novel human membrane proteins |
US7777006B2 (en) | 2002-12-31 | 2010-08-17 | Csl Behring L.L.C. | Method for purification of alpha-1-antitrypsin |
AU2004309177A1 (en) * | 2003-12-30 | 2005-07-14 | Bharat Biotech International Limited | A process for the preparation and purification of recombinant proteins |
CN101343315B (zh) * | 2007-05-29 | 2012-06-13 | 厦门大学 | 截短的人乳头瘤病毒6型l1蛋白 |
US20160130324A1 (en) | 2014-10-31 | 2016-05-12 | Shire Human Genetic Therapies, Inc. | C1 Inhibitor Fusion Proteins and Uses Thereof |
BR112018010160A8 (pt) | 2015-11-19 | 2019-02-26 | Shire Human Genetic Therapies | inibidor da c1 esterase humana recombinante e usos do mesmo |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3947324A (en) * | 1975-04-21 | 1976-03-30 | G. D. Searle And Co. | Method for isolating high purity peroxidase |
JPS6098988A (ja) * | 1983-11-01 | 1985-06-01 | Chemo Sero Therapeut Res Inst | Lpf−haの精製法 |
EP0213099A3 (de) * | 1985-08-23 | 1989-07-19 | Cederroth Nordic Aktiebolag | Mittel mit antiphlogistischer, immunstimulierender und zytoprotektiver Wirkung, ihre Herstellung und pharmazeutische Verwendungen |
US4798886A (en) * | 1986-03-24 | 1989-01-17 | Takeda Chemical Industries, Ltd. | Mutual separation of proteins |
FR2597344B1 (fr) * | 1986-04-16 | 1989-06-23 | Merieux Inst | Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire. |
DD270466A5 (de) * | 1987-01-30 | 1989-08-02 | �������������@��������@�K@���������@����Kk�� | Verfahren zur rueckgewinnung von somatropinen aus verduennten waessrigen loesungen |
ATE95188T1 (de) * | 1987-12-23 | 1993-10-15 | Immuno Ag | Zellulaere amphipatische proteine in aggregierten formen und verfahren zur herstellung und reinigung diese proteine. |
US4992372A (en) * | 1989-02-02 | 1991-02-12 | Pokora Alexander R | Method for removing impurities from peroxidase solutions |
US5101014A (en) * | 1989-02-10 | 1992-03-31 | United States Of America | Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis |
-
1991
- 1991-02-15 FR FR9101830A patent/FR2672895B1/fr not_active Expired - Fee Related
-
1992
- 1992-02-13 DE DE69212660T patent/DE69212660T2/de not_active Expired - Fee Related
- 1992-02-13 ES ES92400381T patent/ES2092067T3/es not_active Expired - Lifetime
- 1992-02-13 DK DK92400381.7T patent/DK0499541T3/da active
- 1992-02-13 AT AT92400381T patent/ATE141283T1/de not_active IP Right Cessation
- 1992-02-13 CA CA002061167A patent/CA2061167C/fr not_active Expired - Fee Related
- 1992-02-13 EP EP92400381A patent/EP0499541B1/fr not_active Expired - Lifetime
- 1992-02-14 JP JP02794092A patent/JP3376430B2/ja not_active Expired - Fee Related
- 1992-02-14 US US07/835,392 patent/US5276141A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69212660D1 (de) | 1996-09-19 |
EP0499541B1 (fr) | 1996-08-14 |
DE69212660T2 (de) | 1997-03-13 |
EP0499541A1 (fr) | 1992-08-19 |
US5276141A (en) | 1994-01-04 |
JPH04312600A (ja) | 1992-11-04 |
FR2672895B1 (fr) | 1995-05-12 |
JP3376430B2 (ja) | 2003-02-10 |
ATE141283T1 (de) | 1996-08-15 |
CA2061167C (fr) | 2002-06-11 |
CA2061167A1 (fr) | 1992-08-16 |
DK0499541T3 (da) | 1996-12-02 |
FR2672895A1 (fr) | 1992-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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