MA28902B1 - Agonistes des recepteurs beta2 adrenergiques diaminiques - Google Patents
Agonistes des recepteurs beta2 adrenergiques diaminiquesInfo
- Publication number
- MA28902B1 MA28902B1 MA29566A MA29566A MA28902B1 MA 28902 B1 MA28902 B1 MA 28902B1 MA 29566 A MA29566 A MA 29566A MA 29566 A MA29566 A MA 29566A MA 28902 B1 MA28902 B1 MA 28902B1
- Authority
- MA
- Morocco
- Prior art keywords
- diaminic
- agonists
- adrenergic receptors
- beta2 adrenergic
- beta2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57656004P | 2004-06-03 | 2004-06-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA28902B1 true MA28902B1 (fr) | 2007-10-01 |
Family
ID=35115813
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA29566A MA28902B1 (fr) | 2004-06-03 | 2006-12-28 | Agonistes des recepteurs beta2 adrenergiques diaminiques |
Country Status (14)
Country | Link |
---|---|
US (2) | US7402673B2 (fr) |
EP (1) | EP1751086A2 (fr) |
JP (1) | JP2008501705A (fr) |
CN (1) | CN1984876A (fr) |
AU (1) | AU2005252226A1 (fr) |
BR (1) | BRPI0511695A (fr) |
CA (1) | CA2569395A1 (fr) |
IL (1) | IL179631A0 (fr) |
MA (1) | MA28902B1 (fr) |
MX (1) | MXPA06013916A (fr) |
NO (1) | NO20066016L (fr) |
RU (1) | RU2006146042A (fr) |
WO (1) | WO2005121065A2 (fr) |
ZA (1) | ZA200610835B (fr) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI249515B (en) * | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
TW200526547A (en) * | 2003-09-22 | 2005-08-16 | Theravance Inc | Amino-substituted ethylamino β2 adrenergic receptor agonists |
TW200531692A (en) * | 2004-01-12 | 2005-10-01 | Theravance Inc | Aryl aniline derivatives as β2 adrenergic receptor agonists |
US7402673B2 (en) * | 2004-06-03 | 2008-07-22 | Theravance, Inc. | Diamine β2 adrenergic receptor agonists |
WO2006014704A1 (fr) * | 2004-07-21 | 2006-02-09 | Theravance, Inc. | AGONISTES DES RÉCEPTEURS β2-ADRÉNERGIQUES DÉRIVÉS D'ÉTHERS DE DIARYLE |
US7566785B2 (en) * | 2004-09-10 | 2009-07-28 | Theravance, Inc. | Amidine substituted aryl aniline compounds |
ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
KR20080036632A (ko) | 2005-08-08 | 2008-04-28 | 아젠터 디스커버리 리미티드 | 바이시클로[2.2.1]헵트-7-일아민 유도체 및 이들의 용도 |
TW200738658A (en) | 2005-08-09 | 2007-10-16 | Astrazeneca Ab | Novel compounds |
US8653145B2 (en) * | 2005-09-22 | 2014-02-18 | Eaton Scientific Systems, Ltd. | Method for alleviating climacteric symptoms |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
TW200745067A (en) | 2006-03-14 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
ES2296516B1 (es) * | 2006-04-27 | 2009-04-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
WO2008041914A1 (fr) * | 2006-10-06 | 2008-04-10 | Astrazeneca Ab | DÉRIVÉS DE LA 5-(2-AMINO-1-HYDROXYÉTHYL)-8-HYDROXY-2-OXOQUINOLÉINE ET AUTRES COMPOSÉS EN TANT QU'AGONISTES β2-ADRÉNERGIQUES |
ES2302447B1 (es) * | 2006-10-20 | 2009-06-12 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
TW200833670A (en) | 2006-12-20 | 2008-08-16 | Astrazeneca Ab | Novel compounds 569 |
GB0702458D0 (en) | 2007-02-08 | 2007-03-21 | Astrazeneca Ab | Salts 668 |
ES2306595B1 (es) | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
ES2320961B1 (es) * | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
KR20100113557A (ko) | 2008-01-11 | 2010-10-21 | 노파르티스 아게 | 키나제 억제제로서의 피리미딘 |
EP2096105A1 (fr) * | 2008-02-28 | 2009-09-02 | Laboratorios Almirall, S.A. | Dérivés de 4-(2-amino-1-hydroxyethyl)phénol en tant qu'antagonistes du récepteur adrénergique b2 |
EP2303873A4 (fr) | 2008-06-18 | 2012-01-04 | Astrazeneca Ab | Dérivés de benzoxazinone agissant comme agoniste des récepteurs bêta2-adrénergiques pour le traitement de troubles respiratoires |
US8236786B2 (en) * | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
UY32297A (es) | 2008-12-22 | 2010-05-31 | Almirall Sa | Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico |
PT2379507E (pt) | 2008-12-30 | 2014-01-21 | Pulmagen Therapeutics Inflammation Ltd | Compostos de sulfonamida para o tratamento de desordens respiratórias |
EP2228368A1 (fr) | 2009-03-12 | 2010-09-15 | Almirall, S.A. | Procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-ph2nyl2thoxy)hexyl]amino}-1-hydroxy2thyl)-8-hydroxyquinolin-2(1h)-one |
WO2010150014A1 (fr) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | Glitazones 5r-5–deutérés pour le traitement de maladies respiratoires |
GB0918924D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Azaindole derivatives |
GB0918923D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminothiazole derivatives |
GB0918922D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminopyridine derivatives |
WO2011061527A1 (fr) | 2009-11-17 | 2011-05-26 | Astrazeneca Ab | Combinaisons qui comprennent un modulateur du récepteur glucocorticoïde, destinées au traitement de maladies respiratoires |
WO2011098746A1 (fr) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Sels d'addition acide cristallins de l'énantiomère (5r) de la pioglitazone |
GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
WO2012034095A1 (fr) | 2010-09-09 | 2012-03-15 | Irm Llc | Composés et compositions comme inhibiteurs de trk |
GB201016912D0 (en) | 2010-10-07 | 2010-11-24 | Astrazeneca Ab | Novel combination |
PE20140378A1 (es) | 2011-02-25 | 2014-03-28 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
EP2578570A1 (fr) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Nouveau procédé de fabrication de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy)hexyl]amino}-1-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one via de nouveaux intermédiaires de synthèse |
EP2641900A1 (fr) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Nouvelles formes polymorphes de héminapadisylate de 5-(2-{[6-(2,2-difluoro-2-phényléthoxy) hexyl]amino}-1-(R)-hydroxyéthyl)-8-hydroxyquinolin-2(1h)-one en tant qu'agoniste du récepteur adrénergique ß2 |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1158082B (de) | 1960-12-17 | 1963-11-28 | Gruenenthal Chemie | Verfahren zur Herstellung von Alkylendiaminderivaten und deren Salzen |
DE1250450B (de) | 1962-03-31 | 1967-09-21 | Deutsche Gold- und Silber-Scheideanstalt vormals Roessler, Frankfurt/M | Verfahren zur Herstellung von Aminoalkoholen sowie deren Säureadditionssalzen und quartären Ammoniumverbindungen |
US3775477A (en) * | 1971-03-10 | 1973-11-27 | Sterling Drug Inc | N,n'-bis(2-aryl-2-(hydroxy or oxo)-ethyl)-bridged-bis-carboxamides |
AT310146B (de) | 1971-04-26 | 1973-09-25 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von neuen N,N'-Bis-(β-hydroxyaryläthyl)-diaminoalkanen und deren Säureadditionssalzen |
BE794414A (fr) * | 1972-01-25 | 1973-07-23 | Sandoz Sa | Nouveaux amino-alcools, leur preparation et leur application comme medicament |
GB1460593A (en) | 1973-06-22 | 1977-01-06 | Ici Ltd | Ethanolamine derivatives |
JPS5913510B2 (ja) | 1975-12-26 | 1984-03-30 | オオツカセイヤク カブシキガイシヤ | カルボスチリルユウドウタイノセイゾウホウ |
JPS5283619A (en) | 1976-01-01 | 1977-07-12 | Yamanouchi Pharmaceut Co Ltd | Alpha-substituted aminomethyl benzyl alcohol derivative |
JPS609713B2 (ja) | 1976-10-08 | 1985-03-12 | 大塚製薬株式会社 | カルボスチリル誘導体 |
ZW6584A1 (en) | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
GB8334494D0 (en) | 1983-12-24 | 1984-02-01 | Tanabe Seiyaku Co | Carbostyril derivatives |
US4853381A (en) | 1984-04-17 | 1989-08-01 | Glaxo Group Limited | Ethanolamine compounds |
GB8426200D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
GB8507942D0 (en) | 1985-03-27 | 1985-05-01 | Beecham Group Plc | Compounds |
EP0233686A3 (fr) | 1986-01-11 | 1989-05-03 | Beecham Group Plc | Bis phényléthanolamines et bis phénoxypropanolamines ayant une activité bêta-agoniste |
US5223614A (en) | 1987-12-19 | 1993-06-29 | Boehringer Ingelheim Gmbh | New quaternary ammonium compounds, their preparation and use |
US4894219A (en) | 1988-03-29 | 1990-01-16 | University Of Florida | Beta-agonist carbostyril derivatives, assay method and pharmacological composition |
US5434304A (en) * | 1990-09-26 | 1995-07-18 | Aktiebolaget Astra | Process for preparing formoterol and related compounds |
GB9405019D0 (en) * | 1994-03-15 | 1994-04-27 | Smithkline Beecham Plc | Novel compounds |
US6040344A (en) * | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
GB9713819D0 (en) * | 1997-06-30 | 1997-09-03 | Glaxo Group Ltd | Method of reducing the systemic effects of compounds |
US6362371B1 (en) | 1998-06-08 | 2002-03-26 | Advanced Medicine, Inc. | β2- adrenergic receptor agonists |
US6683115B2 (en) * | 1999-06-02 | 2004-01-27 | Theravance, Inc. | β2-adrenergic receptor agonists |
US6593497B1 (en) | 1999-06-02 | 2003-07-15 | Theravance, Inc. | β2-adrenergic receptor agonists |
UA73965C2 (en) * | 1999-12-08 | 2005-10-17 | Theravance Inc | b2 ADRENERGIC RECEPTOR ANTAGONISTS |
OA11558A (en) | 1999-12-08 | 2004-06-03 | Advanced Medicine Inc | Beta 2-adrenergic receptor agonists. |
MXPA02010179A (es) | 2000-04-27 | 2003-04-25 | Boehringer Ingelheim Pharma | Nuevos betamimeticos de larga accion, procedimiento para su preparacion y su empleo como medicamentos. |
US6759398B2 (en) | 2000-08-05 | 2004-07-06 | Smithkline Beecham Corporation | Anti-inflammatory androstane derivative |
GB0103630D0 (en) * | 2001-02-14 | 2001-03-28 | Glaxo Group Ltd | Chemical compounds |
US7144908B2 (en) | 2001-03-08 | 2006-12-05 | Glaxo Group Limited | Agonists of beta-adrenoceptors |
EP1370521B1 (fr) | 2001-03-22 | 2007-12-19 | Glaxo Group Limited | Derives formanilides utilises en tant qu'agonistes de l'adrenorecepteur beta2 |
MXPA04002405A (es) | 2001-09-14 | 2004-05-31 | Glaxo Group Limetd | Derivados de fenetanolamina para tratamiento de enfermedades respiratorias. |
US20030229058A1 (en) | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
TWI249515B (en) | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
WO2003042160A1 (fr) * | 2001-11-13 | 2003-05-22 | Theravance, Inc. | Agonistes de recepteur d'aryl aniline beta-2 adrenergique |
GB0204719D0 (en) | 2002-02-28 | 2002-04-17 | Glaxo Group Ltd | Medicinal compounds |
EP1507754A1 (fr) * | 2002-05-28 | 2005-02-23 | Theravance, Inc. | Agonistes du recepteur adrenergique beta 2 alcoxy aryle |
GB0217225D0 (en) | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicinal compounds |
PE20050130A1 (es) | 2002-08-09 | 2005-03-29 | Novartis Ag | Compuestos organicos |
GB0225030D0 (en) | 2002-10-28 | 2002-12-04 | Glaxo Group Ltd | Medicinal compounds |
GB0225540D0 (en) | 2002-11-01 | 2002-12-11 | Glaxo Group Ltd | Medicinal compounds |
TW200526547A (en) | 2003-09-22 | 2005-08-16 | Theravance Inc | Amino-substituted ethylamino β2 adrenergic receptor agonists |
TW200531692A (en) * | 2004-01-12 | 2005-10-01 | Theravance Inc | Aryl aniline derivatives as β2 adrenergic receptor agonists |
US7402673B2 (en) * | 2004-06-03 | 2008-07-22 | Theravance, Inc. | Diamine β2 adrenergic receptor agonists |
-
2005
- 2005-06-02 US US11/143,075 patent/US7402673B2/en active Active
- 2005-06-02 WO PCT/US2005/019549 patent/WO2005121065A2/fr active Application Filing
- 2005-06-02 US US11/597,876 patent/US20080039495A1/en not_active Abandoned
- 2005-06-02 RU RU2006146042/04A patent/RU2006146042A/ru unknown
- 2005-06-02 CA CA002569395A patent/CA2569395A1/fr not_active Abandoned
- 2005-06-02 AU AU2005252226A patent/AU2005252226A1/en not_active Abandoned
- 2005-06-02 CN CNA2005800240610A patent/CN1984876A/zh active Pending
- 2005-06-02 MX MXPA06013916A patent/MXPA06013916A/es not_active Application Discontinuation
- 2005-06-02 BR BRPI0511695-3A patent/BRPI0511695A/pt not_active Application Discontinuation
- 2005-06-02 JP JP2007515611A patent/JP2008501705A/ja not_active Withdrawn
- 2005-06-02 EP EP05757438A patent/EP1751086A2/fr not_active Withdrawn
-
2006
- 2006-11-27 IL IL179631A patent/IL179631A0/en unknown
- 2006-12-21 ZA ZA200610835A patent/ZA200610835B/xx unknown
- 2006-12-27 NO NO20066016A patent/NO20066016L/no not_active Application Discontinuation
- 2006-12-28 MA MA29566A patent/MA28902B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200610835B (en) | 2007-11-28 |
WO2005121065A2 (fr) | 2005-12-22 |
RU2006146042A (ru) | 2008-07-20 |
MXPA06013916A (es) | 2007-03-07 |
US7402673B2 (en) | 2008-07-22 |
NO20066016L (no) | 2007-02-27 |
WO2005121065A3 (fr) | 2006-02-09 |
US20050272769A1 (en) | 2005-12-08 |
BRPI0511695A (pt) | 2008-01-08 |
CA2569395A1 (fr) | 2005-12-22 |
EP1751086A2 (fr) | 2007-02-14 |
IL179631A0 (en) | 2007-05-15 |
JP2008501705A (ja) | 2008-01-24 |
CN1984876A (zh) | 2007-06-20 |
AU2005252226A1 (en) | 2005-12-22 |
US20080039495A1 (en) | 2008-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MA28902B1 (fr) | Agonistes des recepteurs beta2 adrenergiques diaminiques | |
DE602005027307D1 (de) | Arylanilinderivate als agonisten des beta2-adrenergen rezeptors | |
DK1735304T3 (da) | Quinolinoncarboxamidforbindelser som 5-HT4-receptoragonister | |
DE602006007563D1 (de) | Agonisten | |
ATE549350T1 (de) | Neuropeptid-2-rezeptor-agonisten | |
BRPI0719626A2 (pt) | '' composto '' | |
ATE443753T1 (de) | Nuancierungsmittel | |
DK2027096T3 (da) | Substituerede arylimidazoloner og -triazoloner som inhibitorer for vasopressinreceptorerne | |
AP2009004791A0 (en) | Sulfonamide derivatives as adrenergic agonists andmuscarinic antagonists | |
DK1899324T3 (da) | Benzimidazolcarboxamid-forbindelser som 5-HT4-receptoragonister | |
MA28361A1 (fr) | Modulateurs des recepteurs d'androgenes | |
DK1749001T3 (da) | 3-piperidinylisochroman-5-ol som dopaminagonister | |
NO20052102D0 (no) | Modem | |
DK2091938T3 (da) | Piperidinylaminopyridaziner og anvendelse deraf som hurtigt opløsende antagonister af dopamin-2-receptorer | |
ITMI20042239A1 (it) | Additivi per fluoropolieterei | |
ITTO20060410A1 (it) | "dispositivo anti-russamento" | |
FR2895710B1 (fr) | Monopode d'arrimage pour brancard | |
FR2921063B1 (fr) | Ligands des recepteurs cannabinoides | |
DE602007000875D1 (de) | Nadelhalter | |
AT7230U3 (de) | Wasserpfeife | |
AT500804B1 (de) | Abstandhalter | |
ITMI20060150U1 (it) | "fresa" | |
FI20065415A0 (fi) | Käyttöliittymä | |
FI7545U1 (fi) | Puomin päähän tarkoitettu riipukelaite | |
FI7152U1 (fi) | Pesualtaan kannatinlaite |