PA8631101A1 - Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos - Google Patents

Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos

Info

Publication number
PA8631101A1
PA8631101A1 PA20058631101A PA8631101A PA8631101A1 PA 8631101 A1 PA8631101 A1 PA 8631101A1 PA 20058631101 A PA20058631101 A PA 20058631101A PA 8631101 A PA8631101 A PA 8631101A PA 8631101 A1 PA8631101 A1 PA 8631101A1
Authority
PA
Panama
Prior art keywords
boro
content
pirrol
substituted
carbonitrile
Prior art date
Application number
PA20058631101A
Other languages
English (en)
Inventor
Arkadiy Zinoviy Rubezhov
Bogdan Kazimierz Wilk
Jean Louise Helom
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8631101A1 publication Critical patent/PA8631101A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE PRESENTA UNA PREPARACION CONVENIENTE DE COMPUESTOS CON CONTENIDO DE BORO, COMPUESTOS DE PIRROLCARBONITRILO CON CONTENIDO DE BORO, COMPUESTOS DE PIRROL-2-CARBONITRILO N-SUSTITUIDOS CON CONTENIDO DE BORO Y DERIVADOS DE LOS MISMOS. LA PRESENTE INVENCION PRESENTA ASIMISMO EL USO DE ESTOS COMPUESTOS CON CONTENIDO DE BORO Y DERIVADOS DE LOS MISMOS EN REACCIONES DE ACOPLAMIENTO PARA LA PRODUCCION DE COMPUESTOS DE BIARILO.
PA20058631101A 2004-04-27 2005-04-25 Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos PA8631101A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56563604P 2004-04-27 2004-04-27
US64765605P 2005-01-27 2005-01-27

Publications (1)

Publication Number Publication Date
PA8631101A1 true PA8631101A1 (es) 2006-09-08

Family

ID=34967855

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20058631101A PA8631101A1 (es) 2004-04-27 2005-04-25 Proceso de acoplamiento para la generacion de derivados reactivos de pirrol-2-carbonitrilo n-sustituidos con contenido de boro para producir biarilos

Country Status (7)

Country Link
US (2) US7446211B2 (es)
AR (1) AR049631A1 (es)
PA (1) PA8631101A1 (es)
PE (1) PE20060331A1 (es)
SV (1) SV2005002092A (es)
TW (1) TW200604137A (es)
WO (1) WO2005105817A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005105817A2 (en) 2004-04-27 2005-11-10 Wyeth Coupling process for generating reactive boron­ containing derivatives of n-substituted pyrrole-2­ carbonitriles to produce biaryls
MXPA06012402A (es) 2004-04-27 2007-01-17 Wyeth Corp Carbamato y tiocarbamato biarilos ciclicos que contienen cianopirrol y metodos para preparar los mismos.
GT200500185A (es) * 2004-08-09 2006-04-10 Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos
US7569679B2 (en) * 2004-08-13 2009-08-04 Wyeth Tanaproget derivatives, metabolites, and uses thereof
CN101166532B (zh) 2005-04-28 2011-06-22 惠氏公司 微粒化的他那普戈特、组合物及其制备方法
CN101166736B (zh) 2005-04-28 2013-02-06 惠氏公司 他那普戈特的多晶型ⅱ
US20060246128A1 (en) 2005-04-28 2006-11-02 Wyeth Micronized tanaproget and compositions containing same
AR053595A1 (es) * 2005-04-28 2007-05-09 Wyeth Corp Forma purificada de tanaproget
PE20070220A1 (es) 2005-07-29 2007-03-19 Wyeth Corp Proceso para la sintesis de moduladores del receptor de progesterona
US20070213526A1 (en) * 2006-03-07 2007-09-13 Wyeth Purification of progesterone receptor modulators
CA2676802A1 (en) 2007-01-29 2008-08-07 Wako Pure Chemical Industries, Ltd. Reagent for organic synthesis reaction containing organic triol borate salt
US20080319204A1 (en) * 2007-06-25 2008-12-25 Wyeth Process for the synthesis of progesterone receptor modulators
CA2710293A1 (en) 2007-12-20 2009-07-02 Teva Women's Health, Inc. Dosage regimens and pharmaceutical compositions and packages for emergency contraception
EP4146626A4 (en) 2020-05-05 2024-05-29 Nuvalent, Inc. CHEMOTHERAPEUTIC AGENTS BASED ON HETEROAROMATIC MACROCYCLIC ETHERS
KR102698413B1 (ko) 2020-05-05 2024-08-26 뉴베일런트, 아이엔씨. 헤테로방향족 거대환식 에터 화학치료제
JP2024537795A (ja) 2021-10-01 2024-10-16 ヌバレント， インク． ヘテロ芳香族大環状エーテル化合物の固体形態、薬学的組成物、及び調製

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MX9206628A (es) * 1991-11-22 1993-05-01 Boehringer Ingelheim Pharma Ester de prolinaboronato y metodo para su preparacion.
EP0717740A1 (de) 1993-09-10 1996-06-26 Ciba SC Holding AG Photochrome verbindungen, verfahren und zwischenprodukte zu deren hestellung und deren verwendung
US6545108B1 (en) 1999-02-22 2003-04-08 Eastman Chemical Company Catalysts containing N-pyrrolyl substituted nitrogen donors
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WO2005105817A2 (en) 2004-04-27 2005-11-10 Wyeth Coupling process for generating reactive boron­ containing derivatives of n-substituted pyrrole-2­ carbonitriles to produce biaryls

Also Published As

Publication number Publication date
WO2005105817A2 (en) 2005-11-10
WO2005105817A3 (en) 2006-01-12
US8129523B2 (en) 2012-03-06
US20090054663A1 (en) 2009-02-26
PE20060331A1 (es) 2006-05-16
US20050272702A1 (en) 2005-12-08
SV2005002092A (es) 2005-12-13
AR049631A1 (es) 2006-08-23
TW200604137A (en) 2006-02-01
US7446211B2 (en) 2008-11-04

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