ATE471376T1 - Verfahren zur herstellung von aktive, heterodimere, amv-reverse transkriptase in prokaryonten - Google Patents

Verfahren zur herstellung von aktive, heterodimere, amv-reverse transkriptase in prokaryonten

Info

Publication number
ATE471376T1
ATE471376T1 AT01121754T AT01121754T ATE471376T1 AT E471376 T1 ATE471376 T1 AT E471376T1 AT 01121754 T AT01121754 T AT 01121754T AT 01121754 T AT01121754 T AT 01121754T AT E471376 T1 ATE471376 T1 AT E471376T1
Authority
AT
Austria
Prior art keywords
amv
reverse transcriptase
prokaryonts
heterodimers
producing active
Prior art date
Application number
AT01121754T
Other languages
English (en)
Inventor
Harald Sobek
Rainer Mueller
Manfred Schmidt
Bruno Frey
Bernhard Suppmann
Rainer Schmuck
Johann-Peter Thalhofer
Peter Pallua
Markus Pajatsch
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE471376T1 publication Critical patent/ATE471376T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT01121754T 2000-09-22 2001-09-19 Verfahren zur herstellung von aktive, heterodimere, amv-reverse transkriptase in prokaryonten ATE471376T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10046960A DE10046960A1 (de) 2000-09-22 2000-09-22 Verfahren zur Herstellung einer aktiven, heterodimeren AMW-RT in prokaryotischen Zellen

Publications (1)

Publication Number Publication Date
ATE471376T1 true ATE471376T1 (de) 2010-07-15

Family

ID=7657206

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01121754T ATE471376T1 (de) 2000-09-22 2001-09-19 Verfahren zur herstellung von aktive, heterodimere, amv-reverse transkriptase in prokaryonten

Country Status (8)

Country Link
US (1) US6902920B2 (de)
EP (1) EP1191102B1 (de)
JP (1) JP2002315584A (de)
CN (1) CN1250728C (de)
AT (1) ATE471376T1 (de)
CA (1) CA2357540C (de)
DE (2) DE10046960A1 (de)
ES (1) ES2346511T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030219729A1 (en) * 2002-03-15 2003-11-27 Tosoh Corporation Unary avian myeloblastosis virus revers transcriptase and its use
AU2007292253A1 (en) * 2006-09-08 2008-03-13 Wyeth Arginine wash in protein purification using affinity chromatography
NZ600820A (en) * 2009-12-29 2014-12-24 Emergent Product Dev Seattle Heterodimer binding proteins and uses thereof
JP2012120506A (ja) * 2010-12-10 2012-06-28 Tosoh Corp Ａｍｖ逆転写酵素遺伝子、該遺伝子によりコードされるａｍｖ逆転写酵素及び該遺伝子を用いるａｍｖ逆転写酵素の製造方法
JP2013126402A (ja) * 2011-12-19 2013-06-27 Tosoh Corp 逆転写酵素の製造方法
JP2013146235A (ja) * 2012-01-20 2013-08-01 Tosoh Corp トリ骨髄芽細胞腫ウイルス逆転写酵素の製造方法
JP6107101B2 (ja) * 2012-12-11 2017-04-05 東ソー株式会社 トリ骨髄芽細胞腫ウイルス逆転写酵素の製造方法
CN108368151B (zh) * 2015-12-07 2022-11-15 生物辐射实验室股份有限公司 二聚逆转录酶
JP7753659B2 (ja) * 2021-04-19 2025-10-15 東ソー株式会社 トリ骨髄芽細胞腫ウイルス逆転写酵素発現ベクターおよび当該ベクターを用いた前記酵素の製造方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663290A (en) * 1982-01-21 1987-05-05 Molecular Genetics, Inc. Production of reverse transcriptase
US5244797B1 (en) * 1988-01-13 1998-08-25 Life Technologies Inc Cloned genes encoding reverse transcriptase lacking rnase h activity
KR100262258B1 (ko) * 1994-04-01 2000-07-15 다니엘 엘. 캐시앙, 헨리 엘. 노르호프, 피터 알. 쉬어리 고도로 정제된 재조합 역전사효소
JP3656277B2 (ja) * 1995-05-17 2005-06-08 味の素株式会社 組換えｄｎａ法によるトランスグルタミナーゼの効率的製造法
JPH09173078A (ja) * 1995-09-14 1997-07-08 Tadayuki Imanaka 分子シャペロンを用いる蛋白質の製造方法
US5641633A (en) 1995-11-15 1997-06-24 Becton, Dickinson And Company Fluorescence polarization detection of nucleic acids
AU721695B2 (en) * 1996-08-16 2000-07-13 Dong Wha Pharmaceutical Industrial Co., Ltd. HBV polymerase, RNase H enzyme derived from HBV polymerase, processes for preparation and uses for screening antiviral agents thereof
EP2184289A1 (de) * 1997-04-22 2010-05-12 Life Technologies Corporation Verfahren zur Herstellung von aus mehreren Untereinheiten zusammengesetzten ASLV-Umkehrtranskriptasen
JP3344618B2 (ja) * 1997-06-20 2002-11-11 株式会社エイチ・エス・ピー研究所 シャペロン発現プラスミド
CA2359538A1 (en) * 1999-01-15 2000-07-20 Neela Swaminathan Biologically active reverse transcriptases

Also Published As

Publication number Publication date
CA2357540A1 (en) 2002-03-22
DE10046960A1 (de) 2002-04-11
EP1191102A2 (de) 2002-03-27
US20020115147A1 (en) 2002-08-22
ES2346511T3 (es) 2010-10-18
EP1191102B1 (de) 2010-06-16
CN1250728C (zh) 2006-04-12
CA2357540C (en) 2010-07-13
JP2002315584A (ja) 2002-10-29
DE60142384D1 (de) 2010-07-29
EP1191102A3 (de) 2002-07-03
US6902920B2 (en) 2005-06-07
CN1346889A (zh) 2002-05-01

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