ATE422878T1 - Formulierungen, welche dicht und weniger dicht mit igf-i beladen sind, zur verwendung in multivesikulären liposomen - Google Patents

Formulierungen, welche dicht und weniger dicht mit igf-i beladen sind, zur verwendung in multivesikulären liposomen

Info

Publication number
ATE422878T1
ATE422878T1 AT98945974T AT98945974T ATE422878T1 AT E422878 T1 ATE422878 T1 AT E422878T1 AT 98945974 T AT98945974 T AT 98945974T AT 98945974 T AT98945974 T AT 98945974T AT E422878 T1 ATE422878 T1 AT E422878T1
Authority
AT
Austria
Prior art keywords
igf
mvls
osmolarity
liposomes
aqueous component
Prior art date
Application number
AT98945974T
Other languages
English (en)
Inventor
Bret Shirley
Maninder Hora
Qiang Ye
Nandini Katre
John Asherman
Original Assignee
Skyepharma Inc
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Skyepharma Inc, Novartis Vaccines & Diagnostic filed Critical Skyepharma Inc
Application granted granted Critical
Publication of ATE422878T1 publication Critical patent/ATE422878T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98945974T 1997-09-08 1998-09-08 Formulierungen, welche dicht und weniger dicht mit igf-i beladen sind, zur verwendung in multivesikulären liposomen ATE422878T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/925,531 US6306432B1 (en) 1997-09-08 1997-09-08 High and low load formulations of IGF-I in multivesicular liposomes

Publications (1)

Publication Number Publication Date
ATE422878T1 true ATE422878T1 (de) 2009-03-15

Family

ID=25451863

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98945974T ATE422878T1 (de) 1997-09-08 1998-09-08 Formulierungen, welche dicht und weniger dicht mit igf-i beladen sind, zur verwendung in multivesikulären liposomen

Country Status (9)

Country Link
US (1) US6306432B1 (de)
EP (1) EP1021167B1 (de)
JP (1) JP2001515852A (de)
AT (1) ATE422878T1 (de)
AU (1) AU9310098A (de)
DE (1) DE69840576D1 (de)
ES (1) ES2322974T3 (de)
PT (1) PT1021167E (de)
WO (1) WO1999012522A1 (de)

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US7141544B2 (en) * 2003-10-10 2006-11-28 Baxter International, Inc. Stabilization of pharmaceutical protein formulations with small peptides
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KR102069670B1 (ko) * 2017-03-02 2020-01-23 단디바이오사이언스 주식회사 면역활성물질을 포함하는 다중도메인캡슐, 이의 제조방법, 및 이를 포함하는 면역조절 조성물
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

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Also Published As

Publication number Publication date
JP2001515852A (ja) 2001-09-25
WO1999012522A1 (en) 1999-03-18
DE69840576D1 (de) 2009-04-02
ES2322974T3 (es) 2009-07-02
PT1021167E (pt) 2009-04-20
EP1021167A1 (de) 2000-07-26
US6306432B1 (en) 2001-10-23
AU9310098A (en) 1999-03-29
EP1021167A4 (de) 2003-04-02
EP1021167B1 (de) 2009-02-18

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