ATE466928T1 - Herstellung der lipid-modifizierten form des peptidoglykan-assoziierten lipoproteins aus gram- negativen bakterien - Google Patents

Herstellung der lipid-modifizierten form des peptidoglykan-assoziierten lipoproteins aus gram- negativen bakterien

Info

Publication number
ATE466928T1
ATE466928T1 AT00942996T AT00942996T ATE466928T1 AT E466928 T1 ATE466928 T1 AT E466928T1 AT 00942996 T AT00942996 T AT 00942996T AT 00942996 T AT00942996 T AT 00942996T AT E466928 T1 ATE466928 T1 AT E466928T1
Authority
AT
Austria
Prior art keywords
gram
peptidoglycan
negative bacteria
lipid
preparation
Prior art date
Application number
AT00942996T
Other languages
German (de)
English (en)
Inventor
Benjamin Metcalf
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE466928T1 publication Critical patent/ATE466928T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT00942996T 1999-06-25 2000-06-20 Herstellung der lipid-modifizierten form des peptidoglykan-assoziierten lipoproteins aus gram- negativen bakterien ATE466928T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14106199P 1999-06-25 1999-06-25
PCT/US2000/017020 WO2001000790A1 (en) 1999-06-25 2000-06-20 Production of the lipidated form of the peptidoglycan-associated lipoproteins of gram-negative bacteria

Publications (1)

Publication Number Publication Date
ATE466928T1 true ATE466928T1 (de) 2010-05-15

Family

ID=22493991

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00942996T ATE466928T1 (de) 1999-06-25 2000-06-20 Herstellung der lipid-modifizierten form des peptidoglykan-assoziierten lipoproteins aus gram- negativen bakterien

Country Status (15)

Country Link
US (2) US7452715B1 (ko)
EP (1) EP1192242B1 (ko)
JP (1) JP4660043B2 (ko)
KR (1) KR100833364B1 (ko)
CN (1) CN1192101C (ko)
AT (1) ATE466928T1 (ko)
AU (1) AU782566B2 (ko)
BR (1) BR0011804B1 (ko)
CA (1) CA2370887A1 (ko)
DE (1) DE60044352D1 (ko)
DK (1) DK1192242T3 (ko)
ES (1) ES2343304T3 (ko)
IL (1) IL146895A0 (ko)
MX (1) MXPA01013253A (ko)
WO (1) WO2001000790A1 (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2425855A1 (en) 2005-04-08 2012-03-07 Wyeth LLC Multivalent pneumococcal polysaccharide-protein conjugate composition
US7709001B2 (en) 2005-04-08 2010-05-04 Wyeth Llc Multivalent pneumococcal polysaccharide-protein conjugate composition
PT2351578T (pt) 2005-06-27 2017-04-07 Glaxosmithkline Biologicals Sa Processo para o fabrico de vacinas
EP1746103A1 (en) * 2005-07-20 2007-01-24 Applied NanoSystems B.V. Bifunctional protein anchors
WO2008105142A1 (ja) * 2007-02-28 2008-09-04 Nec Corporation マトリックス溶液
US8466259B2 (en) 2007-12-07 2013-06-18 National Health Research Institutes Adjuvants
US8426163B2 (en) * 2007-12-07 2013-04-23 National Health Research Institutes Production of lipidated proteins in E. coli
US8658176B2 (en) 2009-06-22 2014-02-25 National Health Research Institutes Lipidated tumor-associated antigens and immunotherapeutic compositions
TW201221642A (en) 2010-11-15 2012-06-01 Nat Health Research Institutes Method of producing lipidated polypeptides
TWI507413B (zh) 2010-11-15 2015-11-11 Nat Health Research Institutes 脂質化多抗原表位疫苗
CN103468704B (zh) * 2012-11-06 2015-01-07 中山大学 肽聚糖结合蛋白BjApextrin2及其基因、生产方法和应用
CN102925447B (zh) * 2012-11-06 2014-04-02 中山大学 肽聚糖结合蛋白BjApextrin1及其基因、生产方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340888C (en) * 1988-09-01 2000-02-01 Algis Anilionis Vaccines and diagnostic assays for haemophilus influenzae
JPH11507532A (ja) * 1995-06-07 1999-07-06 ワシントン ユニバーシティ 環境に制限される生存能を有する組換え細菌システム
ES2337027T3 (es) * 1997-12-05 2010-04-20 Europaisches Laboratorium Fur Molekularbiologie (Embl) Nuevo metodo de clonacion de dna basado en el sistema de recombinacion rece-rect de e. coli.

Also Published As

Publication number Publication date
KR100833364B1 (ko) 2008-05-28
BR0011804A (pt) 2002-03-19
WO2001000790A1 (en) 2001-01-04
KR20020039270A (ko) 2002-05-25
EP1192242A1 (en) 2002-04-03
DK1192242T3 (da) 2010-07-26
US7741076B2 (en) 2010-06-22
CN1358227A (zh) 2002-07-10
IL146895A0 (en) 2002-08-14
AU782566B2 (en) 2005-08-11
BR0011804B1 (pt) 2011-11-01
CA2370887A1 (en) 2001-01-04
CN1192101C (zh) 2005-03-09
WO2001000790A9 (en) 2009-12-23
JP2003503043A (ja) 2003-01-28
AU5753400A (en) 2001-01-31
US7452715B1 (en) 2008-11-18
JP4660043B2 (ja) 2011-03-30
MXPA01013253A (es) 2002-06-04
ES2343304T3 (es) 2010-07-28
EP1192242B1 (en) 2010-05-05
DE60044352D1 (de) 2010-06-17
US20090060952A1 (en) 2009-03-05

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