ATE425460T1 - Antikörper, immunoassay und verfahren zum nachweis von prostatakrebs - Google Patents
Antikörper, immunoassay und verfahren zum nachweis von prostatakrebsInfo
- Publication number
- ATE425460T1 ATE425460T1 AT01972118T AT01972118T ATE425460T1 AT E425460 T1 ATE425460 T1 AT E425460T1 AT 01972118 T AT01972118 T AT 01972118T AT 01972118 T AT01972118 T AT 01972118T AT E425460 T1 ATE425460 T1 AT E425460T1
- Authority
- AT
- Austria
- Prior art keywords
- pca
- patients
- psa
- antibody
- chain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI20002127A FI20002127A0 (fi) | 2000-09-27 | 2000-09-27 | Uusi vasta-aine, immunomääritys ja menetelmä eturauhassyövän havaitsemiseksi |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE425460T1 true ATE425460T1 (de) | 2009-03-15 |
Family
ID=8559172
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01972118T ATE425460T1 (de) | 2000-09-27 | 2001-09-26 | Antikörper, immunoassay und verfahren zum nachweis von prostatakrebs |
Country Status (9)
Country | Link |
---|---|
US (1) | US7872104B2 (de) |
EP (1) | EP1320756B1 (de) |
JP (1) | JP5254517B2 (de) |
AT (1) | ATE425460T1 (de) |
AU (1) | AU2001291911A1 (de) |
DE (1) | DE60137949D1 (de) |
ES (1) | ES2322432T3 (de) |
FI (1) | FI20002127A0 (de) |
WO (1) | WO2002027323A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103495439B (zh) | 2007-05-04 | 2015-09-16 | 欧普科诊断有限责任公司 | 流体连接器和微流体系统 |
ES2812260T3 (es) | 2009-02-02 | 2021-03-16 | Opko Diagnostics Llc | Estructuras para controlar la interacción de luz con dispositivos microfluídicos |
CA2853705C (en) * | 2011-10-25 | 2021-10-12 | Memorial Sloan-Kettering Cancer Center | Free psa antibodies as diagnostics, prognostics and therapeutics for prostate cancer |
EP2771037B1 (de) | 2011-10-28 | 2016-08-03 | Fredax AB | Therapeutische wirkstoffe und ihre verwendung |
BR112014021776B1 (pt) * | 2012-03-05 | 2022-08-09 | Opko Diagnostics, Llc | Sistema de ensaio e método para a determinação de uma probabilidade de um evento associado com o câncer da próstata |
JP6312141B2 (ja) * | 2012-03-30 | 2018-04-18 | 国立大学法人京都大学 | 前立腺がん検査用尿中バイオマーカー |
KR102442738B1 (ko) | 2013-11-19 | 2022-09-15 | 프레닥스 에이비 | 인간화된 안티 칼리크레인-2 항체 |
SG10201808585TA (en) * | 2014-03-28 | 2018-11-29 | Opko Diagnostics Llc | Compositions and methods related to diagnosis of prostate cancer |
ES2867798T3 (es) | 2015-03-27 | 2021-10-20 | Opko Diagnostics Llc | Estándares del antígeno prostático y usos de estos |
EP3922265A1 (de) * | 2015-10-05 | 2021-12-15 | Fredax AB | Humanisierte anti psa (5a10) antikörper |
CN109991405B (zh) * | 2017-12-29 | 2023-01-24 | 上海索昕生物科技有限公司 | 一种免疫检测试剂盒及其应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0635575A1 (de) * | 1993-07-22 | 1995-01-25 | Wallac Oy | Monoklonale Antikörper gegen Epitope in freiem uber nicht in Alpha-1-antichymotrypsin komplexiertem Prostata spezifisches Antigen |
US6143509A (en) * | 1996-02-06 | 2000-11-07 | Abbott Laboratories | Prostate specific antigen peptides and uses thereof |
JPH10150999A (ja) * | 1996-11-22 | 1998-06-09 | Eiken Chem Co Ltd | ヒト前立腺特異抗原−α1−アンチキモトリプシン複合体に対するモノクローナル抗体及びそれを用いたヒト前立腺特異抗原−α1−アンチキモトリプシン複合体の免疫学的検出法 |
US5858685A (en) * | 1997-03-21 | 1999-01-12 | The Board Of Trustees Of The Leland Stanford Junior University | Prostate specific antigen from benign prostatic hyperplasia and its use in diagnosis |
US7659073B2 (en) * | 1997-04-30 | 2010-02-09 | Hybritech Incorporated | Forms of prostate specific antigens and methods for their detection |
CA2286090C (en) * | 1997-04-30 | 2013-01-08 | Hybritech Incorporated | Forms of prostate specific antigen and methods for their detection |
US7211397B2 (en) * | 1999-04-30 | 2007-05-01 | Beckman Coulter, Inc. | Method of analyzing non-complexed forms of prostate specific antigen in a sample to improve prostate cancer detection |
US6482599B1 (en) * | 1999-04-30 | 2002-11-19 | Hybritech Incorporated | Forms of prostate specific antigen (PSA) specific for benign prostatic hyperplasia (BPH) and methods of using such |
US6423503B1 (en) * | 1999-04-30 | 2002-07-23 | Hybritech Incorporated | Forms of free prostate-specific antigen (PSA) and their association with prostate tissues from prostate peripheral zone and transition zone |
-
2000
- 2000-09-27 FI FI20002127A patent/FI20002127A0/fi unknown
-
2001
- 2001-09-26 WO PCT/FI2001/000834 patent/WO2002027323A1/en active Application Filing
- 2001-09-26 US US10/381,132 patent/US7872104B2/en not_active Expired - Lifetime
- 2001-09-26 EP EP01972118A patent/EP1320756B1/de not_active Expired - Lifetime
- 2001-09-26 AT AT01972118T patent/ATE425460T1/de not_active IP Right Cessation
- 2001-09-26 ES ES01972118T patent/ES2322432T3/es not_active Expired - Lifetime
- 2001-09-26 JP JP2002530851A patent/JP5254517B2/ja not_active Expired - Lifetime
- 2001-09-26 AU AU2001291911A patent/AU2001291911A1/en not_active Abandoned
- 2001-09-26 DE DE60137949T patent/DE60137949D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US7872104B2 (en) | 2011-01-18 |
WO2002027323A1 (en) | 2002-04-04 |
US20040101914A1 (en) | 2004-05-27 |
DE60137949D1 (de) | 2009-04-23 |
AU2001291911A1 (en) | 2002-04-08 |
EP1320756B1 (de) | 2009-03-11 |
EP1320756A1 (de) | 2003-06-25 |
JP5254517B2 (ja) | 2013-08-07 |
ES2322432T3 (es) | 2009-06-22 |
FI20002127A0 (fi) | 2000-09-27 |
JP2004509934A (ja) | 2004-04-02 |
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