CY1113722T1 - Μεθοδος για την παρασκευη toy cinacalcet - Google Patents

Μεθοδος για την παρασκευη toy cinacalcet

Info

Publication number
CY1113722T1
CY1113722T1 CY20131100175T CY131100175T CY1113722T1 CY 1113722 T1 CY1113722 T1 CY 1113722T1 CY 20131100175 T CY20131100175 T CY 20131100175T CY 131100175 T CY131100175 T CY 131100175T CY 1113722 T1 CY1113722 T1 CY 1113722T1
Authority
CY
Cyprus
Prior art keywords
cinacalcet
toy
preparing
preparation
propan
Prior art date
Application number
CY20131100175T
Other languages
English (en)
Inventor
Nicola Catozzi
Johnny Foletto
Massimiliano Forcato
Roberto Giovanetti
Giorgio Soriato
Massimo Verzini
Original Assignee
Zach System S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zach System S.P.A. filed Critical Zach System S.P.A.
Publication of CY1113722T1 publication Critical patent/CY1113722T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68—Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Μια μέθοδος για την παρασκευή της preparing N-[(IR)-1-(l-naphthyl)ethyl]-3-[3-(trifluoromethyl)-phenyl]propan-1-amine του τύπου (I) δηλαδή του Cinacalcet και των ενδιάμεσων των τύπων (V),(Va) και (Vb).
CY20131100175T 2008-10-28 2013-02-26 Μεθοδος για την παρασκευη toy cinacalcet CY1113722T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08167762 2008-10-28
EP09753056A EP2358659B1 (en) 2008-10-28 2009-10-16 Process for preparing cinacalcet

Publications (1)

Publication Number Publication Date
CY1113722T1 true CY1113722T1 (el) 2016-06-22

Family

ID=42041800

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100175T CY1113722T1 (el) 2008-10-28 2013-02-26 Μεθοδος για την παρασκευη toy cinacalcet

Country Status (15)

Country Link
US (1) US8614353B2 (el)
EP (1) EP2358659B1 (el)
JP (1) JP5514218B2 (el)
CN (1) CN102159533B (el)
AU (1) AU2009309860B2 (el)
BR (1) BRPI0919635B8 (el)
CA (1) CA2734971C (el)
CY (1) CY1113722T1 (el)
ES (1) ES2401851T3 (el)
HR (1) HRP20130154T1 (el)
IL (1) IL211307A0 (el)
PL (1) PL2358659T3 (el)
PT (1) PT2358659E (el)
SI (1) SI2358659T1 (el)
WO (1) WO2010049293A2 (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5503670B2 (ja) * 2009-02-19 2014-05-28 ザック システム エス．ピー．エー． シナカルセト塩酸塩の製造方法
ES2445532T3 (es) 2009-09-10 2014-03-03 Zach System S.P.A. Proceso para preparar cinacalcet
CZ2011770A3 (cs) * 2011-11-25 2013-01-16 Zentiva, K.S. Zpusob výroby Cinacalcetu
CN103664577B (zh) * 2012-09-06 2015-04-08 北京万生药业有限责任公司 一种西那卡塞中间体的制备方法
FR2995307A1 (fr) 2012-09-07 2014-03-14 Prod Chim Auxiliaires Et De Synthese Procede de preparation du cinacalcet et de ses sels pharmaceutiquement acceptables
CN106810452B (zh) * 2017-01-13 2018-12-28 华北水利水电大学 一种盐酸西那卡塞的制备方法
CN106831441B (zh) * 2017-01-23 2019-04-02 江苏康思尔医药科技有限公司 一种盐酸西那卡塞的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5027214B2 (ja) * 2006-04-27 2012-09-19 テバ ファーマシューティカル インダストリーズ リミティド シナカルセット塩基の調製法
MX2008000140A (es) * 2006-04-27 2009-02-23 Teva Pharma Proceso para la fabricacion de base de cinacalcet.
WO2008035381A2 (en) * 2006-09-22 2008-03-27 Ind-Swift Laboratories Limited Process for the preparation of amine derivatives as calcimimetics
WO2008117299A1 (en) * 2007-03-26 2008-10-02 Macleods Pharmaceuticals Limited Process for preparing cinacalcet hydrochloride

Also Published As

Publication number Publication date
BRPI0919635B8 (pt) 2021-05-25
BRPI0919635A8 (pt) 2017-07-11
JP5514218B2 (ja) 2014-06-04
AU2009309860B2 (en) 2015-07-23
PT2358659E (pt) 2013-03-28
ES2401851T3 (es) 2013-04-25
EP2358659B1 (en) 2012-12-26
IL211307A0 (en) 2011-04-28
HRP20130154T1 (hr) 2013-03-31
CN102159533B (zh) 2014-08-27
WO2010049293A2 (en) 2010-05-06
BRPI0919635B1 (pt) 2021-03-09
SI2358659T1 (sl) 2013-04-30
CA2734971C (en) 2017-01-31
EP2358659A2 (en) 2011-08-24
CA2734971A1 (en) 2010-05-06
CN102159533A (zh) 2011-08-17
US8614353B2 (en) 2013-12-24
BRPI0919635A2 (pt) 2015-12-01
JP2012506847A (ja) 2012-03-22
WO2010049293A3 (en) 2010-10-21
PL2358659T3 (pl) 2013-06-28
US20110207965A1 (en) 2011-08-25
AU2009309860A1 (en) 2010-05-06

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