ATE437652T1 - Verwendung von hmgb1 zur aktivierung dendritischer zellen - Google Patents
Verwendung von hmgb1 zur aktivierung dendritischer zellenInfo
- Publication number
- ATE437652T1 ATE437652T1 AT02775057T AT02775057T ATE437652T1 AT E437652 T1 ATE437652 T1 AT E437652T1 AT 02775057 T AT02775057 T AT 02775057T AT 02775057 T AT02775057 T AT 02775057T AT E437652 T1 ATE437652 T1 AT E437652T1
- Authority
- AT
- Austria
- Prior art keywords
- hmgb1
- dendritic cells
- activate dendritic
- activate
- apc
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001MI001986A ITMI20011986A1 (it) | 2001-09-25 | 2001-09-25 | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
PCT/IB2002/004080 WO2003026691A2 (en) | 2001-09-25 | 2002-09-25 | Use of hmgb1 for the activation of dendritic cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE437652T1 true ATE437652T1 (de) | 2009-08-15 |
Family
ID=11448420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02775057T ATE437652T1 (de) | 2001-09-25 | 2002-09-25 | Verwendung von hmgb1 zur aktivierung dendritischer zellen |
Country Status (9)
Country | Link |
---|---|
US (1) | US20040242481A1 (de) |
EP (1) | EP1432441B1 (de) |
JP (1) | JP2005508913A (de) |
AT (1) | ATE437652T1 (de) |
AU (1) | AU2002341266B2 (de) |
CA (1) | CA2461091A1 (de) |
DE (1) | DE60233147D1 (de) |
IT (1) | ITMI20011986A1 (de) |
WO (1) | WO2003026691A2 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050112121A1 (en) * | 1992-04-30 | 2005-05-26 | Yale University | Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids |
GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
EP1899376A2 (de) | 2005-06-16 | 2008-03-19 | The Feinstein Institute for Medical Research | Antikörper gegen hmgb 1 und fragmente davon |
WO2007130725A2 (en) * | 2006-02-06 | 2007-11-15 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of hmgb1 for protection against ischemia reperfusion injury |
CA2636788A1 (en) * | 2006-10-30 | 2008-05-08 | Genomix Co., Ltd. | Hmgb protein for use in promoting tissue regeneration |
TW200900077A (en) | 2007-02-15 | 2009-01-01 | Univ Kyushu Nat Univ Corp | Therapeutic agent for interstitial pulmonary disease comprising anti-HMGB-1 antibody |
TW200902063A (en) | 2007-02-15 | 2009-01-16 | Univ Kumamoto | Therapeutic agent comprising antibody capable of specifically binding to human hmgb-1 as active ingredient |
WO2008099917A1 (ja) * | 2007-02-15 | 2008-08-21 | Fukuoka University | 抗hmgb-1抗体を含む臓器移植拒絶抑制剤 |
HUE047164T2 (hu) | 2007-11-01 | 2020-04-28 | Univ Arkansas | Kompozíciók és eljárások eimeria elleni immunválasz fokozására |
JP5814549B2 (ja) * | 2008-04-30 | 2015-11-17 | 株式会社ジェノミックス | 損傷組織の機能的再生促進医薬 |
JP5676253B2 (ja) | 2008-04-30 | 2015-02-25 | 株式会社ジェノミックス | 生体内機能的細胞の高効率採取法 |
RU2519714C2 (ru) * | 2008-04-30 | 2014-06-20 | Дженомикс Ко., Лтд. | Средство для вовлечения происходящей из костного мозга плюрипотентной стволовой клетки в периферический кровоток |
KR20120135190A (ko) | 2009-10-28 | 2012-12-12 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 골수 간엽계 및/또는 다능성 줄기세포의 혈중 동원(動員)에 의한 조직 재생 촉진제 |
CA2787661C (en) | 2010-01-21 | 2021-10-12 | The Board Of Trustees Of The University Of Arkansas | Vaccine vectors and methods of enhancing immune responses |
US8999291B2 (en) | 2010-03-29 | 2015-04-07 | University Of Southern California | Compositions and methods for the removal of biofilms |
EP3556397A1 (de) * | 2010-06-09 | 2019-10-23 | The Board of Trustees of the University of Arkansas | Impfstoff und verfahren zur linderung einer campylobacter-infektion |
US20120128701A1 (en) * | 2010-09-09 | 2012-05-24 | Nationwide Children's Hospital, Inc. | Compositions and methods for the removal of biofilms |
EP2703487B1 (de) | 2011-04-26 | 2018-06-27 | Genomix Co., Ltd. | Peptide zur induktion der regenerierung von gewebe und verwendung davon |
US9244074B2 (en) | 2011-06-07 | 2016-01-26 | University Of Hawaii | Biomarker of asbestos exposure and mesothelioma |
US9561274B2 (en) | 2011-06-07 | 2017-02-07 | University Of Hawaii | Treatment and prevention of cancer with HMGB1 antagonists |
SG11201503236RA (en) | 2012-10-25 | 2015-06-29 | Genomix Co Ltd | Novel method for treating cardiac infarction using hmgb1 fragment |
CN104955470B (zh) | 2012-10-25 | 2017-06-16 | 吉诺米克斯股份有限公司 | 利用了hmgb1片段的针对脊髄损伤的新型治疗方法 |
PL2956165T3 (pl) | 2013-02-14 | 2020-04-30 | The Board Of Trustees Of The University Of Arkansas | Kompozycje i sposoby wzmacniania odpowiedzi immunologicznych na Eimeria lub ograniczania infekcji Eimeria |
EA033538B1 (ru) | 2013-03-15 | 2019-10-31 | Univ Arkansas | Композиции и способы усиления иммунного ответа на кишечные патогены |
US11274144B2 (en) | 2013-06-13 | 2022-03-15 | Research Institute At Nationwide Children's Hospital | Compositions and methods for the removal of biofilms |
US9745366B2 (en) | 2013-09-23 | 2017-08-29 | University Of Southern California | Compositions and methods for the prevention of microbial infections |
US11248040B2 (en) | 2013-09-26 | 2022-02-15 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
US10233234B2 (en) | 2014-01-13 | 2019-03-19 | Trellis Bioscience, Llc | Binding moieties for biofilm remediation |
JP2018528763A (ja) | 2015-07-31 | 2018-10-04 | リサーチ インスティチュート アット ネイションワイド チルドレンズ ホスピタル | バイオフィルムの除去のためのペプチドおよび抗体 |
GB201600075D0 (en) | 2016-01-03 | 2016-02-17 | Glaxosmithkline Biolog Sa | Immunogenci composition |
US10682398B2 (en) | 2016-05-03 | 2020-06-16 | The Texas A&M University System | Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same |
WO2018047917A1 (ja) * | 2016-09-09 | 2018-03-15 | 国立大学法人 東京大学 | Hmgタンパク質と抗cd4抗体又は免疫チェックポイント制御剤との組み合わせによる相乗的抗腫瘍効果 |
CA3051825A1 (en) | 2017-01-27 | 2018-08-02 | StemRIM Inc. | Therapeutic agent for cardiomyopathy, old myocardial infarction and chronic heart failure |
AU2018236271B2 (en) | 2017-03-15 | 2023-12-21 | Research Institute At Nationwide Children's Hospital | Composition and methods for disruption of bacterial biofilms without accompanying inflammation |
US11298403B2 (en) | 2017-12-01 | 2022-04-12 | StemRIM Inc. | Therapeutic agent for inflammatory bowel disease |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5214131A (en) * | 1988-05-06 | 1993-05-25 | Sumitomo Pharmaceuticals Company, Limited | Polyethylene glycol derivatives, modified peptides and production thereof |
US5091176A (en) * | 1988-11-02 | 1992-02-25 | W. R. Grace & Co.-Conn. | Polymer-modified peptide drugs having enhanced biological and pharmacological activities |
JPH04218000A (ja) * | 1990-02-13 | 1992-08-07 | Kirin Amgen Inc | 修飾ポリペプチド |
US5811512A (en) * | 1991-08-22 | 1998-09-22 | The Trustees Of The University Of Pennsylvania | Non-peptide peptidomimetics and related cyclic hexapeptides |
US5580853A (en) * | 1994-03-22 | 1996-12-03 | New England Deaconess Hospital | Modified polypeptides with increased biological activity |
US5891418A (en) * | 1995-06-07 | 1999-04-06 | Rhomed Incorporated | Peptide-metal ion pharmaceutical constructs and applications |
FR2739292B1 (fr) * | 1995-09-28 | 1997-10-31 | Rhone Poulenc Rorer Sa | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
IT1299583B1 (it) * | 1998-05-19 | 2000-03-16 | Vander Way Limited | Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica |
US6100090A (en) * | 1999-06-25 | 2000-08-08 | Isis Pharmaceuticals Inc. | Antisense inhibition of PI3K p85 expression |
US6303321B1 (en) * | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
-
2001
- 2001-09-25 IT IT2001MI001986A patent/ITMI20011986A1/it unknown
-
2002
- 2002-09-25 AU AU2002341266A patent/AU2002341266B2/en not_active Ceased
- 2002-09-25 DE DE60233147T patent/DE60233147D1/de not_active Expired - Lifetime
- 2002-09-25 AT AT02775057T patent/ATE437652T1/de not_active IP Right Cessation
- 2002-09-25 WO PCT/IB2002/004080 patent/WO2003026691A2/en active Application Filing
- 2002-09-25 CA CA002461091A patent/CA2461091A1/en not_active Abandoned
- 2002-09-25 US US10/489,878 patent/US20040242481A1/en not_active Abandoned
- 2002-09-25 EP EP02775057A patent/EP1432441B1/de not_active Expired - Lifetime
- 2002-09-25 JP JP2003530326A patent/JP2005508913A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
WO2003026691A3 (en) | 2003-05-30 |
US20040242481A1 (en) | 2004-12-02 |
EP1432441A2 (de) | 2004-06-30 |
WO2003026691A2 (en) | 2003-04-03 |
EP1432441B1 (de) | 2009-07-29 |
ITMI20011986A0 (it) | 2001-09-25 |
CA2461091A1 (en) | 2003-04-03 |
ITMI20011986A1 (it) | 2003-03-25 |
AU2002341266B2 (en) | 2007-11-15 |
DE60233147D1 (de) | 2009-09-10 |
JP2005508913A (ja) | 2005-04-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |