ATE417601T1 - Auf temperatur ansprechendes gel zur verzögerten freisetzung von proteinarzneistoffen - Google Patents
Auf temperatur ansprechendes gel zur verzögerten freisetzung von proteinarzneistoffenInfo
- Publication number
- ATE417601T1 ATE417601T1 AT97935238T AT97935238T ATE417601T1 AT E417601 T1 ATE417601 T1 AT E417601T1 AT 97935238 T AT97935238 T AT 97935238T AT 97935238 T AT97935238 T AT 97935238T AT E417601 T1 ATE417601 T1 AT E417601T1
- Authority
- AT
- Austria
- Prior art keywords
- delayed release
- temperature responsive
- protein drugs
- responsive gel
- percent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
- A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/679,199 US5861174A (en) | 1996-07-12 | 1996-07-12 | Temperature sensitive gel for sustained delivery of protein drugs |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE417601T1 true ATE417601T1 (de) | 2009-01-15 |
Family
ID=24725962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97935238T ATE417601T1 (de) | 1996-07-12 | 1997-07-11 | Auf temperatur ansprechendes gel zur verzögerten freisetzung von proteinarzneistoffen |
Country Status (13)
Country | Link |
---|---|
US (2) | US5861174A (de) |
EP (1) | EP0910342B1 (de) |
JP (1) | JP2000514811A (de) |
KR (1) | KR20000023751A (de) |
CN (1) | CN1230108A (de) |
AT (1) | ATE417601T1 (de) |
AU (1) | AU3822497A (de) |
BR (1) | BR9712969A (de) |
CA (1) | CA2260967A1 (de) |
DE (1) | DE69739169D1 (de) |
ES (1) | ES2318860T3 (de) |
IL (1) | IL127976A0 (de) |
WO (1) | WO1998002142A1 (de) |
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DE60117043T2 (de) * | 2000-11-22 | 2006-07-13 | Rxkinetix, Inc., Louisville | Behandlung von mukositis |
US6565530B2 (en) | 2001-02-28 | 2003-05-20 | Scimed Life Systems, Inc. | Immobilizing objects in the body |
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EP2683328B1 (de) | 2011-03-07 | 2017-11-08 | Wake Forest University Health Sciences | Freisetzungssystem |
BR112013024863A2 (pt) | 2011-03-28 | 2016-12-20 | Yissum Res Dev Co | formulação injetável de liberação sustentada |
KR20160047490A (ko) | 2013-08-27 | 2016-05-02 | 오토노미, 인코포레이티드 | 소아 귀 질환의 치료 |
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EP3164115A4 (de) | 2014-07-03 | 2017-05-17 | Otonomy, Inc. | Sterilisation einer ciprofloxacinzusammensetzung |
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EP3723775A4 (de) | 2017-12-15 | 2022-04-13 | Solarea Bio, Inc. | Mikrobielle zusammensetzungen und verfahren zur behandlung von typ-2-diabetes, fettleibigkeit und stoffwechselsyndrom |
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-
1996
- 1996-07-12 US US08/679,199 patent/US5861174A/en not_active Expired - Lifetime
-
1997
- 1997-07-11 AT AT97935238T patent/ATE417601T1/de not_active IP Right Cessation
- 1997-07-11 AU AU38224/97A patent/AU3822497A/en not_active Abandoned
- 1997-07-11 CN CN97197798A patent/CN1230108A/zh active Pending
- 1997-07-11 DE DE69739169T patent/DE69739169D1/de not_active Expired - Lifetime
- 1997-07-11 CA CA002260967A patent/CA2260967A1/en not_active Abandoned
- 1997-07-11 JP JP10506356A patent/JP2000514811A/ja active Pending
- 1997-07-11 ES ES97935238T patent/ES2318860T3/es not_active Expired - Lifetime
- 1997-07-11 WO PCT/US1997/013479 patent/WO1998002142A1/en not_active Application Discontinuation
- 1997-07-11 IL IL12797697A patent/IL127976A0/xx unknown
- 1997-07-11 EP EP97935238A patent/EP0910342B1/de not_active Expired - Lifetime
- 1997-07-11 BR BR9712969-0A patent/BR9712969A/pt not_active Application Discontinuation
-
1999
- 1999-01-12 KR KR1019997000215A patent/KR20000023751A/ko not_active Application Discontinuation
- 1999-01-15 US US09/232,288 patent/US6482435B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU3822497A (en) | 1998-02-09 |
US5861174A (en) | 1999-01-19 |
KR20000023751A (ko) | 2000-04-25 |
BR9712969A (pt) | 2002-02-05 |
CA2260967A1 (en) | 1998-01-22 |
US6482435B1 (en) | 2002-11-19 |
EP0910342A1 (de) | 1999-04-28 |
JP2000514811A (ja) | 2000-11-07 |
IL127976A0 (en) | 1999-11-30 |
ES2318860T3 (es) | 2009-05-01 |
WO1998002142A1 (en) | 1998-01-22 |
EP0910342A4 (de) | 2006-03-22 |
CN1230108A (zh) | 1999-09-29 |
DE69739169D1 (de) | 2009-01-29 |
EP0910342B1 (de) | 2008-12-17 |
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