ATE396189T1 - Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellung - Google Patents
Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellungInfo
- Publication number
- ATE396189T1 ATE396189T1 AT05740218T AT05740218T ATE396189T1 AT E396189 T1 ATE396189 T1 AT E396189T1 AT 05740218 T AT05740218 T AT 05740218T AT 05740218 T AT05740218 T AT 05740218T AT E396189 T1 ATE396189 T1 AT E396189T1
- Authority
- AT
- Austria
- Prior art keywords
- optionally substituted
- methyl
- alkyl
- cyanopyrrole
- aminoalkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56561604P | 2004-04-27 | 2004-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE396189T1 true ATE396189T1 (de) | 2008-06-15 |
Family
ID=35242253
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05740218T ATE396189T1 (de) | 2004-04-27 | 2005-04-25 | Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellung |
Country Status (14)
Country | Link |
---|---|
US (3) | US7582755B2 (de) |
EP (1) | EP1756095B1 (de) |
JP (2) | JP5108506B2 (de) |
CN (1) | CN1946716B (de) |
AT (1) | ATE396189T1 (de) |
AU (1) | AU2005238520B2 (de) |
BR (1) | BRPI0510278A (de) |
CA (1) | CA2562160C (de) |
DE (1) | DE602005007021D1 (de) |
DK (1) | DK1756095T3 (de) |
ES (1) | ES2306140T3 (de) |
MX (1) | MXPA06012402A (de) |
PL (1) | PL1756095T3 (de) |
WO (1) | WO2005105739A2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
MXPA06012402A (es) | 2004-04-27 | 2007-01-17 | Wyeth Corp | Carbamato y tiocarbamato biarilos ciclicos que contienen cianopirrol y metodos para preparar los mismos. |
DE602006013114D1 (de) * | 2005-04-28 | 2010-05-06 | Wyeth Corp | Mikronisiertes tanaproget und zusammensetzungen damit |
AU2006287925B2 (en) * | 2005-04-28 | 2012-03-01 | Wyeth | Compositions containing micronized tanaproget |
TW200716129A (en) * | 2005-04-28 | 2007-05-01 | Wyeth Corp | Micronized tanaproget, compositions, and methods of preparing the same |
PE20070220A1 (es) * | 2005-07-29 | 2007-03-19 | Wyeth Corp | Proceso para la sintesis de moduladores del receptor de progesterona |
PE20070341A1 (es) * | 2005-07-29 | 2007-04-13 | Wyeth Corp | Derivados de pirrol como moduladores del receptor de progesterona |
PE20070182A1 (es) * | 2005-07-29 | 2007-03-06 | Wyeth Corp | Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona |
PE20070404A1 (es) * | 2005-07-29 | 2007-05-10 | Wyeth Corp | Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona |
US20070213526A1 (en) * | 2006-03-07 | 2007-09-13 | Wyeth | Purification of progesterone receptor modulators |
US20080319204A1 (en) * | 2007-06-25 | 2008-12-25 | Wyeth | Process for the synthesis of progesterone receptor modulators |
WO2009082478A1 (en) | 2007-12-20 | 2009-07-02 | Duramed Pharmaceuticals, Inc. | Dosage regimens and pharmaceutical compositions and packages for emergency contraception |
GB0817578D0 (en) * | 2008-09-25 | 2008-11-05 | 3M Innovative Properties Co | Method for treating wheel rims and composition for use therein |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5194628A (en) | 1988-03-18 | 1993-03-16 | Ciba-Geigy Corporation | Process for the preparation of substituted difluorobenzo-1,3-dioxoles |
JPH09502432A (ja) | 1993-09-10 | 1997-03-11 | チバ−ガイギー アクチエンゲゼルシャフト | フォトクロミック化合物、その製造方法および製造のための中間生成物、ならびにそれらの用法 |
US6545108B1 (en) | 1999-02-22 | 2003-04-08 | Eastman Chemical Company | Catalysts containing N-pyrrolyl substituted nitrogen donors |
EP1192189B1 (de) | 1999-02-22 | 2004-09-29 | Eastman Chemical Company | Katalysatoren, die n-pyrrolylsubstituierte stickstoffdonoren enthalten |
US6391907B1 (en) | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
BR0010213A (pt) * | 1999-05-04 | 2002-02-19 | American Home Prod | Derivados de ciclocarbamato como moduladores de receptor de progesterona |
CN1131856C (zh) * | 1999-05-04 | 2003-12-24 | 美国家庭用品有限公司 | 作为黄体酮受体调节剂的环硫代氨基甲酸酯衍生物 |
WO2000066560A1 (en) * | 1999-05-04 | 2000-11-09 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
US6509334B1 (en) | 1999-05-04 | 2003-01-21 | American Home Products Corporation | Cyclocarbamate derivatives as progesterone receptor modulators |
AU4814000A (en) * | 1999-05-04 | 2000-11-17 | American Home Products Corporation | Quinazolinone and benzoxazine derivatives as progesterone receptor modulators |
US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
US20020065192A1 (en) | 2000-02-18 | 2002-05-30 | Mackenzie Peter Borden | Productivity catalysts and microstructure control |
UA73119C2 (en) | 2000-04-19 | 2005-06-15 | American Home Products Corpoir | Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors |
US6350837B1 (en) | 2000-06-09 | 2002-02-26 | Eastman Chemical Company | Copolymerization of norbornene and functional norbornene monomers |
WO2002036641A2 (en) | 2000-11-06 | 2002-05-10 | Eastman Chemical Company | Improved productivity catalysts and microstructure control |
WO2002036642A2 (en) | 2000-11-06 | 2002-05-10 | Eastman Chemical Company | Olefin polymerization processes using supported catalysts |
US6387992B1 (en) | 2000-11-27 | 2002-05-14 | Ciba Specialty Chemicals Corporation | Substituted 5-heteroaryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, a process for preparation thereof and compositions stabilized therewith |
JP4307071B2 (ja) | 2000-11-27 | 2009-08-05 | チバ ホールディング インコーポレーテッド | Uv吸収剤としての置換5−アリール及び5−ヘテロアリール−2−(2−ヒドロキシフェニル)−2h−ベンゾトリアゾール誘導体 |
DE10111262A1 (de) | 2001-03-09 | 2002-09-12 | Studiengesellschaft Kohle Mbh | Verfahren zur Herstellung von Vinyl- Aryl- und Heteroarylessigsäuren und ihrer Devivate |
JP2005194190A (ja) | 2001-10-05 | 2005-07-21 | Fumie Satou | 19−ノル−ビタミンd誘導体の製造法 |
DE10152989A1 (de) | 2001-10-26 | 2003-05-08 | Bayer Ag | Komplexe N-heterocyslischer Carbene und ihre Verwendung |
WO2003105860A1 (en) | 2002-06-14 | 2003-12-24 | Novo Nordisk A/S | Pharmaceutical use of boronic acids and esters thereof |
AU2003247608A1 (en) * | 2002-06-25 | 2004-01-06 | Wyeth | Use of cyclothiocarbamate derivatives in treatment of hormone-related conditions |
AU2003245657A1 (en) * | 2002-06-25 | 2004-01-06 | Wyeth | Cyclothiocarbamative derivatives as pr modulators and use thereof for treatment of skin disorders |
MXPA06012402A (es) | 2004-04-27 | 2007-01-17 | Wyeth Corp | Carbamato y tiocarbamato biarilos ciclicos que contienen cianopirrol y metodos para preparar los mismos. |
AR049631A1 (es) | 2004-04-27 | 2006-08-23 | Wyeth Corp | Proceso de acoplamiento para la generacion de derivados reactivos de pirrol -2- carbonitrilo n- sustituidos con contenido de boro para producir biarilos |
BRPI0510260A (pt) | 2004-04-27 | 2007-10-23 | Wyeth Corp | método para purificar um composto, e, kit farmacêutico |
-
2005
- 2005-04-25 MX MXPA06012402A patent/MXPA06012402A/es active IP Right Grant
- 2005-04-25 DE DE602005007021T patent/DE602005007021D1/de active Active
- 2005-04-25 EP EP05740218A patent/EP1756095B1/de not_active Not-in-force
- 2005-04-25 US US11/113,795 patent/US7582755B2/en not_active Expired - Fee Related
- 2005-04-25 JP JP2007510902A patent/JP5108506B2/ja not_active Expired - Fee Related
- 2005-04-25 AT AT05740218T patent/ATE396189T1/de not_active IP Right Cessation
- 2005-04-25 AU AU2005238520A patent/AU2005238520B2/en not_active Ceased
- 2005-04-25 DK DK05740218T patent/DK1756095T3/da active
- 2005-04-25 CN CN200580013271XA patent/CN1946716B/zh not_active Expired - Fee Related
- 2005-04-25 PL PL05740218T patent/PL1756095T3/pl unknown
- 2005-04-25 CA CA2562160A patent/CA2562160C/en not_active Expired - Fee Related
- 2005-04-25 BR BRPI0510278-2A patent/BRPI0510278A/pt not_active IP Right Cessation
- 2005-04-25 WO PCT/US2005/014342 patent/WO2005105739A2/en not_active Application Discontinuation
- 2005-04-25 ES ES05740218T patent/ES2306140T3/es active Active
-
2009
- 2009-07-24 US US12/508,679 patent/US8003784B2/en not_active Expired - Fee Related
-
2011
- 2011-07-11 US US13/179,730 patent/US8129524B2/en not_active Expired - Fee Related
-
2012
- 2012-08-28 JP JP2012187513A patent/JP2013006853A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DK1756095T3 (da) | 2008-08-11 |
ES2306140T3 (es) | 2008-11-01 |
JP2013006853A (ja) | 2013-01-10 |
CN1946716B (zh) | 2011-12-21 |
AU2005238520A1 (en) | 2005-11-10 |
US20120016118A1 (en) | 2012-01-19 |
BRPI0510278A (pt) | 2007-10-30 |
US7582755B2 (en) | 2009-09-01 |
WO2005105739A2 (en) | 2005-11-10 |
AU2005238520B2 (en) | 2011-09-08 |
JP5108506B2 (ja) | 2012-12-26 |
EP1756095B1 (de) | 2008-05-21 |
CA2562160C (en) | 2013-05-28 |
EP1756095A2 (de) | 2007-02-28 |
PL1756095T3 (pl) | 2008-10-31 |
CN1946716A (zh) | 2007-04-11 |
US20090306371A1 (en) | 2009-12-10 |
JP2007534767A (ja) | 2007-11-29 |
US20050239779A1 (en) | 2005-10-27 |
US8003784B2 (en) | 2011-08-23 |
US8129524B2 (en) | 2012-03-06 |
CA2562160A1 (en) | 2005-11-10 |
MXPA06012402A (es) | 2007-01-17 |
WO2005105739A3 (en) | 2006-02-16 |
DE602005007021D1 (de) | 2008-07-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE396189T1 (de) | Cyanopyrrolhaltige cyclische carbamat- und thiocarbamatbiaryle und verfahren zu deren herstellung | |
EA201591774A1 (ru) | Замещенные ароматические соединения для лечения легочного фиброза, фиброза печени, фиброза кожи и фиброза сердца | |
EA201290255A1 (ru) | Способы и композиции для лечения рака | |
MX2010001773A (es) | Metodo para preparar derivados de 5-haloalquil-4,5-dihidroisoxasol . | |
EA201071264A1 (ru) | Аминодигидротиазиновые производные в качестве ингибиторов bace для лечения болезни альцгеймера | |
RS52823B (en) | NEW UNITS USEFUL FOR TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | |
NO343929B3 (no) | 1-[2-(2,4-dimetylfenylsulfanyl-fenyl]-piperazin som en forbindelse med kombinert serotoninreopptak, 5-HT3- og 5HT1A-aktivitet for behandlingen av kognitiv smerte | |
RS54199B1 (en) | PROCEDURE FOR OBTAINING INTERMEDIERS OF USEFUL USES AS OPIOID RECEPTOR MODULATORS | |
EP1740559A4 (de) | Als ?-sekretase-inhibitoren für die behandlung von alzheimer-krankheit geeignete 1,3,5-substituierte phenylderivatverbindungen | |
EA200970149A1 (ru) | Производные n-(аминогетероарил)-1h-индол-2-карбоксамидов, их получение и их применение в терапии | |
NZ746603A (en) | Agonists that enhance binding of integrin-expressing cells to integrin receptors | |
RU2502730C2 (ru) | Сульфонамидные соединения и их применение | |
HRP20130614T1 (en) | Novel pyrazole-substituted arylamides | |
DE502006002659D1 (de) | Verfahren zur herstellung von 5-(4-ä4-(5-cyano-3-indolyl)-butylü-1-piperazinyl)-benzofuran-2-carboxamid | |
HRP20090264T1 (en) | Phenyl-piperazin methanone derivatives | |
MX2010006230A (es) | Derivados de arilamida substituidos con triazol y su uso como antagonistas de receptor purinergico p2x3 y/o p2x2/3. | |
MY148988A (en) | Terphenyl derivatives for treatment of alzheimer's disease | |
FR2917969B1 (fr) | Utilisation cosmetique d'un derive d'acide imido-percarboxylique a titre d'agent desquamant | |
JP2012512863A5 (de) | ||
EA201270099A1 (ru) | Транс-4-[[(5s)-5-[[[3,5-бис(трифторметил)фенил]метил](2-метил-2h-тетразол-5-ил)амино]-2,3,4,5-тетрагидро-7,9-диметил-1h-1-бензазепин-1-ил]метил]циклогексанкарбоновая кислота | |
ATE520393T1 (de) | Verwendung von cb1-rezeptor-antagonisten zur herstellung eines arzneimittels zur behandlung von lebererkrankungen | |
EA200701676A1 (ru) | Производные дигидроимидазотиазола | |
CY1113722T1 (el) | Μεθοδος για την παρασκευη toy cinacalcet | |
CY1112638T1 (el) | Χρηση των παραγωγων ινδολιου ως ενεργοποιητες νurr-1 για την θεραπεια νοσου ραrκινsον | |
JP2011528662A5 (de) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |