ATE446510T1 - Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine - Google Patents

Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine

Info

Publication number
ATE446510T1
ATE446510T1 AT02728619T AT02728619T ATE446510T1 AT E446510 T1 ATE446510 T1 AT E446510T1 AT 02728619 T AT02728619 T AT 02728619T AT 02728619 T AT02728619 T AT 02728619T AT E446510 T1 ATE446510 T1 AT E446510T1
Authority
AT
Austria
Prior art keywords
protein
repair
control
growth
gastrokine
Prior art date
Application number
AT02728619T
Other languages
German (de)
English (en)
Inventor
Gary Toback
Terrence E Martin
Margaret Walsh-Reitz
Original Assignee
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25234151&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE446510(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Chicago filed Critical Univ Chicago
Application granted granted Critical
Publication of ATE446510T1 publication Critical patent/ATE446510T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT02728619T 2001-03-29 2002-03-29 Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine ATE446510T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/821,726 US6734289B2 (en) 2001-03-29 2001-03-29 Gastrokines and derived peptides including inhibitors
PCT/US2002/009885 WO2002078640A2 (en) 2001-03-29 2002-03-29 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors

Publications (1)

Publication Number Publication Date
ATE446510T1 true ATE446510T1 (de) 2009-11-15

Family

ID=25234151

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02728619T ATE446510T1 (de) 2001-03-29 2002-03-29 Kontrolle des wachstums und der reparatur von gastrointestinalgewebe durch gastrokine

Country Status (10)

Country Link
US (4) US6734289B2 (cg-RX-API-DMAC7.html)
EP (2) EP1423409A4 (cg-RX-API-DMAC7.html)
JP (3) JP4295516B2 (cg-RX-API-DMAC7.html)
AT (1) ATE446510T1 (cg-RX-API-DMAC7.html)
AU (2) AU2002303199B2 (cg-RX-API-DMAC7.html)
CA (2) CA2442684C (cg-RX-API-DMAC7.html)
DE (1) DE60234103D1 (cg-RX-API-DMAC7.html)
ES (1) ES2332882T3 (cg-RX-API-DMAC7.html)
MX (2) MXPA03008861A (cg-RX-API-DMAC7.html)
WO (2) WO2002092758A2 (cg-RX-API-DMAC7.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7629317B2 (en) 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
US6734289B2 (en) * 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
DE102004047968A1 (de) * 2004-10-01 2006-04-06 B.R.A.H.M.S Ag Bestimmung von Gastrokine 1 (GKN1) als Biomarker für Entzündungen und Infektionen
US8017576B2 (en) * 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis
AU2006244080C1 (en) * 2005-05-10 2012-02-02 The University Of Chicago Use of peptides derived from the growth factor AMP-18 for the treatment of mucositis
MX2007013982A (es) * 2005-05-10 2008-03-13 Univ Chicago Uso de peptidos derivados del factor de crecimiento amp-18 para el tratamiento de la mucositis.
DK2522717T3 (da) 2006-01-04 2014-04-22 Baxter Int Oligopeptid-frie cellekulturmedier
EP2082674A1 (en) 2008-01-22 2009-07-29 Trelleborg Building Systems AB Waterproof sealing profile
EP2254464B1 (en) * 2008-02-18 2017-01-04 Medimetrics Personalized Drug Delivery B.V. Administration of drugs to a patient
WO2014099400A2 (en) * 2012-12-19 2014-06-26 The University Of Chicago Uses of a gastrokine protein
EP4421088A3 (en) * 2017-02-06 2024-12-04 Uit de Krempe IP B.V. C-peptide's interaction with elastin receptor, a blueprint for understanding vascular disease
KR102590757B1 (ko) * 2020-12-11 2023-10-17 가톨릭대학교 산학협력단 GKN1(Gastrokine 1) 특이적 항체 및 이의 용도

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476922A (en) 1987-06-24 1995-12-19 Arch Development Corporation Methods and compositions for the preparation and use of autocrine growth factors
US5135856A (en) 1987-06-24 1992-08-04 Arch Development Corp. Production of autocrine growth factors
US5102870A (en) * 1989-04-14 1992-04-07 Schering Ag Treatment and prevention of oral mucositis with growth factors
JP2938129B2 (ja) 1989-05-02 1999-08-23 武田薬品工業株式会社 虚血性腎疾患の予防・治療剤
US5644026A (en) * 1994-05-03 1997-07-01 La Jolla Cancer Research Foundation Epitaxin, a cell motility factor
JPH08231413A (ja) 1994-12-29 1996-09-10 Mochida Pharmaceut Co Ltd 臓器障害に基づく疾患の予防・治療剤
CA2218864A1 (en) 1995-04-21 1996-10-24 Tsutomu Yonehana Agent for preventing and/or treating ischemic diseases
WO2000073348A2 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Methods and compositions for inhibiting neoplastic cell growth
JP3681405B2 (ja) 1997-02-21 2005-08-10 タカラバイオ株式会社 癌関連遺伝子
US7074897B2 (en) * 1997-06-16 2006-07-11 Genentech, Inc. Pro943 polypeptides
EP1012261A4 (en) * 1997-08-06 2003-04-02 Inst Genetics Llc SECRETED PROTEINS AND POLYNUCLEOTIDES ENCODING THEM
WO2000000610A2 (en) * 1998-06-26 2000-01-06 Incyte Pharmaceuticals, Inc. Human signal peptide-containing proteins
WO2000043781A2 (en) 1999-01-21 2000-07-27 Metamorphix, Inc. Growth differentiation factor inhibitors and uses therefor
CA2383254A1 (en) * 1999-06-02 2000-12-07 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7629317B2 (en) * 2001-03-29 2009-12-08 The University Of Chicago Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
US6734289B2 (en) 2001-03-29 2004-05-11 The University Of Chicago Gastrokines and derived peptides including inhibitors
US8017576B2 (en) * 2005-05-10 2011-09-13 The University Of Chicago Methods and compositions to treat mucositis

Also Published As

Publication number Publication date
WO2002092758A3 (en) 2004-04-01
WO2002092758A8 (en) 2003-02-20
AU2002258663B2 (en) 2008-02-21
MXPA03008861A (es) 2004-10-15
JP4281947B2 (ja) 2009-06-17
US8278269B2 (en) 2012-10-02
WO2002092758A9 (en) 2004-06-24
AU2002303199B2 (en) 2008-03-13
US8791068B2 (en) 2014-07-29
JP2004537284A (ja) 2004-12-16
US7557083B2 (en) 2009-07-07
US20050065328A1 (en) 2005-03-24
CA2442684C (en) 2013-11-19
MXPA03008855A (es) 2004-12-06
EP1415154B1 (en) 2009-10-21
JP2004532037A (ja) 2004-10-21
EP1423409A4 (en) 2005-12-07
JP4295516B2 (ja) 2009-07-15
EP1415154A4 (en) 2004-12-22
CA2442684A1 (en) 2002-10-10
DE60234103D1 (de) 2009-12-03
WO2002078640A2 (en) 2002-10-10
WO2002078640A3 (en) 2004-03-04
JP2007217422A (ja) 2007-08-30
EP1423409A2 (en) 2004-06-02
EP1415154A2 (en) 2004-05-06
US20130086701A1 (en) 2013-04-04
WO2002092758A2 (en) 2002-11-21
US20030017548A1 (en) 2003-01-23
US20050054564A1 (en) 2005-03-10
CA2442635A1 (en) 2002-11-21
US6734289B2 (en) 2004-05-11
ES2332882T3 (es) 2010-02-15

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