ATE441648T1 - Tetrapyrrol-macrocyclen als photodynamische mittel - Google Patents

Tetrapyrrol-macrocyclen als photodynamische mittel

Info

Publication number
ATE441648T1
ATE441648T1 AT03734703T AT03734703T ATE441648T1 AT E441648 T1 ATE441648 T1 AT E441648T1 AT 03734703 T AT03734703 T AT 03734703T AT 03734703 T AT03734703 T AT 03734703T AT E441648 T1 ATE441648 T1 AT E441648T1
Authority
AT
Austria
Prior art keywords
tetrapyrrol
macrocycles
hydrogen
positions
photodynamic agents
Prior art date
Application number
AT03734703T
Other languages
English (en)
Inventor
Goncalves Antonio Rocha
Marta Pineiro
Armenio Serra
Original Assignee
Cipan Comp Ind Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipan Comp Ind Prod filed Critical Cipan Comp Ind Prod
Application granted granted Critical
Publication of ATE441648T1 publication Critical patent/ATE441648T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Resins (AREA)
  • Indole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT03734703T 2002-02-01 2003-01-28 Tetrapyrrol-macrocyclen als photodynamische mittel ATE441648T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT102721A PT102721B (pt) 2002-02-01 2002-02-01 Compostos macrocíclicos tetrapirrólicos com rendimento quântico de oxigénio singuleto adequado à terapia fotodinâmica e processos para a sua preparação
PCT/EP2003/000829 WO2003064427A1 (en) 2002-02-01 2003-01-28 Tetrapyrrolic macrocycles as photodynamic agents

Publications (1)

Publication Number Publication Date
ATE441648T1 true ATE441648T1 (de) 2009-09-15

Family

ID=27656540

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03734703T ATE441648T1 (de) 2002-02-01 2003-01-28 Tetrapyrrol-macrocyclen als photodynamische mittel

Country Status (6)

Country Link
EP (1) EP1472259B1 (de)
AT (1) ATE441648T1 (de)
DE (1) DE60329075D1 (de)
ES (1) ES2333006T3 (de)
PT (1) PT102721B (de)
WO (1) WO2003064427A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
WO2011161065A1 (en) 2010-06-25 2011-12-29 Fundação Padre Antonio Vieira Macrocyclic tetrapyrrolic compound of the family of porphyrins, chlorins and bacteriochlorins as photosensitizers for photodynamic therapy
RU2538261C2 (ru) * 2013-03-22 2015-01-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Гетерогенный сенсибилизатор и способ фотообеззараживания воды
WO2017051435A1 (en) * 2015-09-22 2017-03-30 Council Of Scientific And Industrial Research Chlorin based compounds, a process for preparation thereof and use as photodynamic therapeutic agents and fluorescent probes
RU2771237C1 (ru) * 2021-06-04 2022-04-28 федеральное государственное автоносное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» Сенсибилизатор для фотодинамического разрушения опухолевых клеток

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE123749T1 (de) * 1987-04-17 1995-06-15 David H Dolphin Porphyrine, verfahren zu deren herstellung und verwendungen.
GB8805849D0 (en) * 1988-03-11 1988-04-13 Efamol Holdings Porphyrins & cancer treatment
CZ278391B6 (en) * 1990-08-08 1993-12-15 Ustav Organicke Chemie A Bioch Substituted 5,15-diphenylporphyrins and process for preparing thereof
EP0871629A4 (de) * 1995-06-20 2001-11-21 Miravant Pharm Inc Effiziente funktionalisierung von porphyrinderivaten
AU4278400A (en) * 1999-04-14 2000-11-14 University Of British Columbia, The Improved beta,beta,-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
GB0001455D0 (en) * 2000-01-21 2000-03-15 Scotia Holdings Plc Porphyrins and related compounds
GB0005855D0 (en) * 2000-03-10 2000-05-03 Scotia Holdings Plc Compounds for pdt
AU3567500A (en) * 2000-03-30 2001-10-15 Hugo Oppelaar Photodynamic therapy compounds
JP3385468B2 (ja) * 2000-06-12 2003-03-10 科学技術振興事業団 新規な拡張ポルフィリン及び拡張ポルフィリンの合成法

Also Published As

Publication number Publication date
PT102721B (pt) 2011-01-24
WO2003064427A1 (en) 2003-08-07
DE60329075D1 (en) 2009-10-15
EP1472259B1 (de) 2009-09-02
PT102721A (pt) 2003-08-29
ES2333006T3 (es) 2010-02-16
EP1472259A1 (de) 2004-11-03

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