ATE416385T1 - Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen - Google Patents

Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen

Info

Publication number
ATE416385T1
ATE416385T1 AT01973567T AT01973567T ATE416385T1 AT E416385 T1 ATE416385 T1 AT E416385T1 AT 01973567 T AT01973567 T AT 01973567T AT 01973567 T AT01973567 T AT 01973567T AT E416385 T1 ATE416385 T1 AT E416385T1
Authority
AT
Austria
Prior art keywords
phosphorylation
protein
proteins
quantifying
tau
Prior art date
Application number
AT01973567T
Other languages
English (en)
Inventor
Kevin Reagan
Erik Schaeffer
Jimin Wang
Original Assignee
Invitrogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invitrogen Corp filed Critical Invitrogen Corp
Application granted granted Critical
Publication of ATE416385T1 publication Critical patent/ATE416385T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT01973567T 2000-09-27 2001-09-27 Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen ATE416385T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23562000P 2000-09-27 2000-09-27

Publications (1)

Publication Number Publication Date
ATE416385T1 true ATE416385T1 (de) 2008-12-15

Family

ID=22886277

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01973567T ATE416385T1 (de) 2000-09-27 2001-09-27 Verfahren zur quantifizierung der phosphokinaseaktivität auf proteinen

Country Status (7)

Country Link
US (4) US20030162230A1 (de)
EP (3) EP2298814A3 (de)
JP (2) JP2004516823A (de)
AT (1) ATE416385T1 (de)
CA (1) CA2423979C (de)
DE (1) DE60136840D1 (de)
WO (1) WO2002027017A2 (de)

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US20030162230A1 (en) * 2000-09-27 2003-08-28 Reagan Kevin J. Method for quantifying phosphokinase activity on proteins
GB0208104D0 (en) 2002-04-09 2002-05-22 Univ Dundee Method
US7217796B2 (en) 2002-05-24 2007-05-15 Schering Corporation Neutralizing human anti-IGFR antibody
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
EP1668146B1 (de) * 2003-09-25 2014-11-12 Life Technologies Corporation Homogene populationen von molekülen
JP2007510434A (ja) 2003-11-12 2007-04-26 シェーリング　コーポレイション 多重遺伝子発現のためのプラスミドシステム
PE20050928A1 (es) 2003-11-21 2005-11-08 Schering Corp Combinaciones terapeuticas de anticuerpo anti-igfr1
US7811562B2 (en) 2004-12-03 2010-10-12 Schering Corporation Biomarkers for pre-selection of patients for anti-IGF1R therapy
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
WO2007005605A2 (en) * 2005-07-01 2007-01-11 Washington University In St. Louis Phosphospecific chemokine receptor antibodies
WO2007133688A2 (en) * 2006-05-12 2007-11-22 Cell Signaling Technology, Inc. Reagents for the detection of tyrosine phosphorylation in brain ischemia signaling pathways
US20100160339A1 (en) * 2007-05-21 2010-06-24 Mayo Foundation For Medical Education And Research Treating pancreatitis
KR101612442B1 (ko) * 2008-05-13 2016-04-15 삼성전자주식회사 컨텐츠 시청 제한 정보의 제공 및 이용을 위한 방법 및장치
WO2011120082A1 (en) * 2010-03-29 2011-10-06 Medvet Science Pty. Ltd. A method of modulating protein 14-3-3 functionality by facilitating or inhibiting phosphorylation
US20130164274A1 (en) * 2010-09-07 2013-06-27 Stephen G. Marx Kit for monitoring, detecting and staging gvhd
US20170016900A1 (en) 2010-09-07 2017-01-19 Stephen G. Marx Kit for monitoring, detecting and staging gvhd
US9200068B2 (en) 2012-12-18 2015-12-01 Regents Of The University Of Minnesota Compositions and methods related to tauopathy
RS60031B1 (sr) 2013-12-20 2020-04-30 Hoffmann La Roche Humanizovana anti-tau(ps422) antitela i načini upotrebe
EP3088898B1 (de) * 2013-12-27 2024-02-07 National University Corporation Tokyo Medical and Dental University Verfahren zur diagnose von morbus alzheimer und frontotemporaler lobärer degeneration, diagnosemittel, therapeutisches mittel und screening-verfahren für die besagten mittel
CN106062560A (zh) * 2014-03-31 2016-10-26 默克专利股份公司 使用特异性抗体检测蛋白质修饰的方法
AR100978A1 (es) 2014-06-26 2016-11-16 Hoffmann La Roche LANZADERAS CEREBRALES DE ANTICUERPO HUMANIZADO ANTI-Tau(pS422) Y USOS DE LAS MISMAS
AR105089A1 (es) 2015-06-24 2017-09-06 Hoffmann La Roche ANTICUERPOS ANTI-TAU(pS422) HUMANIZADOS Y MÉTODOS DE UTILIZACIÓN
JO3711B1 (ar) 2015-07-13 2021-01-31 H Lundbeck As أجسام مضادة محددة لبروتين تاو وطرق استعمالها
PE20190227A1 (es) 2016-07-12 2019-02-13 H Lundbeck As Anticuerpos especificos para la tau hiperfosforilada y sus metodos de uso
EP3324187B1 (de) * 2016-11-21 2020-03-11 Ruhr-Universität Bochum Kombinations-assay für die differenzialdiagnose der alzheimer-krankheit
EP3565836A1 (de) 2017-01-04 2019-11-13 H. Lundbeck A/S Für hypophosphoryliertes tau spezifische antikörper zur behandlung von augenerkrankungen
JP7317039B2 (ja) * 2017-12-18 2023-07-28 イエール ユニバーシティ 線維症を処置するための化合物および組成物
EP3762414A4 (de) 2018-03-05 2022-01-05 Janssen Pharmaceutica NV Tests zum nachweis von neurodegeneration
US11085935B2 (en) 2018-05-03 2021-08-10 Washington University Methods of treating based on site-specific tau phosphorylation

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ATE497164T1 (de) * 1999-06-09 2011-02-15 Molecular Devices Inc Testverfahren zur messung der phosphorylierung
EP1207395A4 (de) * 1999-08-04 2003-08-13 Med & Biological Lab Co Ltd Verfahren zum messen der kinaseaktivität eines cyclin/cdk-komplexes
WO2001055725A2 (en) * 2000-01-24 2001-08-02 Innogenetics N.V. Diagnosis of tauopathies determining tau/phospho-tau ratio
US20030166016A1 (en) 2000-04-28 2003-09-04 Foster Barbara A. Assay methods for cyclin dependent kinases
US20030162230A1 (en) 2000-09-27 2003-08-28 Reagan Kevin J. Method for quantifying phosphokinase activity on proteins

Also Published As

Publication number Publication date
CA2423979A1 (en) 2002-04-04
EP2040078A1 (de) 2009-03-25
WO2002027017A2 (en) 2002-04-04
US20030162230A1 (en) 2003-08-28
EP2298814A2 (de) 2011-03-23
US20090104628A1 (en) 2009-04-23
DE60136840D1 (de) 2009-01-15
US7888050B2 (en) 2011-02-15
US20120135426A1 (en) 2012-05-31
JP2004516823A (ja) 2004-06-10
EP1328812A2 (de) 2003-07-23
WO2002027017A3 (en) 2003-01-16
JP2006225396A (ja) 2006-08-31
EP1328812B1 (de) 2008-12-03
CA2423979C (en) 2012-03-06
US20110165588A1 (en) 2011-07-07
EP2298814A3 (de) 2012-05-30
US8114617B2 (en) 2012-02-14

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