ATE424396T1 - Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamente - Google Patents

Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamente

Info

Publication number
ATE424396T1
ATE424396T1 AT03760060T AT03760060T ATE424396T1 AT E424396 T1 ATE424396 T1 AT E424396T1 AT 03760060 T AT03760060 T AT 03760060T AT 03760060 T AT03760060 T AT 03760060T AT E424396 T1 ATE424396 T1 AT E424396T1
Authority
AT
Austria
Prior art keywords
heteroarylmethylamino
medications
halogen
production process
methyl piperidine
Prior art date
Application number
AT03760060T
Other languages
English (en)
Inventor
Bernard Vacher
Bernard Bonnaud
Jean-Louis Maurel
Francis Colpaert
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Application granted granted Critical
Publication of ATE424396T1 publication Critical patent/ATE424396T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT03760060T 2002-06-18 2003-06-18 Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamente ATE424396T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0207470A FR2840900B1 (fr) 2002-06-18 2002-06-18 Nouveaux derives d'aryl[4-halogeno-4- [(heteroaryl-methylamino)-methyl]-piperidin-1-yl]-methanone, leur procede de preparation et leur utilisation a titre de medicaments

Publications (1)

Publication Number Publication Date
ATE424396T1 true ATE424396T1 (de) 2009-03-15

Family

ID=29595331

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03760060T ATE424396T1 (de) 2002-06-18 2003-06-18 Neue aryl-4-halogen-4- (heteroarylmethylamino)methyl piperidin-1-yl- methanonderivate, herstellungsverfahren und deren verwendung als medikamente

Country Status (14)

Country Link
US (1) US7547700B2 (de)
EP (1) EP1539738B1 (de)
JP (1) JP4699027B2 (de)
CN (1) CN1308325C (de)
AT (1) ATE424396T1 (de)
AU (1) AU2003258816B2 (de)
BR (1) BRPI0311976B8 (de)
CA (1) CA2489723C (de)
DE (1) DE60326468D1 (de)
ES (1) ES2321927T3 (de)
FR (1) FR2840900B1 (de)
MX (1) MXPA05000024A (de)
WO (1) WO2003106449A1 (de)
ZA (1) ZA200500467B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2852244B1 (fr) 2003-03-13 2007-09-07 Pf Medicament Utilisation de derives de pyridin-2-yl-methylamine pour la preparation d'un medicament destine au traitement des symptomes de la douleur chronique d'origine neuropathique ou psychogene
FR2891274B1 (fr) * 2005-09-27 2007-11-23 Pierre Fabre Medicament Sa Procede de preparation du (3-chloro-4-fluoro-phenyl)-(4- fluoro-4-{[(5-methyl-pyrimidin-2-ylmethyl)-amino]-methyl}- piperidin-1-yl)-methanone et nouveaux derives pyrimidiniques intermediaires.
JP2011520975A (ja) * 2008-05-19 2011-07-21 ユニヴァーシティ オブ テネシー リサーチ ファウンデーション，ザ ピリミジンの非古典的カンナビノイド化合物及び関連する使用方法
US8389534B2 (en) * 2008-05-19 2013-03-05 The University Of Tennessee Research Foundation Pyrimidine non-classical cannabinoid compounds and related methods of use
FR2946344B1 (fr) * 2009-06-05 2012-05-25 Pf Medicament Nouveaux derives d'aryl-{4-halogeno-4-[aminomethyl]-piperidin-1-yl} methanone, leur procede de preparation et leur utilisation a titre de medicaments
EP2338873A1 (de) 2009-12-22 2011-06-29 Gmeiner, Peter Neue Aminotetralinderivate
WO2018057576A1 (en) * 2016-09-22 2018-03-29 Auspex Pharmaceuticals, Inc. Deuterium-substituted pyridin- and pyrimidin-2-yl-methylamine compounds
EP3664787B1 (de) 2017-07-20 2022-07-20 Neurolixis Verwendung von selektiven serotin-5-ht1a-rezeptor-agonisten zur behandlung von nebenwirkungen von vmat-inhibitoren
WO2023144166A1 (en) 2022-01-26 2023-08-03 Neurolixis Use of serotonin 5-ht1a receptor agonists to treat diseases associated with sudden unexpected death in epilepsy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN169588B (de) * 1986-10-07 1991-11-16 Pfizer Hospital Prod
FR2755967B1 (fr) * 1996-11-21 1999-01-29 Pf Medicament Derives de la pyridin-2-yl-methylamine, leur procede de preparation et leur application comme medicaments
FR2784378B1 (fr) * 1998-10-09 2000-12-29 Pf Medicament Nouveaux derives d'aryl-(4-fluoro-4-[(2-pyridin-2-yl- ethylamino)-methyl]-piperidin-1-yl)-methanone, leur procede de preparation et leur utilisation a titre de medicaments
FR2820743B1 (fr) * 2001-02-09 2005-02-25 Pf Medicament Procede et intermediaires de synthese pour la preparation de derives de pyridin-2-yl-methylamine

Also Published As

Publication number Publication date
JP2005534668A (ja) 2005-11-17
HK1075452A1 (en) 2005-12-16
CN1675194A (zh) 2005-09-28
CA2489723A1 (fr) 2003-12-24
US7547700B2 (en) 2009-06-16
WO2003106449A1 (fr) 2003-12-24
BRPI0311976B8 (pt) 2021-05-25
US20060100244A1 (en) 2006-05-11
BRPI0311976B1 (pt) 2015-08-18
AU2003258816B2 (en) 2008-08-21
FR2840900A1 (fr) 2003-12-19
DE60326468D1 (de) 2009-04-16
CN1308325C (zh) 2007-04-04
BR0311976A (pt) 2005-03-29
EP1539738A1 (de) 2005-06-15
AU2003258816A1 (en) 2003-12-31
ZA200500467B (en) 2005-12-28
FR2840900B1 (fr) 2005-02-25
MXPA05000024A (es) 2005-04-08
JP4699027B2 (ja) 2011-06-08
EP1539738B1 (de) 2009-03-04
CA2489723C (fr) 2011-08-02
ES2321927T3 (es) 2009-06-15
WO2003106449A8 (fr) 2005-02-17

Similar Documents

Publication Publication Date Title
ATE430150T1 (de) 8-ä3-amino-piperidin-1-ylü-xanthine, deren herstellung und deren verwendung als dpp-iv hemmer
CY1109510T1 (el) Επιλεγμενοι ανταγωνιστες toy cgrp, μεθοδος για την παραγωγη τους και για τη χρηση τους ως φαρμακων
DE60330015D1 (de) Aza-bicycloalkylether und deren verwendung als alpha7-nachr agonisten
NO20064669L (no) Dipeptidylpeptidaseinhibitorer
DE60326468D1 (de) Neue aryl-4-halogen-4-(heteroarylmethylamino)methyl piperidin-1-yl-methanonderivate, herstellungsverfahren und deren verwendung als medikamente
DE602004030334D1 (de) Synthese von 5-substituierten 7-azaindolen und 7-azaindolinen
ATE359286T1 (de) Heterozyklische verbindungen, verfahren zu deren herstellung sowie deren verwendung als antibiotika
ATE422198T1 (de) Arylsulfonylnaphthalinderivate als 5ht2a- antagonisten
ATE349412T1 (de) Epothilon-synthesebausteine i: unsymmetrisch substituierte acyloine und acyloinderivate, verfahren zu deren herstellung sowie deren verwendung zur herstellung von epothilonen und epothilonderivaten
EP1428831A4 (de) Verfahren zur aufbewahrung von wasserstoff, wasserstoffeinschlussverbindung und verfahren zu deren herstellung
DE602006012801D1 (de) Verwendung von 1- benzyl-1- hydroxy-2, 3-diamino-propylaminen, 3-benzyl-3 hydroxy-2-amino-propionsäureamiden und verwandten verbindungen als analgetika
ATE316966T1 (de) Benzoxazinonderivate, deren herstellung und deren verwendung als medikamente
ATE291024T1 (de) Neue 4-aminofuropyrimidine und ihre verwendung
ATE444747T1 (de) Verfahren zur herstellung von expoxybutanol- zwischenprodukten
CY1111277T1 (el) Μεθοδος παραγωγης κιλοσταζολης
PE20110117A1 (es) Derivados de 3,5-piridina como inhibidores de renina
ATE546443T1 (de) Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze
MY144180A (en) Method for producing strontium ranelate and its hydrates
ATE553095T1 (de) Neue imidazolderivate, deren herstellung und deren verwendung als intermediate zur herstellung von arzneimitteln und pestiziden
SG158864A1 (en) Processes for preparing 4-(phenoxy-5-methyl-pyrimidin-4-yloxy)piperidine-1- carboxylic acid derivatives and related compounds
ATE525364T1 (de) Verfahren zur herstellung von 3,6-dihydro-1,3,5- triazin-derivaten
CY1105197T1 (el) Μεθοδος παραγωγης σουλφοναμιδο-υποκατεστημενων ιμιδαζοτριαζινονων
CO6150165A2 (es) Nevos derivados 5,7-disustituidos de [1,3]tiazolo[4,5-d]pirimidin-2 (3h)-ona y su uso en terapia
ATE461924T1 (de) Verfahren zur herstellung von rosuvastatin und intermediate
EP1956077A4 (de) Neuer mikroorganismus und verfahren zur carotinoidproduktion damit

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties