ATE424396T1 - Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamente - Google Patents
Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamenteInfo
- Publication number
- ATE424396T1 ATE424396T1 AT03760060T AT03760060T ATE424396T1 AT E424396 T1 ATE424396 T1 AT E424396T1 AT 03760060 T AT03760060 T AT 03760060T AT 03760060 T AT03760060 T AT 03760060T AT E424396 T1 ATE424396 T1 AT E424396T1
- Authority
- AT
- Austria
- Prior art keywords
- heteroarylmethylamino
- medications
- halogen
- production process
- methyl piperidine
- Prior art date
Links
- -1 METHYL PIPERIDINE-1-YL-METHANONE DERIVATIVES Chemical class 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- VUWZPRWSIVNGKG-UHFFFAOYSA-N fluoromethane Chemical compound F[CH2] VUWZPRWSIVNGKG-UHFFFAOYSA-N 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0207470A FR2840900B1 (fr) | 2002-06-18 | 2002-06-18 | Nouveaux derives d'aryl[4-halogeno-4- [(heteroaryl-methylamino)-methyl]-piperidin-1-yl]-methanone, leur procede de preparation et leur utilisation a titre de medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424396T1 true ATE424396T1 (de) | 2009-03-15 |
Family
ID=29595331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03760060T ATE424396T1 (de) | 2002-06-18 | 2003-06-18 | Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamente |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7547700B2 (https=) |
| EP (1) | EP1539738B1 (https=) |
| JP (1) | JP4699027B2 (https=) |
| CN (1) | CN1308325C (https=) |
| AT (1) | ATE424396T1 (https=) |
| AU (1) | AU2003258816B2 (https=) |
| BR (1) | BRPI0311976B8 (https=) |
| CA (1) | CA2489723C (https=) |
| DE (1) | DE60326468D1 (https=) |
| ES (1) | ES2321927T3 (https=) |
| FR (1) | FR2840900B1 (https=) |
| MX (1) | MXPA05000024A (https=) |
| WO (1) | WO2003106449A1 (https=) |
| ZA (1) | ZA200500467B (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2852244B1 (fr) * | 2003-03-13 | 2007-09-07 | Pf Medicament | Utilisation de derives de pyridin-2-yl-methylamine pour la preparation d'un medicament destine au traitement des symptomes de la douleur chronique d'origine neuropathique ou psychogene |
| FR2891274B1 (fr) * | 2005-09-27 | 2007-11-23 | Pierre Fabre Medicament Sa | Procede de preparation du (3-chloro-4-fluoro-phenyl)-(4- fluoro-4-{[(5-methyl-pyrimidin-2-ylmethyl)-amino]-methyl}- piperidin-1-yl)-methanone et nouveaux derives pyrimidiniques intermediaires. |
| US8389534B2 (en) * | 2008-05-19 | 2013-03-05 | The University Of Tennessee Research Foundation | Pyrimidine non-classical cannabinoid compounds and related methods of use |
| US8541431B2 (en) * | 2008-05-19 | 2013-09-24 | The University Of Tennessee Research Foundation | Pyrimidine non-classical cannabinoid compounds and related methods of use |
| FR2946344B1 (fr) | 2009-06-05 | 2012-05-25 | Pf Medicament | Nouveaux derives d'aryl-{4-halogeno-4-[aminomethyl]-piperidin-1-yl} methanone, leur procede de preparation et leur utilisation a titre de medicaments |
| EP2338873A1 (en) | 2009-12-22 | 2011-06-29 | Gmeiner, Peter | New aminotetraline derivatives |
| US10626105B2 (en) * | 2016-09-22 | 2020-04-21 | Auspex Pharmaceuticals, Inc. | Deuterium-substituted pyridin- and pyrimidin-2-yl-methylamine compounds |
| EP3664787B1 (en) | 2017-07-20 | 2022-07-20 | Neurolixis | Use of selective serotonin 5-ht1a receptor agonists for treating side-effects of vmat inhibitors |
| WO2023144166A1 (en) | 2022-01-26 | 2023-08-03 | Neurolixis | Use of serotonin 5-ht1a receptor agonists to treat diseases associated with sudden unexpected death in epilepsy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN169588B (https=) * | 1986-10-07 | 1991-11-16 | Pfizer Hospital Prod | |
| FR2755967B1 (fr) * | 1996-11-21 | 1999-01-29 | Pf Medicament | Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments |
| FR2784378B1 (fr) * | 1998-10-09 | 2000-12-29 | Pf Medicament | Nouveaux derives d'aryl-(4-fluoro-4-[(2-pyridin-2-yl- ethylamino)-methyl]-piperidin-1-yl)-methanone, leur procede de preparation et leur utilisation a titre de medicaments |
| FR2820743B1 (fr) * | 2001-02-09 | 2005-02-25 | Pf Medicament | Procede et intermediaires de synthese pour la preparation de derives de pyridin-2-yl-methylamine |
-
2002
- 2002-06-18 FR FR0207470A patent/FR2840900B1/fr not_active Expired - Lifetime
-
2003
- 2003-06-18 US US10/518,394 patent/US7547700B2/en not_active Expired - Lifetime
- 2003-06-18 ES ES03760060T patent/ES2321927T3/es not_active Expired - Lifetime
- 2003-06-18 CN CNB038186047A patent/CN1308325C/zh not_active Expired - Lifetime
- 2003-06-18 BR BRPI0311976A patent/BRPI0311976B8/pt not_active IP Right Cessation
- 2003-06-18 MX MXPA05000024A patent/MXPA05000024A/es active IP Right Grant
- 2003-06-18 AT AT03760060T patent/ATE424396T1/de not_active IP Right Cessation
- 2003-06-18 JP JP2004513281A patent/JP4699027B2/ja not_active Expired - Lifetime
- 2003-06-18 CA CA2489723A patent/CA2489723C/fr not_active Expired - Lifetime
- 2003-06-18 AU AU2003258816A patent/AU2003258816B2/en not_active Expired
- 2003-06-18 EP EP03760060A patent/EP1539738B1/fr not_active Expired - Lifetime
- 2003-06-18 WO PCT/FR2003/001873 patent/WO2003106449A1/fr not_active Ceased
- 2003-06-18 DE DE60326468T patent/DE60326468D1/de not_active Expired - Lifetime
-
2005
- 2005-01-18 ZA ZA2005/00467A patent/ZA200500467B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2489723A1 (fr) | 2003-12-24 |
| JP2005534668A (ja) | 2005-11-17 |
| EP1539738A1 (fr) | 2005-06-15 |
| WO2003106449A8 (fr) | 2005-02-17 |
| HK1075452A1 (en) | 2005-12-16 |
| US7547700B2 (en) | 2009-06-16 |
| BRPI0311976B8 (pt) | 2021-05-25 |
| CN1675194A (zh) | 2005-09-28 |
| ZA200500467B (en) | 2005-12-28 |
| FR2840900B1 (fr) | 2005-02-25 |
| JP4699027B2 (ja) | 2011-06-08 |
| AU2003258816B2 (en) | 2008-08-21 |
| US20060100244A1 (en) | 2006-05-11 |
| MXPA05000024A (es) | 2005-04-08 |
| WO2003106449A1 (fr) | 2003-12-24 |
| BRPI0311976B1 (pt) | 2015-08-18 |
| ES2321927T3 (es) | 2009-06-15 |
| AU2003258816A1 (en) | 2003-12-31 |
| FR2840900A1 (fr) | 2003-12-19 |
| DE60326468D1 (de) | 2009-04-16 |
| CA2489723C (fr) | 2011-08-02 |
| CN1308325C (zh) | 2007-04-04 |
| EP1539738B1 (fr) | 2009-03-04 |
| BR0311976A (pt) | 2005-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |