ATE406379T1 - Einschlusskomplexe von perindopril - Google Patents

Einschlusskomplexe von perindopril

Info

Publication number
ATE406379T1
ATE406379T1 AT05700892T AT05700892T ATE406379T1 AT E406379 T1 ATE406379 T1 AT E406379T1 AT 05700892 T AT05700892 T AT 05700892T AT 05700892 T AT05700892 T AT 05700892T AT E406379 T1 ATE406379 T1 AT E406379T1
Authority
AT
Austria
Prior art keywords
perindopril
inclusion complexes
complexes
inclusion
perindopril erbumine
Prior art date
Application number
AT05700892T
Other languages
English (en)
Inventor
Rudolf Rucman
Original Assignee
Lek Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals filed Critical Lek Pharmaceuticals
Application granted granted Critical
Publication of ATE406379T1 publication Critical patent/ATE406379T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Glass Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05700892T 2004-01-14 2005-01-13 Einschlusskomplexe von perindopril ATE406379T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200400011A SI21703A (en) 2004-01-14 2004-01-14 Inclusion complexes of perindopril, procedure of their preparation, pharmaceutical compositions containing these complexes and their application in treatment of hypertensia

Publications (1)

Publication Number Publication Date
ATE406379T1 true ATE406379T1 (de) 2008-09-15

Family

ID=34793532

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05700892T ATE406379T1 (de) 2004-01-14 2005-01-13 Einschlusskomplexe von perindopril

Country Status (7)

Country Link
EP (2) EP1709066B1 (de)
AT (1) ATE406379T1 (de)
DE (1) DE602005009319D1 (de)
PL (1) PL1709066T3 (de)
RU (1) RU2372353C2 (de)
SI (2) SI21703A (de)
WO (1) WO2005068490A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1948224T1 (sl) * 2005-11-17 2014-07-31 Silverstone Pharma Est. Stabilna formulacija amorfnih perindoprilnih soli, postopek za njihovo pripravo, posebno industrijsko pripravo, in njihova uporaba pri zdravljenju hipertenzije
EP1815857A1 (de) 2006-02-02 2007-08-08 LEK Pharmaceuticals D.D. Pharmazeutische Zusammensetzung enthaltend Perindopril
WO2008125134A1 (en) * 2007-04-13 2008-10-23 Helm Ag Process for the preparation of perindopril-tert-butylamine adsorbates
SI22542A (sl) * 2007-06-04 2008-12-31 Diagen D.O.O. Stabilna formulacija amorfnih soli perindoprila, postopek za njeno pripravo v industrijskem merilu in njena uporaba za zdravljenje hipertenzije
SI22543A (sl) 2007-06-27 2008-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove soli perindoprila

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4508729A (en) 1979-12-07 1985-04-02 Adir Substituted iminodiacids, their preparation and pharmaceutical compositions containing them
FR2503155A2 (fr) 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2620709B1 (fr) * 1987-09-17 1990-09-07 Adir Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese
SI9500140A (en) 1995-04-24 1996-10-31 Genesis Para La Investigacion Novel n-sulfoxy anhydrides, process for the preparation thereof and its use for the preparation of bioactive substances having ace inhibitory action
UA57734C2 (uk) * 1996-05-07 2003-07-15 Пфайзер Інк. Комплекси включення арилгетероциклічних солей
FR2811319B1 (fr) 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline beta du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811320B1 (fr) 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2811318B1 (fr) 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline gamma du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent
HRP20000765A2 (en) * 2000-11-10 2002-06-30 Pliva D D Compositions of n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridylsulfonamide and cyclic oligosaccharides with increased release
AR036187A1 (es) 2001-07-24 2004-08-18 Adir Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario
SI21506A (sl) * 2003-05-08 2004-12-31 LEK farmacevtska dru�ba d.d. Postopek za pripravo perindoprila

Also Published As

Publication number Publication date
DE602005009319D1 (de) 2008-10-09
SI1709066T1 (sl) 2009-02-28
RU2006129349A (ru) 2008-02-20
RU2372353C2 (ru) 2009-11-10
PL1709066T3 (pl) 2009-02-27
EP1709066A1 (de) 2006-10-11
WO2005068490A1 (en) 2005-07-28
EP2003142A1 (de) 2008-12-17
SI21703A (en) 2005-08-31
EP1709066B1 (de) 2008-08-27

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Legal Events

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