ATE46157T1 - Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel. - Google Patents

Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel.

Info

Publication number
ATE46157T1
ATE46157T1 AT87401244T AT87401244T ATE46157T1 AT E46157 T1 ATE46157 T1 AT E46157T1 AT 87401244 T AT87401244 T AT 87401244T AT 87401244 T AT87401244 T AT 87401244T AT E46157 T1 ATE46157 T1 AT E46157T1
Authority
AT
Austria
Prior art keywords
benzo
thiophen
manufacture
methods
pharmaceuticals containing
Prior art date
Application number
AT87401244T
Other languages
English (en)
Inventor
Marie-Christine Dubroeucq
Christian Renault
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Application granted granted Critical
Publication of ATE46157T1 publication Critical patent/ATE46157T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT87401244T 1986-06-05 1987-06-04 Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel. ATE46157T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8608110A FR2599740B1 (fr) 1986-06-05 1986-06-05 Derives de benzo(b)thiophene de benzo(b)furannecarboxamides, leurs procedes de preparation et les medicaments les contenant
EP87401244A EP0248734B1 (de) 1986-06-05 1987-06-04 Benzo[b]thiophen und Benzo[b]furancarboxamid-Derivate, ihre Verfahren zur Herstellung und sie enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ATE46157T1 true ATE46157T1 (de) 1989-09-15

Family

ID=9336032

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87401244T ATE46157T1 (de) 1986-06-05 1987-06-04 Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel.

Country Status (14)

Country Link
US (1) US4808599A (de)
EP (1) EP0248734B1 (de)
JP (1) JPS6339874A (de)
AT (1) ATE46157T1 (de)
AU (1) AU591780B2 (de)
CA (1) CA1280115C (de)
DE (1) DE3760532D1 (de)
DK (1) DK289087A (de)
ES (1) ES2011296B3 (de)
FR (1) FR2599740B1 (de)
GR (1) GR3000148T3 (de)
NZ (1) NZ220546A (de)
PT (1) PT85014B (de)
ZA (1) ZA873978B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196849B (it) * 1986-12-16 1988-11-25 Rotta Research Lab Nuovi derivati degli acidi 5 pentilammino 5 oxo pentaoico e 4 pentilammino 4 oxo butanoico ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
JP3415946B2 (ja) * 1994-10-31 2003-06-09 タイコエレクトロニクスアンプ株式会社 電気コネクタ
US5776946A (en) * 1995-08-28 1998-07-07 Mcgeer; Patrick L. Peripheral benzodiazepine receptor ligands as antiinflammatory agents
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
AU4072799A (en) 1998-05-12 1999-12-13 American Home Products Corporation 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
EA200001175A1 (ru) * 1998-05-12 2001-06-25 Американ Хоум Продактс Корпорейшн Бензотиофены, бензофураны и индолы, полезные в лечении устойчивости к инсулину и гипергликемии
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6110962A (en) * 1998-05-12 2000-08-29 American Home Products Corporation 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
EP1140106B1 (de) 1998-12-18 2005-08-03 Scios Inc. Behandlung von erkrankungen mit zystenbildung
AU2185100A (en) 1998-12-18 2000-07-12 Scios Inc. Agonists and antagonists of peripheral-type benzodiazepine receptors
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
JP3745608B2 (ja) 2000-09-27 2006-02-15 矢崎総業株式会社 フロントホルダの係止構造
JP4678139B2 (ja) * 2004-05-10 2011-04-27 トヨタ自動車株式会社 自動車の暖房制御システム
WO2006010379A1 (en) * 2004-07-29 2006-02-02 Actelion Pharmaceuticals Ltd. Novel thiophene derivatives as immunosuppressive agents
BRPI0609665A2 (pt) 2005-03-23 2010-04-20 Actelion Pharmaceuticals Ltd composto, composição farmacêutica, e, uso de um composto
PT1863787E (pt) * 2005-03-23 2011-07-29 Actelion Pharmaceuticals Ltd Derivados de benzo(c)tiofenos hidrogenados como imunomoduladores
AU2007209051A1 (en) 2006-01-24 2007-08-02 Actelion Pharmaceuticals Ltd Novel pyridine derivatives
GB0905328D0 (en) 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives
ES2688574T3 (es) * 2010-03-26 2018-11-05 Ge Healthcare Limited Derivados de indol tricíclicos como ligandos de PBR
US9220795B2 (en) 2011-09-22 2015-12-29 Ge Healthcare Limited Indole derivatives
GB201312768D0 (en) 2013-07-17 2013-08-28 Ge Healthcare Ltd Work-up procedure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents

Also Published As

Publication number Publication date
FR2599740A1 (fr) 1987-12-11
JPS6339874A (ja) 1988-02-20
AU591780B2 (en) 1989-12-14
US4808599A (en) 1989-02-28
ZA873978B (en) 1987-12-02
FR2599740B1 (fr) 1988-08-12
DK289087D0 (da) 1987-06-04
EP0248734B1 (de) 1989-09-06
PT85014B (pt) 1990-03-08
AU7378587A (en) 1987-12-10
EP0248734A1 (de) 1987-12-09
PT85014A (fr) 1987-07-01
NZ220546A (en) 1989-02-24
DK289087A (da) 1987-12-06
DE3760532D1 (en) 1989-10-12
ES2011296B3 (es) 1990-01-01
CA1280115C (fr) 1991-02-12
GR3000148T3 (en) 1990-11-29

Similar Documents

Publication Publication Date Title
ATE46157T1 (de) Benzo(b>thiophen und benzo(b>furancarboxamidderivate, ihre verfahren zur herstellung und sie enthaltende arzneimittel.
ATE168373T1 (de) Benzofuranyl- und thiophenylalkancarbonsäurederivate
DE3866086D1 (de) Verfahren zur synthese von 3-thia-4-chinolonderivaten und zwischenprodukte dafuer und ihre verwendung als arzneimittel.
ATE211474T1 (de) Galanthamin derivate, verfahren zu ihrer herstellung und ihre verwendung als medikamente
ATE144498T1 (de) Herstellung von substituierten piperidinen
AT380471B (de) Verfahren zur herstellung von neuen 2-oxoazetidin-derivate
ATE62686T1 (de) Neue 3-oxadiazol- und 3-carbonsaeure-betacarbolinderivate, ihre herstellung und ihre verwendung als arzneimittel.
ATE132861T1 (de) Derivate von hexahydroazepine, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
ATE40370T1 (de) Phenylengruppen-haltige organosilane, verfahren zu ihrer herstellung.
DK282285A (da) Hidtil ukendte 8-alkylthio-2-piperazino-pyrimido(5,4-d)pyrimidiner,deres fremstilling og laegemidler indeholdende disse forbindelser
ES2109530T3 (es) Derivados de acidos fenil-ciclohexano-carboxilicos heterotriciclicamente sustituidos.
ATE37534T1 (de) Arylethanolhydroxylamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung.
DE58902320D1 (de) Thienyl-piperazinone, ihre herstellung und verwendung.
FI914715A (fi) Anvaendning av fosfonsyradiglycidylestrar som foernaetningsmedel vid framstaellning av hydrogel.
DE3677857D1 (de) 2,5-dimethylpyrrolderivative, ihre herstellung und ihre verwendung.
ATE89282T1 (de) 1-dethia-2-thia-cephalosporansaeurederivate, verfahren zur herstellung, ihre verwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen.
ATE7298T1 (de) Basisch substituierte 5-phenyltetrazole, verfahren zu ihrer herstellung und ihre verwendung als heilmittel.
NO305556B1 (no) Tiokarbamoylforbindelser og anvendelse derav samt middel for beskyttelse av tekniske materialer
ATE16807T1 (de) Neue 4-hydroxy-2h-1,2-benzothiazin-3-carboxamid1,1-dioxide, verfahren zu ihrer herstellung, ihre verwendung und diese verbindungen enthaltende arzneimittel.
ATE67194T1 (de) Thiadiazolylacetamid-derivate, verfahren zu ihrer herstellung und ihre verwendung.
DE69109953T2 (de) Alfa-fluorocarbonsäurederivate als Zwischenprodukte zur Herstellung von Fungiziden.
ATE17490T1 (de) Dithiino (1,4) (2,3-c) pyrrolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee