ATE404676T1 - Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung - Google Patents

Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung

Info

Publication number
ATE404676T1
ATE404676T1 AT98918814T AT98918814T ATE404676T1 AT E404676 T1 ATE404676 T1 AT E404676T1 AT 98918814 T AT98918814 T AT 98918814T AT 98918814 T AT98918814 T AT 98918814T AT E404676 T1 ATE404676 T1 AT E404676T1
Authority
AT
Austria
Prior art keywords
ppsa
psa
prostate
determination
specific antigen
Prior art date
Application number
AT98918814T
Other languages
English (en)
Inventor
Mohammad Saedi
Stephen Mikolajczyk
Abhay Kumar
Lana Grauer
Robert Wolfert
Harry Rittenhouse
Original Assignee
Hybritech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc filed Critical Hybritech Inc
Application granted granted Critical
Publication of ATE404676T1 publication Critical patent/ATE404676T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98918814T 1997-04-30 1998-04-28 Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung ATE404676T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84640897A 1997-04-30 1997-04-30

Publications (1)

Publication Number Publication Date
ATE404676T1 true ATE404676T1 (de) 2008-08-15

Family

ID=25297849

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918814T ATE404676T1 (de) 1997-04-30 1998-04-28 Prostat-spezifisches-antigenformen und verfahren zu ihrer bestimmung

Country Status (8)

Country Link
EP (1) EP0981629B1 (de)
JP (1) JP5284554B2 (de)
AT (1) ATE404676T1 (de)
AU (1) AU739546B2 (de)
CA (1) CA2286090C (de)
DE (1) DE69839876D1 (de)
ES (1) ES2312186T3 (de)
WO (1) WO1998049323A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7659073B2 (en) 1997-04-30 2010-02-09 Hybritech Incorporated Forms of prostate specific antigens and methods for their detection
US7288636B2 (en) 1997-04-30 2007-10-30 Hybritech Incorporated Forms of prostate specific antigens and methods for their detection
US6300088B1 (en) 1997-11-24 2001-10-09 Duke University Method of detecting prostate specific antigen
JP4495349B2 (ja) 1999-01-28 2010-07-07 ジェン−プローブ・インコーポレーテッド 癌の遺伝マーカーを生物学的サンプルにおいて検出するための核酸配列
US20030219840A1 (en) * 2002-05-24 2003-11-27 Mikolajczyk Stephen D. Method of analyzing proenzyme forms of prostate specific antigen in serum to improve prostate cancer detection
US6423503B1 (en) * 1999-04-30 2002-07-23 Hybritech Incorporated Forms of free prostate-specific antigen (PSA) and their association with prostate tissues from prostate peripheral zone and transition zone
ES2277846T3 (es) * 1999-07-29 2007-08-01 Medarex, Inc. Anticuerpos monoclonales humanos para antigeno prostatico especifico.
FR2807438B1 (fr) * 2000-04-10 2004-09-17 Bio Merieux Nouveaux anticorps reconnaissant specifiquement le psa libre inactif, et leurs applications
ATE335765T1 (de) * 2000-05-24 2006-09-15 Hoffmann La Roche Antikörper gegen spezielle formen des propsa und deren verwendung in immunoassays
FI20002127A0 (fi) * 2000-09-27 2000-09-27 Artic Partners Oy Ab Uusi vasta-aine, immunomääritys ja menetelmä eturauhassyövän havaitsemiseksi
CN113237162B (zh) * 2021-05-28 2022-12-27 西安建筑科技大学 一种冷冻水循环系统控制优化方法、系统及设备

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08502889A (ja) * 1992-10-29 1996-04-02 トーマス・ジェファーソン・ユニバーシティ 前立腺癌の微小転移を検出する方法
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
EP0725139A3 (de) * 1995-02-03 1997-11-26 Bayer Corporation Rekombinantes prostat-spezifisches Antigen und seiner Verwendung als Immunoassay-Kalibrator
CA2218754A1 (en) * 1996-11-15 1998-05-15 Eli Lilly And Company Recombinant psa expression vectors and assays using the same

Also Published As

Publication number Publication date
EP0981629A1 (de) 2000-03-01
AU739546B2 (en) 2001-10-18
EP0981629B1 (de) 2008-08-13
WO1998049323A1 (en) 1998-11-05
JP2002501384A (ja) 2002-01-15
CA2286090C (en) 2013-01-08
AU7166898A (en) 1998-11-24
ES2312186T3 (es) 2009-02-16
JP5284554B2 (ja) 2013-09-11
DE69839876D1 (de) 2008-09-25
CA2286090A1 (en) 1998-11-05

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Legal Events

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