ATE438400T1 - Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittel - Google Patents
Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittelInfo
- Publication number
- ATE438400T1 ATE438400T1 AT05708696T AT05708696T ATE438400T1 AT E438400 T1 ATE438400 T1 AT E438400T1 AT 05708696 T AT05708696 T AT 05708696T AT 05708696 T AT05708696 T AT 05708696T AT E438400 T1 ATE438400 T1 AT E438400T1
- Authority
- AT
- Austria
- Prior art keywords
- antibacterial agents
- imidazopyridine
- formula
- compounds
- imidazopyrimidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Surgery (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55451004P | 2004-03-19 | 2004-03-19 | |
US63077704P | 2004-11-23 | 2004-11-23 | |
PCT/IB2005/000596 WO2005089763A1 (en) | 2004-03-19 | 2005-03-07 | Imidazopyridine and imidazopyrimidine derivatives as antibacterial agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE438400T1 true ATE438400T1 (de) | 2009-08-15 |
Family
ID=34961036
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05708696T ATE438400T1 (de) | 2004-03-19 | 2005-03-07 | Imidazopyridin- und imidazopyrimidin-derivate als antibakterielle mittel |
Country Status (10)
Country | Link |
---|---|
US (2) | US7563788B2 (de) |
EP (1) | EP1737459B1 (de) |
JP (1) | JP2007529496A (de) |
AT (1) | ATE438400T1 (de) |
BR (1) | BRPI0507653A (de) |
CA (1) | CA2559229A1 (de) |
DE (1) | DE602005015833D1 (de) |
DK (1) | DK1737459T3 (de) |
ES (1) | ES2328047T3 (de) |
WO (1) | WO2005089763A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1608319A4 (de) | 2003-04-03 | 2007-02-28 | Univ California | Verbesserte hemmer für lösliche epoxidhydrolase |
JP2007532484A (ja) | 2004-03-16 | 2007-11-15 | ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 可溶性エポキシド加水分解酵素の阻害剤およびエポキシエイコサノイドを用いて腎症を緩和する方法 |
ZA200703613B (en) | 2004-10-20 | 2009-05-27 | Univ California | Improved inhibitors for the soluble epoxide hydrolase |
PE20070978A1 (es) * | 2006-02-14 | 2007-11-15 | Novartis Ag | COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks) |
TW200808723A (en) | 2006-03-13 | 2008-02-16 | Univ California | Conformationally restricted urea inhibitors of soluble epoxide hydrolase |
WO2008015196A1 (en) * | 2006-07-31 | 2008-02-07 | Nycomed Gmbh | 5-,7-bis-substituted imidazo[1,2-a]pyridines |
EA201300152A1 (ru) | 2006-11-27 | 2013-07-30 | Х. Лундбекк А/С | Гетероариламидные производные |
JP2010523668A (ja) | 2007-04-10 | 2010-07-15 | ハー・ルンドベック・アクチエゼルスカベット | P2x7拮抗薬としてのヘテロアリールアミド類似体 |
KR20100049073A (ko) * | 2007-07-18 | 2010-05-11 | 노파르티스 아게 | 비시클릭 헤테로아릴 화합물 및 키나제 억제제로서의 그의 용도 |
US8431608B2 (en) | 2007-08-17 | 2013-04-30 | Icagen Inc. | Heterocycles as potassium channel modulators |
JP5463287B2 (ja) * | 2007-08-17 | 2014-04-09 | アイカジェン, インコーポレイテッド | カリウムチャネル調節物質としての複素環 |
EP2277881A4 (de) * | 2008-04-18 | 2011-09-07 | Shionogi & Co | Heterocyclische verbindung mit inhibierender wirkung auf p13k |
US8575337B2 (en) | 2008-06-24 | 2013-11-05 | Research Foundation Itsuu Laboratory | Oxazolidinone derivative having fused ring |
EP2166009A1 (de) * | 2008-09-23 | 2010-03-24 | Genkyo Tex Sa | Pyrazolopyridinderivate als NADPH-Oxidasehemmer |
US9296693B2 (en) | 2010-01-29 | 2016-03-29 | The Regents Of The University Of California | Acyl piperidine inhibitors of soluble epoxide hydrolase |
PL2547678T3 (pl) * | 2010-03-18 | 2016-10-31 | Związki przeciwzapalne | |
CA2793975A1 (en) | 2010-03-31 | 2011-10-10 | Actelion Pharmaceuticals Ltd | Antibacterial isoquinolin-3-ylurea derivatives |
WO2012018662A2 (en) | 2010-08-03 | 2012-02-09 | Schering Corporation | Fused-imidazoyl compounds useful as antimicrobial agents |
WO2012018665A1 (en) * | 2010-08-03 | 2012-02-09 | Schering Corporation | Fused-imidazoyl compounds useful as antimicrobial agents |
AR088729A1 (es) | 2011-03-29 | 2014-07-02 | Actelion Pharmaceuticals Ltd | Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica |
GB201416754D0 (en) | 2014-09-23 | 2014-11-05 | Mission Therapeutics Ltd | Novel compounds |
KR101987994B1 (ko) * | 2015-01-28 | 2019-06-11 | 제이엔 테라퓨틱스 | 치환된 이미다조[1,2-a]피리딘-2-일아민 화합물, 및 약학 조성물 및 이의 사용 방법 |
US10836742B2 (en) | 2015-08-11 | 2020-11-17 | Neomed Institute | N-substituted bicyclic lactams, their preparation and their use as pharmaceuticals |
CN108290856A (zh) | 2015-08-11 | 2018-07-17 | 尼奥迈德研究所 | 芳基-取代的二氢喹诺酮、它们的制备和它们作为药物的用途 |
IL257340B2 (en) | 2015-08-12 | 2023-10-01 | Neomed Inst | Converted benzaimidazoles, methods for their preparation and use as pharmaceuticals |
WO2017066876A1 (en) | 2015-10-21 | 2017-04-27 | Neomed Institute | Substituted imidazopyridines, their preparation and their use as pharmaceuticals |
WO2017127930A1 (en) | 2016-01-28 | 2017-08-03 | Neomed Institute | Substituted [1,2,4]triazolo[4,3-a]pyridines, their preparation and their use as pharmaceuticals |
CN110248938A (zh) | 2016-11-23 | 2019-09-17 | 拜耳作物科学股份公司 | 用作农药的2-[3-(烷基磺酰基)-2h-吲唑-2-基]-3h-咪唑并[4,5-b]吡啶衍生物和类似化合物 |
JPWO2018174288A1 (ja) | 2017-03-24 | 2020-01-23 | 大正製薬株式会社 | 2(1h)−キノリノン誘導体 |
US11673891B2 (en) | 2017-11-14 | 2023-06-13 | Dana-Farber Cancer Institute, Inc. | Imidazopyrimidine compounds and uses thereof |
EP3710007A4 (de) | 2017-11-14 | 2021-12-15 | Children's Medical Center Corporation | Verwendung von imidazopyrimidin zur modulation der menschlichen immunantwort |
IL303087B1 (en) | 2018-02-27 | 2024-08-01 | Incyte Corp | Midazopyrimidines and triazolopyrimidines as A2A /A2B inhibitors |
CA3100731A1 (en) | 2018-05-18 | 2019-11-21 | Incyte Corporation | Fused pyrimidine derivatives as a2a / a2b inhibitors |
CN113166153B (zh) | 2018-07-05 | 2024-11-01 | 因赛特公司 | 作为a2a/a2b抑制剂的稠合吡嗪衍生物 |
TWI829857B (zh) | 2019-01-29 | 2024-01-21 | 美商英塞特公司 | 作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶 |
WO2022032644A1 (zh) * | 2020-08-14 | 2022-02-17 | 上海复旦张江生物医药股份有限公司 | 一种取代的咪唑并[1,2-a]吡啶-2-基酰胺化合物的制备方法及其中间体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4096264A (en) * | 1975-12-09 | 1978-06-20 | Merck & Co., Inc. | Certain substituted imidazo [1,2-a] pyridines |
US4105767A (en) * | 1977-03-28 | 1978-08-08 | Merck & Co., Inc. | Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group |
US4250174A (en) * | 1979-05-02 | 1981-02-10 | Merck & Co., Inc. | 3-Substituted imidazo [1,2-A] pyridines |
-
2005
- 2005-03-07 AT AT05708696T patent/ATE438400T1/de not_active IP Right Cessation
- 2005-03-07 EP EP05708696A patent/EP1737459B1/de not_active Not-in-force
- 2005-03-07 DK DK05708696T patent/DK1737459T3/da active
- 2005-03-07 CA CA002559229A patent/CA2559229A1/en not_active Abandoned
- 2005-03-07 WO PCT/IB2005/000596 patent/WO2005089763A1/en not_active Application Discontinuation
- 2005-03-07 US US10/598,841 patent/US7563788B2/en not_active Expired - Fee Related
- 2005-03-07 BR BRPI0507653-6A patent/BRPI0507653A/pt not_active IP Right Cessation
- 2005-03-07 ES ES05708696T patent/ES2328047T3/es active Active
- 2005-03-07 DE DE602005015833T patent/DE602005015833D1/de active Active
- 2005-03-07 JP JP2007503429A patent/JP2007529496A/ja not_active Withdrawn
-
2009
- 2009-06-15 US US12/484,263 patent/US20090275577A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2007529496A (ja) | 2007-10-25 |
US20070191394A1 (en) | 2007-08-16 |
EP1737459A1 (de) | 2007-01-03 |
CA2559229A1 (en) | 2005-09-29 |
DK1737459T3 (da) | 2009-10-26 |
ES2328047T3 (es) | 2009-11-06 |
US20090275577A1 (en) | 2009-11-05 |
US7563788B2 (en) | 2009-07-21 |
EP1737459B1 (de) | 2009-08-05 |
BRPI0507653A (pt) | 2007-07-10 |
WO2005089763A1 (en) | 2005-09-29 |
DE602005015833D1 (de) | 2009-09-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |