ES2011296B3 - Derivados de benzo[b]tiofeno y benzo [b]furano carboxamidas, sus procedimientos de preparacion y los medicamentos que los contienen. - Google Patents

Derivados de benzo[b]tiofeno y benzo [b]furano carboxamidas, sus procedimientos de preparacion y los medicamentos que los contienen.

Info

Publication number
ES2011296B3
ES2011296B3 ES87401244T ES87401244T ES2011296B3 ES 2011296 B3 ES2011296 B3 ES 2011296B3 ES 87401244 T ES87401244 T ES 87401244T ES 87401244 T ES87401244 T ES 87401244T ES 2011296 B3 ES2011296 B3 ES 2011296B3
Authority
ES
Spain
Prior art keywords
benzo
thiofen
furano
carboxamides
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87401244T
Other languages
English (en)
Inventor
Marie-Christine Dubroeucq
Christian Renault
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of ES2011296B3 publication Critical patent/ES2011296B3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES87401244T 1986-06-05 1987-06-04 Derivados de benzo[b]tiofeno y benzo [b]furano carboxamidas, sus procedimientos de preparacion y los medicamentos que los contienen. Expired - Lifetime ES2011296B3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8608110A FR2599740B1 (fr) 1986-06-05 1986-06-05 Derives de benzo(b)thiophene de benzo(b)furannecarboxamides, leurs procedes de preparation et les medicaments les contenant

Publications (1)

Publication Number Publication Date
ES2011296B3 true ES2011296B3 (es) 1990-01-01

Family

ID=9336032

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87401244T Expired - Lifetime ES2011296B3 (es) 1986-06-05 1987-06-04 Derivados de benzo[b]tiofeno y benzo [b]furano carboxamidas, sus procedimientos de preparacion y los medicamentos que los contienen.

Country Status (14)

Country Link
US (1) US4808599A (es)
EP (1) EP0248734B1 (es)
JP (1) JPS6339874A (es)
AT (1) ATE46157T1 (es)
AU (1) AU591780B2 (es)
CA (1) CA1280115C (es)
DE (1) DE3760532D1 (es)
DK (1) DK289087A (es)
ES (1) ES2011296B3 (es)
FR (1) FR2599740B1 (es)
GR (1) GR3000148T3 (es)
NZ (1) NZ220546A (es)
PT (1) PT85014B (es)
ZA (1) ZA873978B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196849B (it) * 1986-12-16 1988-11-25 Rotta Research Lab Nuovi derivati degli acidi 5 pentilammino 5 oxo pentaoico e 4 pentilammino 4 oxo butanoico ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
JP3415946B2 (ja) * 1994-10-31 2003-06-09 タイコエレクトロニクスアンプ株式会社 電気コネクタ
US5776946A (en) * 1995-08-28 1998-07-07 Mcgeer; Patrick L. Peripheral benzodiazepine receptor ligands as antiinflammatory agents
WO1999061410A1 (en) 1998-05-12 1999-12-02 American Home Products Corporation 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
US6232322B1 (en) 1998-05-12 2001-05-15 American Home Products Corporation Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6699896B1 (en) 1998-05-12 2004-03-02 Wyeth Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6110962A (en) * 1998-05-12 2000-08-29 American Home Products Corporation 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia
CA2330620A1 (en) * 1998-05-12 1999-12-02 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
US6221902B1 (en) 1998-05-12 2001-04-24 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
US6110963A (en) * 1998-05-12 2000-08-29 American Home Products Corporation Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
US6451827B2 (en) 1998-05-12 2002-09-17 Wyeth 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia
FR2778564B1 (fr) * 1998-05-13 2001-07-13 Sanofi Sa Utilisation de composes reduisant l'apoptose
WO1999058117A1 (fr) * 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
ATE333281T1 (de) 1998-12-18 2006-08-15 Scios Inc Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs
DE69926535T2 (de) 1998-12-18 2006-03-30 Scios Inc., Sunnyvale Behandlung von erkrankungen mit zystenbildung
US6310081B1 (en) 1999-05-10 2001-10-30 American Home Products Corporation Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia
JP3745608B2 (ja) 2000-09-27 2006-02-15 矢崎総業株式会社 フロントホルダの係止構造
JP4678139B2 (ja) * 2004-05-10 2011-04-27 トヨタ自動車株式会社 自動車の暖房制御システム
WO2006010379A1 (en) * 2004-07-29 2006-02-02 Actelion Pharmaceuticals Ltd. Novel thiophene derivatives as immunosuppressive agents
BRPI0609515A8 (pt) * 2005-03-23 2017-12-26 Actelion Pharmaceuticals Ltd Composto, composição farmacêutica, e, uso de um composto
WO2006100635A2 (en) 2005-03-23 2006-09-28 Actelion Pharmaceuticals Ltd Novel thiophene derivatives as sphingosine-1-phosphate-1 receptor agonists
ES2335242T3 (es) 2006-01-24 2010-03-23 Actelion Pharmaceuticals Ltd. Derivados novedosos de piridina.
GB0905328D0 (en) 2009-03-27 2009-05-13 Ge Healthcare Ltd Indole derivatives
SG183837A1 (en) * 2010-03-26 2012-10-30 Ge Healthcare Ltd Tricyclic indole derivatives as pbr ligands
US9220795B2 (en) 2011-09-22 2015-12-29 Ge Healthcare Limited Indole derivatives
GB201312768D0 (en) * 2013-07-17 2013-08-28 Ge Healthcare Ltd Work-up procedure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents

Also Published As

Publication number Publication date
US4808599A (en) 1989-02-28
NZ220546A (en) 1989-02-24
DK289087D0 (da) 1987-06-04
EP0248734A1 (fr) 1987-12-09
GR3000148T3 (en) 1990-11-29
EP0248734B1 (fr) 1989-09-06
PT85014A (fr) 1987-07-01
DE3760532D1 (en) 1989-10-12
DK289087A (da) 1987-12-06
PT85014B (pt) 1990-03-08
CA1280115C (fr) 1991-02-12
AU7378587A (en) 1987-12-10
ATE46157T1 (de) 1989-09-15
FR2599740A1 (fr) 1987-12-11
JPS6339874A (ja) 1988-02-20
ZA873978B (en) 1987-12-02
FR2599740B1 (fr) 1988-08-12
AU591780B2 (en) 1989-12-14

Similar Documents

Publication Publication Date Title
ES2011296B3 (es) Derivados de benzo[b]tiofeno y benzo [b]furano carboxamidas, sus procedimientos de preparacion y los medicamentos que los contienen.
SE8406585D0 (sv) Benzoic acid derivatives
ES506115A0 (es) Procedimiento para la obtencion de compuestos de b-lactama.
ES2074846T3 (es) Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.
DK506587D0 (da) Imidderivater
ATE170521T1 (de) 1-methyl-carbapenemderivate, deren herstellung und verwendung als antibiotika
PT83725B (pt) Processo para preparacao de novos derivados da 3-oxadiol-beta-carbolina e 3-carboxilato-beta-carbolina e de composicoes farmaceuticas que os contem
MX9203360A (es) Derivados de hexahidroazepinas y composiciones farmaceuticas que los contienen.
NO854677L (no) Fremgangsmaate for fremstilling av 5-alkyl-1-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
PT91555A (pt) Processo de preparacao de derivados de dibenzo{2,3:6,7}-(oxepino ou tiepino){4,5-c}(piridina ou pirrol)e de composicoes farmaceuticas que os contem
ES2078911T3 (es) Fenil-heterociclos disustituidos en 3,4 y su utilizacion.
ATE89282T1 (de) 1-dethia-2-thia-cephalosporansaeurederivate, verfahren zur herstellung, ihre verwendung als arzneimittel und sie enthaltende pharmazeutische zusammensetzungen.
ATE42287T1 (de) Homocysteinthiolactonderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES2063157T3 (es) Nuevos derivados del indol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
PT90815A (pt) Processo de preparacao de derivados da fenotiazina
PT93904A (pt) Processo para a preparacao de novos derivados benzotiazolinonicos e de composicoes farmaceuticas que os contem
ATE96774T1 (de) Hydroxyphenethylamin-derivat und dessen salze, verfahren zur herstellung, medizinische verwendung und verwendung als spezifisches pharmakologisches werkzeug.
NO305556B1 (no) Tiokarbamoylforbindelser og anvendelse derav samt middel for beskyttelse av tekniske materialer
ATE126516T1 (de) Tetrahydro-2,3,6,7,1h,5h,11h-
FI911616A (fi) Substituerade 3-tia- eller 3-oxa-alkyl -flavoner, foerfarande foer deras framstaellning, deras anvaendning, pao dessa foereningar baserade laekemedel samt mellanprodukter.
ATE17490T1 (de) Dithiino (1,4) (2,3-c) pyrrolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.
ATE20749T1 (de) Dithiino (1,4) (2,3-c) pyrrolderivate, ihre herstellung und solche enthaltende arzneimittel.