ATE425754T1 - Bezdioxan-piperazin-derivate mit einer kombination aus affinitat fur dopamin-d2- rezeptoren und serotonin-wiederaufnahme-stellen - Google Patents
Bezdioxan-piperazin-derivate mit einer kombination aus affinitat fur dopamin-d2- rezeptoren und serotonin-wiederaufnahme-stellenInfo
- Publication number
- ATE425754T1 ATE425754T1 AT05817508T AT05817508T ATE425754T1 AT E425754 T1 ATE425754 T1 AT E425754T1 AT 05817508 T AT05817508 T AT 05817508T AT 05817508 T AT05817508 T AT 05817508T AT E425754 T1 ATE425754 T1 AT E425754T1
- Authority
- AT
- Austria
- Prior art keywords
- bezdioxan
- dopamine
- receptors
- affinity
- combination
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63344704P | 2004-12-07 | 2004-12-07 | |
EP04106361 | 2004-12-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE425754T1 true ATE425754T1 (de) | 2009-04-15 |
Family
ID=34930008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05817508T ATE425754T1 (de) | 2004-12-07 | 2005-12-06 | Bezdioxan-piperazin-derivate mit einer kombination aus affinitat fur dopamin-d2- rezeptoren und serotonin-wiederaufnahme-stellen |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1824486B1 (de) |
JP (1) | JP2008523028A (de) |
KR (1) | KR20070087644A (de) |
CN (1) | CN101072563A (de) |
AR (1) | AR052332A1 (de) |
AT (1) | ATE425754T1 (de) |
AU (1) | AU2005313388A1 (de) |
BR (1) | BRPI0518372A2 (de) |
CA (1) | CA2587940A1 (de) |
MX (1) | MX2007006758A (de) |
RU (1) | RU2007125691A (de) |
SA (1) | SA05260390B1 (de) |
TW (1) | TW200631952A (de) |
WO (1) | WO2006061374A1 (de) |
ZA (1) | ZA200704156B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8063062B2 (en) | 2006-12-20 | 2011-11-22 | Solvay Pharmaceuticals B.V. | Compounds with a combination of cannabinoid-CB1 antagonism and acetylcholinesterase inhibition |
US8138174B2 (en) | 2007-01-10 | 2012-03-20 | Solvay Pharmaceuticals B.V. | Compounds with a combination of cannabinoid CB1 antagonism and serotonin reuptake inhibition |
EP2111394A1 (de) * | 2007-01-10 | 2009-10-28 | Solvay Pharmaceuticals B.V. | Verbindungen mit einer kombination aus cannabinoid-cb1-antagonismus und serotonin-wiederaufnahmehemmung |
KR101387970B1 (ko) | 2011-04-20 | 2014-04-25 | 인제대학교 산학협력단 | 암 예방 및 치료용 조성물 및 건강기능식품 |
US9598401B2 (en) | 2013-07-29 | 2017-03-21 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
CN110041318B (zh) * | 2018-01-17 | 2022-07-29 | 中国科学院上海药物研究所 | 一类多巴胺d5受体激动剂及其制备和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
WO1999005140A1 (en) * | 1997-07-25 | 1999-02-04 | H. Lundbeck A/S | Indole and 2,3-dihydroindole derivatives, their preparation and use |
SK287018B6 (sk) * | 1999-08-23 | 2009-09-07 | Solvay Pharmaceuticals B. V. | Deriváty fenylpiperazínov, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitie |
DE10259244A1 (de) * | 2002-12-17 | 2004-07-01 | Merck Patent Gmbh | N-(Indolethyl-)cycloamin-Verbindungen |
-
2005
- 2005-12-06 SA SA05260390A patent/SA05260390B1/ar unknown
- 2005-12-06 EP EP05817508A patent/EP1824486B1/de active Active
- 2005-12-06 CA CA002587940A patent/CA2587940A1/en not_active Abandoned
- 2005-12-06 BR BRPI0518372-3A patent/BRPI0518372A2/pt not_active IP Right Cessation
- 2005-12-06 AT AT05817508T patent/ATE425754T1/de not_active IP Right Cessation
- 2005-12-06 MX MX2007006758A patent/MX2007006758A/es active IP Right Grant
- 2005-12-06 TW TW094142943A patent/TW200631952A/zh unknown
- 2005-12-06 AR ARP050105088A patent/AR052332A1/es not_active Application Discontinuation
- 2005-12-06 WO PCT/EP2005/056503 patent/WO2006061374A1/en active Application Filing
- 2005-12-06 CN CNA200580042069XA patent/CN101072563A/zh active Pending
- 2005-12-06 RU RU2007125691/04A patent/RU2007125691A/ru not_active Application Discontinuation
- 2005-12-06 KR KR1020077015622A patent/KR20070087644A/ko not_active Application Discontinuation
- 2005-12-06 AU AU2005313388A patent/AU2005313388A1/en not_active Abandoned
- 2005-12-06 JP JP2007544894A patent/JP2008523028A/ja not_active Withdrawn
-
2007
- 2007-05-22 ZA ZA200704156A patent/ZA200704156B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2008523028A (ja) | 2008-07-03 |
SA05260390B1 (ar) | 2009-04-01 |
RU2007125691A (ru) | 2009-01-20 |
MX2007006758A (es) | 2007-11-09 |
CA2587940A1 (en) | 2006-06-15 |
AR052332A1 (es) | 2007-03-14 |
EP1824486B1 (de) | 2009-03-18 |
ZA200704156B (en) | 2008-05-28 |
BRPI0518372A2 (pt) | 2008-11-18 |
KR20070087644A (ko) | 2007-08-28 |
EP1824486A1 (de) | 2007-08-29 |
AU2005313388A1 (en) | 2006-06-15 |
CN101072563A (zh) | 2007-11-14 |
TW200631952A (en) | 2006-09-16 |
WO2006061374A1 (en) | 2006-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |