ATE460937T1 - Mikronisierte tanaproget zusammensetzungen und verfahren zu ihrer herstellung - Google Patents
Mikronisierte tanaproget zusammensetzungen und verfahren zu ihrer herstellungInfo
- Publication number
- ATE460937T1 ATE460937T1 AT06751506T AT06751506T ATE460937T1 AT E460937 T1 ATE460937 T1 AT E460937T1 AT 06751506 T AT06751506 T AT 06751506T AT 06751506 T AT06751506 T AT 06751506T AT E460937 T1 ATE460937 T1 AT E460937T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- methods
- micronized tanaproget
- tanaproget compositions
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/536—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US67555005P | 2005-04-28 | 2005-04-28 | |
PCT/US2006/015837 WO2006116514A2 (en) | 2005-04-28 | 2006-04-26 | Micronized tanaproget, compositions, and methods of preparing the same |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE460937T1 true ATE460937T1 (de) | 2010-04-15 |
Family
ID=37023145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06751506T ATE460937T1 (de) | 2005-04-28 | 2006-04-26 | Mikronisierte tanaproget zusammensetzungen und verfahren zu ihrer herstellung |
Country Status (19)
Country | Link |
---|---|
US (4) | US7767668B2 (de) |
EP (1) | EP1896034B8 (de) |
JP (2) | JP5149159B2 (de) |
CN (1) | CN101166532B (de) |
AR (1) | AR056328A1 (de) |
AT (1) | ATE460937T1 (de) |
AU (1) | AU2006241113B2 (de) |
BR (1) | BRPI0610437A2 (de) |
CA (1) | CA2603806C (de) |
CY (1) | CY1110009T1 (de) |
DE (1) | DE602006012972D1 (de) |
DK (1) | DK1896034T3 (de) |
ES (1) | ES2340610T3 (de) |
MX (1) | MX2007013465A (de) |
PL (1) | PL1896034T3 (de) |
PT (1) | PT1896034E (de) |
SI (1) | SI1896034T1 (de) |
TW (1) | TW200716129A (de) |
WO (1) | WO2006116514A2 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006084058A2 (en) | 2005-02-03 | 2006-08-10 | The General Hospital Corporation | Method for treating gefitinib resistant cancer |
CA2603594C (en) | 2005-04-28 | 2013-11-05 | Wyeth | Micronized tanaproget and compositions containing same |
EP1874278B1 (de) * | 2005-04-28 | 2009-06-24 | Wyeth | Zusammensetzungen mit mikronisiertem tanaproget |
MX2007013469A (es) * | 2005-04-28 | 2008-01-22 | Wyeth Corp | Forma ii polimorfa de tanaproget. |
DK1896034T3 (da) | 2005-04-28 | 2010-05-17 | Wyeth Corp | Mikroniserede tanaproget-sammensætninger og fremgangsmåder til fremstilling af disse |
BRPI0611250A2 (pt) | 2005-06-09 | 2011-02-15 | Wyeth Corp | composto, enanciÈmeros, diastereoisÈmeros do mesmo ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de um composto |
TW200803892A (en) | 2005-11-04 | 2008-01-16 | Wyeth Corp | Antineoplastic combinations with MTOR inhibitor, herceptin, and/or HKI-272 |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
US9040825B2 (en) * | 2007-11-13 | 2015-05-26 | Southwire Company, Llc | Conductors and metal-covered cable with coded information and method of applying coded information |
EA201070715A1 (ru) * | 2007-12-20 | 2011-02-28 | Тева Вимен'С Хелс, Инк. | Режимы дозирования, фармацевтические композиции и упаковки для экстренной контрацепции |
ES2531322T3 (es) | 2008-06-17 | 2015-03-13 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
NZ590464A (en) | 2008-08-04 | 2012-10-26 | Wyeth Llc | Antineoplastic combinations of the 4-anilino-3-cyanoquinoline neratinib and capecitabine |
KR20160106211A (ko) | 2009-04-06 | 2016-09-09 | 와이어쓰 엘엘씨 | 네라티닙을 이용한 유방암의 치료법 |
CN103893140B (zh) * | 2009-11-09 | 2016-06-01 | 惠氏有限责任公司 | 来那替尼马来酸盐的片剂制剂 |
CN102724962B (zh) | 2009-11-09 | 2017-05-17 | 惠氏有限责任公司 | 包衣药物球状体及其用于消除或减少病症比如呕吐和腹泻的用途 |
WO2011074961A1 (en) | 2009-12-18 | 2011-06-23 | Frieslandcampina Nederland Holding B.V. | Co-processed tablet excipient composition its preparation and use |
US9326997B2 (en) | 2012-09-24 | 2016-05-03 | Ahlam E. Elakkad | Composition and method for treation Oligoovulation, Oligomenorrhea and Amenorrhea |
MX2015016038A (es) | 2013-05-21 | 2016-03-21 | Predictive Therapheutics Llc | Agente terapéutico y método de uso. |
GB201318394D0 (en) * | 2013-10-17 | 2013-12-04 | Univ Edinburgh | Composition |
WO2023025672A1 (en) | 2021-08-25 | 2023-03-02 | Basf Se | Direct tableting auxiliary composition |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SG120970A1 (en) * | 1999-05-04 | 2006-04-26 | Ligand Pharm Inc | Cyclothiocarbamate derivatives as progesterone receptor modulators |
UA73119C2 (en) * | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
US6962908B2 (en) * | 2001-12-21 | 2005-11-08 | Warner Chilcott Company Inc. | Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation |
EP1531824A4 (de) * | 2002-06-25 | 2005-09-21 | Wyeth Corp | Cyclothiocarbamat-derivate als pr-modulatoren und ihre verwendung bei der behandlung von hauterkrankungen |
CN1662241A (zh) * | 2002-06-25 | 2005-08-31 | 惠氏公司 | 环硫代氨基甲酸酯衍生物在治疗与激素有关的病症中的用途 |
US8404272B2 (en) * | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
US7514466B2 (en) | 2004-04-27 | 2009-04-07 | Wyeth | Purification of progesterone receptor modulators |
TW200604137A (en) | 2004-04-27 | 2006-02-01 | Wyeth Corp | Coupling process for generating reactive boron-containing derivatives of n-substituted pyrrole-2-carbonitriles to produce biaryls |
ATE396189T1 (de) * | 2004-04-27 | 2008-06-15 | Wyeth Corp | Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellung |
AU2005269938A1 (en) * | 2004-07-07 | 2006-02-09 | Wyeth | Cyclic progestin regimens and kits |
GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
GT200500183A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
WO2006020712A1 (en) * | 2004-08-13 | 2006-02-23 | Wyeth | Tanaproget derivatives, metabolites, and uses thereof |
US7496489B2 (en) * | 2004-08-20 | 2009-02-24 | Wyeth | Design of progesterone receptor ligands |
CA2603594C (en) | 2005-04-28 | 2013-11-05 | Wyeth | Micronized tanaproget and compositions containing same |
EP1874278B1 (de) * | 2005-04-28 | 2009-06-24 | Wyeth | Zusammensetzungen mit mikronisiertem tanaproget |
MX2007013469A (es) | 2005-04-28 | 2008-01-22 | Wyeth Corp | Forma ii polimorfa de tanaproget. |
DK1896034T3 (da) * | 2005-04-28 | 2010-05-17 | Wyeth Corp | Mikroniserede tanaproget-sammensætninger og fremgangsmåder til fremstilling af disse |
EP1874743B1 (de) * | 2005-04-28 | 2013-07-17 | Wyeth LLC | Gereinigte form von tanaproget |
BRPI0611250A2 (pt) * | 2005-06-09 | 2011-02-15 | Wyeth Corp | composto, enanciÈmeros, diastereoisÈmeros do mesmo ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de um composto |
-
2006
- 2006-04-26 DK DK06751506.4T patent/DK1896034T3/da active
- 2006-04-26 SI SI200630649T patent/SI1896034T1/sl unknown
- 2006-04-26 PL PL06751506T patent/PL1896034T3/pl unknown
- 2006-04-26 CN CN2006800142294A patent/CN101166532B/zh not_active Expired - Fee Related
- 2006-04-26 MX MX2007013465A patent/MX2007013465A/es active IP Right Grant
- 2006-04-26 EP EP06751506A patent/EP1896034B8/de not_active Not-in-force
- 2006-04-26 ES ES06751506T patent/ES2340610T3/es active Active
- 2006-04-26 WO PCT/US2006/015837 patent/WO2006116514A2/en active Application Filing
- 2006-04-26 TW TW095114814A patent/TW200716129A/zh unknown
- 2006-04-26 US US11/411,523 patent/US7767668B2/en not_active Expired - Fee Related
- 2006-04-26 JP JP2008509087A patent/JP5149159B2/ja not_active Expired - Fee Related
- 2006-04-26 CA CA2603806A patent/CA2603806C/en not_active Expired - Fee Related
- 2006-04-26 DE DE602006012972T patent/DE602006012972D1/de active Active
- 2006-04-26 AR ARP060101669A patent/AR056328A1/es not_active Application Discontinuation
- 2006-04-26 BR BRPI0610437-1A patent/BRPI0610437A2/pt not_active IP Right Cessation
- 2006-04-26 AT AT06751506T patent/ATE460937T1/de active
- 2006-04-26 PT PT06751506T patent/PT1896034E/pt unknown
- 2006-04-26 AU AU2006241113A patent/AU2006241113B2/en not_active Ceased
-
2010
- 2010-04-01 US US12/752,520 patent/US8450312B2/en not_active Expired - Fee Related
- 2010-04-20 CY CY20101100356T patent/CY1110009T1/el unknown
-
2012
- 2012-07-31 JP JP2012169771A patent/JP2013006840A/ja active Pending
-
2013
- 2013-05-09 US US13/890,523 patent/US8772271B2/en not_active Expired - Fee Related
-
2014
- 2014-06-02 US US14/293,070 patent/US20140328925A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20130251807A1 (en) | 2013-09-26 |
DE602006012972D1 (de) | 2010-04-29 |
DK1896034T3 (da) | 2010-05-17 |
WO2006116514A2 (en) | 2006-11-02 |
AU2006241113B2 (en) | 2011-08-18 |
JP2013006840A (ja) | 2013-01-10 |
ES2340610T3 (es) | 2010-06-07 |
JP5149159B2 (ja) | 2013-02-20 |
PL1896034T3 (pl) | 2010-07-30 |
US7767668B2 (en) | 2010-08-03 |
CA2603806A1 (en) | 2006-11-02 |
US20100189789A1 (en) | 2010-07-29 |
CY1110009T1 (el) | 2015-01-14 |
US8450312B2 (en) | 2013-05-28 |
MX2007013465A (es) | 2008-01-21 |
EP1896034B1 (de) | 2010-03-17 |
US8772271B2 (en) | 2014-07-08 |
JP2008539256A (ja) | 2008-11-13 |
CN101166532B (zh) | 2011-06-22 |
EP1896034A2 (de) | 2008-03-12 |
US20140328925A1 (en) | 2014-11-06 |
SI1896034T1 (sl) | 2010-07-30 |
BRPI0610437A2 (pt) | 2012-10-23 |
AR056328A1 (es) | 2007-10-03 |
TW200716129A (en) | 2007-05-01 |
US20060246135A1 (en) | 2006-11-02 |
EP1896034B8 (de) | 2010-05-19 |
CN101166532A (zh) | 2008-04-23 |
AU2006241113A1 (en) | 2006-11-02 |
CA2603806C (en) | 2013-03-19 |
WO2006116514A3 (en) | 2006-12-14 |
PT1896034E (pt) | 2010-05-06 |
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