ATE445227T1 - Methoden und apparat für die massenspektrometrie - Google Patents
Methoden und apparat für die massenspektrometrieInfo
- Publication number
- ATE445227T1 ATE445227T1 AT05025116T AT05025116T ATE445227T1 AT E445227 T1 ATE445227 T1 AT E445227T1 AT 05025116 T AT05025116 T AT 05025116T AT 05025116 T AT05025116 T AT 05025116T AT E445227 T1 ATE445227 T1 AT E445227T1
- Authority
- AT
- Austria
- Prior art keywords
- ions
- parent
- daughter
- mode
- mass spectra
- Prior art date
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
- H01J49/4205—Device types
- H01J49/421—Mass filters, i.e. deviating unwanted ions without trapping
- H01J49/4215—Quadrupole mass filters
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0014062A GB0014062D0 (en) | 2000-06-09 | 2000-06-09 | Methods and apparatus for tandem mass spectrometry |
GB0101048A GB0101048D0 (en) | 2001-01-15 | 2001-01-15 | Methods and apparatus for tandem mass spectrometry |
GB0105227A GB2364168B (en) | 2000-06-09 | 2001-03-02 | Methods and apparatus for mass spectrometry |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE445227T1 true ATE445227T1 (de) | 2009-10-15 |
Family
ID=26244455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05025116T ATE445227T1 (de) | 2000-06-09 | 2001-06-11 | Methoden und apparat für die massenspektrometrie |
Country Status (6)
Country | Link |
---|---|
US (1) | US6586727B2 (de) |
EP (2) | EP2299469B1 (de) |
JP (1) | JP5154511B2 (de) |
AT (1) | ATE445227T1 (de) |
DE (2) | DE60140150D1 (de) |
GB (1) | GB2364168B (de) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020115056A1 (en) | 2000-12-26 | 2002-08-22 | Goodlett David R. | Rapid and quantitative proteome analysis and related methods |
US7038197B2 (en) * | 2001-04-03 | 2006-05-02 | Micromass Limited | Mass spectrometer and method of mass spectrometry |
US6777671B2 (en) * | 2001-04-10 | 2004-08-17 | Science & Engineering Services, Inc. | Time-of-flight/ion trap mass spectrometer, a method, and a computer program product to use the same |
AU2003218649B2 (en) * | 2002-02-28 | 2007-09-06 | Metanomics Gmbh & Co. Kgaa | Mass spectrometry method for analysing mixtures of substances |
WO2003094197A1 (en) * | 2002-04-29 | 2003-11-13 | Mds Inc., Doing Business As Mds Sciex | Broad ion fragmentation coverage in mass spectrometry by varying the collision energy |
US6770871B1 (en) * | 2002-05-31 | 2004-08-03 | Michrom Bioresources, Inc. | Two-dimensional tandem mass spectrometry |
GB0305796D0 (en) | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
US6987263B2 (en) * | 2002-12-13 | 2006-01-17 | Nanostream, Inc. | High throughput systems and methods for parallel sample analysis |
US20060076482A1 (en) * | 2002-12-13 | 2006-04-13 | Hobbs Steven E | High throughput systems and methods for parallel sample analysis |
JP3816883B2 (ja) * | 2003-03-06 | 2006-08-30 | 株式会社日立ハイテクノロジーズ | 液体クロマトグラフ質量分析装置 |
US7041968B2 (en) * | 2003-03-20 | 2006-05-09 | Science & Technology Corporation @ Unm | Distance of flight spectrometer for MS and simultaneous scanless MS/MS |
CA2518568C (en) * | 2003-04-09 | 2012-09-25 | Mds Inc., Doing Business Through Its Mds Sciex Division | Dynamic background signal exclusion in chromatography/mass spectrometry data-dependent, data acquisition |
US20050227251A1 (en) | 2003-10-23 | 2005-10-13 | Robert Darnell | Method of purifying RNA binding protein-RNA complexes |
US20060186028A1 (en) * | 2004-02-06 | 2006-08-24 | Micromass Uk Limited | Mass spectrometer |
US20070258861A1 (en) * | 2004-06-15 | 2007-11-08 | Barket Dennis Jr | Analytical Instruments, Assemblies, and Methods |
GB0416288D0 (en) | 2004-07-21 | 2004-08-25 | Micromass Ltd | Mass spectrometer |
US8680461B2 (en) | 2005-04-25 | 2014-03-25 | Griffin Analytical Technologies, L.L.C. | Analytical instrumentation, apparatuses, and methods |
US7417223B2 (en) * | 2005-10-28 | 2008-08-26 | Mds Inc. | Method, system and computer software product for specific identification of reaction pairs associated by specific neutral differences |
GB2432712B (en) * | 2005-11-23 | 2007-12-27 | Micromass Ltd | Mass spectrometer |
WO2007079589A1 (en) * | 2006-01-11 | 2007-07-19 | Mds Inc., Doing Business Through Its Mds Sciex Division | Fragmenting ions in mass spectrometry |
DE112007000931B4 (de) | 2006-04-13 | 2014-05-22 | Thermo Fisher Scientific (Bremen) Gmbh | Ionenenergiestreuungsreduzierung für ein Massenspektrometer |
GB0607542D0 (en) * | 2006-04-13 | 2006-05-24 | Thermo Finnigan Llc | Mass spectrometer |
GB0609253D0 (en) | 2006-05-10 | 2006-06-21 | Micromass Ltd | Mass spectrometer |
WO2007132502A1 (ja) * | 2006-05-11 | 2007-11-22 | Shimadzu Corporation | 質量分析装置用データ処理装置 |
US7992424B1 (en) | 2006-09-14 | 2011-08-09 | Griffin Analytical Technologies, L.L.C. | Analytical instrumentation and sample analysis methods |
US7511267B2 (en) * | 2006-11-10 | 2009-03-31 | Thermo Finnigan Llc | Data-dependent accurate mass neutral loss analysis |
EP1933366B1 (de) * | 2006-12-14 | 2019-06-12 | Tofwerk AG | Vorrichtung zur Massenanalyse von Ionen |
EP1933365A1 (de) * | 2006-12-14 | 2008-06-18 | Tofwerk AG | Vorrichtung zur Massenanalyse von Ionen |
EP1968100B1 (de) * | 2007-03-08 | 2014-04-30 | Tofwerk AG | Ionenführungskammer |
CA2718535C (en) * | 2008-03-20 | 2017-06-06 | Dh Technologies Development Pte. Ltd. | Systems and methods for analyzing substances using a mass spectrometer |
DE102008025972B4 (de) * | 2008-05-30 | 2018-11-29 | Bruker Daltonik Gmbh | Verfahren zur Messung der Mobilität massenspektrometrisch ausgewählter Ionensorten |
WO2010032276A1 (ja) * | 2008-09-16 | 2010-03-25 | 株式会社島津製作所 | 飛行時間型質量分析装置 |
WO2010135829A1 (en) * | 2009-05-27 | 2010-12-02 | Dh Technologies Development Pte. Ltd. | Method for high efficiency tandem mass spectrometry |
GB0915474D0 (en) | 2009-09-04 | 2009-10-07 | Micromass Ltd | Multiple reaction monitoring with a time-of-flight based mass spectrometer |
GB0919870D0 (en) * | 2009-11-13 | 2009-12-30 | Micromass Ltd | A method to detect and quantitatively profile organic species using a mass spectrometer |
JP5314603B2 (ja) * | 2010-01-15 | 2013-10-16 | 日本電子株式会社 | 飛行時間型質量分析装置 |
DE102011017084B4 (de) | 2010-04-14 | 2020-07-09 | Wisconsin Alumni Research Foundation | Massenspektrometriedaten-Erfassungsmodus zur Erzielung einer zuverlässigeren Proteinquantifizierung |
US8809770B2 (en) * | 2010-09-15 | 2014-08-19 | Dh Technologies Development Pte. Ltd. | Data independent acquisition of product ion spectra and reference spectra library matching |
DE102011053684B4 (de) | 2010-09-17 | 2019-03-28 | Wisconsin Alumni Research Foundation | Verfahren zur Durchführung von strahlformstossaktivierter Dissoziation im bereits bestehenden Ioneninjektionspfad eines Massenspektrometers |
WO2012090046A1 (en) | 2010-12-29 | 2012-07-05 | Dh Technologies Development Pte. Ltd. | Method for triggering dependent spectra for data acquisition |
GB201104225D0 (en) * | 2011-03-14 | 2011-04-27 | Micromass Ltd | Pre scan for mass to charge ratio range |
JP5967078B2 (ja) * | 2011-04-04 | 2016-08-10 | 株式会社島津製作所 | 質量分析装置及び質量分析方法 |
US9040903B2 (en) | 2011-04-04 | 2015-05-26 | Wisconsin Alumni Research Foundation | Precursor selection using an artificial intelligence algorithm increases proteomic sample coverage and reproducibility |
GB201106689D0 (en) * | 2011-04-20 | 2011-06-01 | Micromass Ltd | Function switching with fast asynchronous acquisition |
CN103582929B (zh) * | 2011-06-03 | 2016-10-19 | Dh科技发展私人贸易有限公司 | 使用可变窗口带通过滤从测量扫描移除离子以改善扫描内动态范围 |
GB201116065D0 (en) | 2011-09-16 | 2011-11-02 | Micromass Ltd | Encoding of precursor ion beam to aid product ion assignment |
WO2013081581A1 (en) * | 2011-11-29 | 2013-06-06 | Thermo Finnigan Llc | Method for automated checking and adjustment of mass spectrometer calibration |
GB201122178D0 (en) | 2011-12-22 | 2012-02-01 | Thermo Fisher Scient Bremen | Method of tandem mass spectrometry |
GB2497948A (en) | 2011-12-22 | 2013-07-03 | Thermo Fisher Scient Bremen | Collision cell for tandem mass spectrometry |
US9048072B2 (en) * | 2012-03-12 | 2015-06-02 | Micromass Uk Limited | Method of mass spectrometry and a mass spectrometer |
JP2015512523A (ja) * | 2012-04-05 | 2015-04-27 | マイクロマス ユーケー リミテッド | Ecdまたはetdフラグメンテーションを用いるms/ms分析 |
EP2741224A1 (de) * | 2012-11-20 | 2014-06-11 | Thermo Finnigan LLC | Verfahren zur Erzeugung von lokalen massenspektrometrischen Bibliotheken zur Interpretation überlagerter Massenspektren |
EP3283877A4 (de) | 2015-04-14 | 2018-10-31 | Waters Technologies Corporation | Strukturaufklärung von isotopisch markierten analyten |
WO2016196181A1 (en) * | 2015-05-29 | 2016-12-08 | Waters Technologies Corporation | Mass spectrometry with quadrupole and ion mobility separation capabilities |
GB2565238A (en) | 2015-06-09 | 2019-02-06 | Waters Technologies Corp | Molecular diagnostics in personalized dermatology, dermatopathology and cosmetics |
GB2544834A (en) | 2015-06-09 | 2017-05-31 | Waters Technologies Corp | Profile diagnositcs in personalized dermatology, dermatopathology and cosmetics |
WO2017060991A1 (ja) * | 2015-10-07 | 2017-04-13 | 株式会社島津製作所 | タンデム型質量分析装置 |
JP2019535007A (ja) | 2016-09-27 | 2019-12-05 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 複合試料のためのマルチ特性モニタリング法 |
GB2585372B (en) | 2019-07-04 | 2022-03-02 | Thermo Fisher Scient Bremen Gmbh | Methods and apparatus for mass spectrometry |
CN110455907B (zh) * | 2019-07-04 | 2022-04-19 | 昆山禾信质谱技术有限公司 | 基于飞行时间质量分析器的串联质谱数据分析方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2120007B (en) | 1982-04-16 | 1985-09-11 | Univ Sherbrooke | Isotope determination by mass spectrometry |
US5073713A (en) * | 1990-05-29 | 1991-12-17 | Battelle Memorial Institute | Detection method for dissociation of multiple-charged ions |
GB2250632B (en) * | 1990-10-18 | 1994-11-23 | Unisearch Ltd | Tandem mass spectrometry systems based on time-of-flight analyser |
US5182451A (en) * | 1991-04-30 | 1993-01-26 | Finnigan Corporation | Method of operating an ion trap mass spectrometer in a high resolution mode |
GB9510052D0 (en) * | 1995-05-18 | 1995-07-12 | Fisons Plc | Mass spectrometer |
GB9518429D0 (en) * | 1995-09-08 | 1995-11-08 | Pharmacia Biosensor | A rapid method for providing kinetic and structural data in molecular interaction analysis |
US6323482B1 (en) * | 1997-06-02 | 2001-11-27 | Advanced Research And Technology Institute, Inc. | Ion mobility and mass spectrometer |
GB9717926D0 (en) | 1997-08-22 | 1997-10-29 | Micromass Ltd | Methods and apparatus for tandem mass spectrometry |
CA2227806C (en) * | 1998-01-23 | 2006-07-18 | University Of Manitoba | Spectrometer provided with pulsed ion source and transmission device to damp ion motion and method of use |
WO1999038193A1 (en) * | 1998-01-23 | 1999-07-29 | Analytica Of Branford, Inc. | Mass spectrometry with multipole ion guide |
JP3405919B2 (ja) * | 1998-04-01 | 2003-05-12 | 株式会社日立製作所 | 大気圧イオン化質量分析計 |
JP4540230B2 (ja) * | 1998-09-25 | 2010-09-08 | オレゴン州 | タンデム飛行時間質量分析計 |
CA2255122C (en) | 1998-12-04 | 2007-10-09 | Mds Inc. | Improvements in ms/ms methods for a quadrupole/time of flight tandem mass spectrometer |
CA2340150C (en) * | 2000-06-09 | 2005-11-22 | Micromass Limited | Methods and apparatus for mass spectrometry |
-
2001
- 2001-03-02 US US09/796,544 patent/US6586727B2/en not_active Expired - Lifetime
- 2001-03-02 GB GB0105227A patent/GB2364168B/en not_active Expired - Lifetime
- 2001-06-11 DE DE60140150T patent/DE60140150D1/de not_active Expired - Lifetime
- 2001-06-11 EP EP10182678.2A patent/EP2299469B1/de not_active Expired - Lifetime
- 2001-06-11 DE DE20122885U patent/DE20122885U1/de not_active Expired - Lifetime
- 2001-06-11 EP EP09002434.0A patent/EP2056334B1/de not_active Expired - Lifetime
- 2001-06-11 AT AT05025116T patent/ATE445227T1/de not_active IP Right Cessation
-
2009
- 2009-06-12 JP JP2009141208A patent/JP5154511B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP2056334B1 (de) | 2016-02-24 |
US20010052569A1 (en) | 2001-12-20 |
EP2299469B1 (de) | 2016-01-06 |
EP2056334A3 (de) | 2009-12-02 |
EP2299469A1 (de) | 2011-03-23 |
US6586727B2 (en) | 2003-07-01 |
GB2364168B (en) | 2002-06-26 |
GB2364168A (en) | 2002-01-16 |
DE60140150D1 (de) | 2009-11-19 |
JP5154511B2 (ja) | 2013-02-27 |
EP2056334A2 (de) | 2009-05-06 |
JP2009258116A (ja) | 2009-11-05 |
DE20122885U1 (de) | 2008-12-24 |
GB0105227D0 (en) | 2001-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |