ATE402714T1 - Stabilisierung von pharmazeutischen epo- formulierungen mit kleinen peptiden - Google Patents
Stabilisierung von pharmazeutischen epo- formulierungen mit kleinen peptidenInfo
- Publication number
- ATE402714T1 ATE402714T1 AT04784802T AT04784802T ATE402714T1 AT E402714 T1 ATE402714 T1 AT E402714T1 AT 04784802 T AT04784802 T AT 04784802T AT 04784802 T AT04784802 T AT 04784802T AT E402714 T1 ATE402714 T1 AT E402714T1
- Authority
- AT
- Austria
- Prior art keywords
- gly
- ala
- stabilization
- pharmaceutical
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/683,549 US7141544B2 (en) | 2003-10-10 | 2003-10-10 | Stabilization of pharmaceutical protein formulations with small peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE402714T1 true ATE402714T1 (de) | 2008-08-15 |
Family
ID=34422759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04784802T ATE402714T1 (de) | 2003-10-10 | 2004-09-22 | Stabilisierung von pharmazeutischen epo- formulierungen mit kleinen peptiden |
Country Status (13)
Country | Link |
---|---|
US (1) | US7141544B2 (de) |
EP (1) | EP1670495B1 (de) |
JP (1) | JP2007537988A (de) |
CN (1) | CN100423772C (de) |
AT (1) | ATE402714T1 (de) |
BR (1) | BRPI0415213A (de) |
CA (1) | CA2540324A1 (de) |
DE (1) | DE602004015485D1 (de) |
DK (1) | DK1670495T3 (de) |
ES (1) | ES2311861T3 (de) |
MX (1) | MXPA06003913A (de) |
PL (1) | PL1670495T3 (de) |
WO (1) | WO2005037302A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1765411B2 (de) * | 2004-06-30 | 2017-10-11 | Nektar Therapeutics | Polymer-faktor-ix-konjugate |
AU2006295340B2 (en) | 2005-08-05 | 2010-11-11 | Amgen Inc. | Stable aqueous protein or antibody pharmaceutical formulations and their preparation |
US20070155672A1 (en) * | 2006-01-05 | 2007-07-05 | Markus Voges | Sterilized peritoneal dialysis solutions containing heparin |
US20100266569A1 (en) * | 2007-11-15 | 2010-10-21 | Mark Zylka | Prostatic acid phosphatase for the treatment of pain |
JP2011116752A (ja) * | 2009-10-29 | 2011-06-16 | Jcr Pharmaceuticals Co Ltd | エリスロポエチン含有水性液剤 |
US20120295935A1 (en) * | 2010-01-21 | 2012-11-22 | Michael Frid | Mixed aminal pharmaceutical compositions and uses thereof |
WO2011097335A2 (en) | 2010-02-04 | 2011-08-11 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase variants and methods of using compositions thereof |
CA2853791C (en) * | 2011-10-28 | 2017-10-24 | Ruey J. Yu | N-acyldipeptide derivatives and their uses |
CN104080441B (zh) | 2011-11-30 | 2020-02-28 | 3M创新有限公司 | 包括肽治疗剂和氨基酸的微针装置、制备和使用其的方法 |
CN103880919B (zh) * | 2014-03-06 | 2016-06-29 | 福州大学 | 一种金属螯合蛋白水解肽的制备方法 |
BR112017013696B1 (pt) * | 2014-12-23 | 2024-01-02 | Avon Products, Inc | Método para diminuir o aparecimento de sinais dermatológicos do envelhecimento |
IL255148B2 (en) | 2015-04-29 | 2023-04-01 | Radius Pharmaceuticals Inc | 1901 rad for use in a method to inhibit a cancerous growth or induce tumor regression in a patient who is resistant to the drug and/or has cancer positive for an estrogen receptor alpha mutation |
KR102322802B1 (ko) | 2017-01-05 | 2021-11-04 | 래디어스 파마슈티컬스, 인코포레이티드 | Rad1901-2hcl의 다형 형태 |
IL279853B1 (en) | 2018-07-04 | 2024-09-01 | Radius Pharmaceuticals Inc | Polymorphic forms of RAD 1901-2HCL |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57112367A (en) * | 1980-12-29 | 1982-07-13 | Sankyo Co Ltd | Preparation of stable aqueous solution of compound having thiol group |
US4703008A (en) * | 1983-12-13 | 1987-10-27 | Kiren-Amgen, Inc. | DNA sequences encoding erythropoietin |
JPS6217A (ja) * | 1985-02-14 | 1987-01-06 | Chugai Pharmaceut Co Ltd | 安定な活性型ビタミンd3類製剤 |
DK173067B1 (da) * | 1986-06-27 | 1999-12-13 | Univ Washington | Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa |
US5366875A (en) * | 1986-07-01 | 1994-11-22 | Genetics Institute, Inc. | Methods for producing BMP-7 proteins |
ZA874681B (en) * | 1986-07-01 | 1988-04-27 | Genetics Inst | Novel osteoinductive factors |
DE3729863A1 (de) * | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
WO1993000050A1 (en) * | 1991-06-21 | 1993-01-07 | Genetics Institute, Inc. | Pharmaceutical formulations of osteogenic proteins |
US5661125A (en) * | 1992-08-06 | 1997-08-26 | Amgen, Inc. | Stable and preserved erythropoietin compositions |
DE4242919A1 (de) * | 1992-12-18 | 1994-06-23 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von lagerstabilen wässrigen pharmazeutischen Zubereitungen von G-CSF |
US5652216A (en) * | 1994-05-26 | 1997-07-29 | Novo Nordisk A/S | Pharmaceutical preparation |
ES2137551T3 (es) * | 1994-11-17 | 1999-12-16 | Alza Corp | Dispositivo para mejorar la administracion de un agente por electrotransporte. |
US5705482A (en) * | 1995-01-13 | 1998-01-06 | Novo Nordisk A/S | Pharmaceutical formulation |
JP3543144B2 (ja) * | 1995-03-11 | 2004-07-14 | 国際試薬株式会社 | 臨床検査用製剤 |
JP3490816B2 (ja) * | 1995-10-31 | 2004-01-26 | 株式会社コーセー | 皮膚外用剤 |
US20030162711A1 (en) * | 1996-04-24 | 2003-08-28 | Soren Bjorn | Pharmaceutical formulation |
TWI240627B (en) * | 1996-04-26 | 2005-10-01 | Chugai Pharmaceutical Co Ltd | Erythropoietin solution preparation |
US6605699B1 (en) | 1997-01-21 | 2003-08-12 | Human Genome Sciences, Inc. | Galectin-11 polypeptides |
US6306432B1 (en) * | 1997-09-08 | 2001-10-23 | Chiron Corporation | High and low load formulations of IGF-I in multivesicular liposomes |
WO1999024071A1 (en) * | 1997-11-12 | 1999-05-20 | Alza Corporation | Method for decreasing self-association of polypeptides |
JP3722268B2 (ja) * | 1998-09-03 | 2005-11-30 | 栗田工業株式会社 | 抗菌性組成物 |
US6469091B2 (en) | 1999-01-14 | 2002-10-22 | Idemitsu Petrochemical Co., Ltd. | Polyarylene sulfide resin composition |
NZ515380A (en) | 1999-04-09 | 2003-10-31 | Ortho Mcneil Pharm Inc | Aqueous stable preserved pharmaceutical compositions of erythropoietin |
US6624289B1 (en) * | 1999-06-16 | 2003-09-23 | Saint Louis University | Region of factor IXa protease domain that interacts with factor VIIIa and methods therefor |
AU783306B2 (en) | 1999-10-04 | 2005-10-13 | Novartis Vaccines And Diagnostics, Inc. | Stabilized liquid polypeptide-containing pharmaceutical compositions |
US6585957B1 (en) * | 2000-01-25 | 2003-07-01 | Aeropharm Technology Incorporated | Medicinal aerosol formulation |
WO2001057184A2 (en) * | 2000-02-01 | 2001-08-09 | Vanderbilt University | Use of platelet activity modulators for inhibiting complement activation |
CA2398567A1 (en) * | 2000-02-11 | 2001-08-16 | Praecis Pharmaceuticals Incorporated | Methods for enhancing the bioavailability of a drug |
AU2001236005A1 (en) * | 2000-02-29 | 2001-09-12 | Chugai Seiyaku Kabushiki Kaisha | Preparations stabilized over long time |
US7078376B1 (en) | 2000-08-11 | 2006-07-18 | Baxter Healthcare S.A. | Therapeutic methods for treating subjects with a recombinant erythropoietin having high activity and reduced side effects |
US20030104996A1 (en) | 2001-08-30 | 2003-06-05 | Tiansheng Li | L-methionine as a stabilizer for NESP/EPO in HSA-free formulations |
WO2005051979A1 (en) * | 2003-02-21 | 2005-06-09 | Akzo Nobel N.V. | Prevention and/or delay of peptide/protein carbamylation in urea solutions utilizing non-ethylene diamine like compounds |
-
2003
- 2003-10-10 US US10/683,549 patent/US7141544B2/en not_active Expired - Fee Related
-
2004
- 2004-09-22 PL PL04784802T patent/PL1670495T3/pl unknown
- 2004-09-22 CN CNB2004800289995A patent/CN100423772C/zh not_active Expired - Fee Related
- 2004-09-22 WO PCT/US2004/031094 patent/WO2005037302A1/en active Application Filing
- 2004-09-22 BR BRPI0415213-1A patent/BRPI0415213A/pt not_active IP Right Cessation
- 2004-09-22 JP JP2006533968A patent/JP2007537988A/ja not_active Revoked
- 2004-09-22 CA CA002540324A patent/CA2540324A1/en not_active Abandoned
- 2004-09-22 MX MXPA06003913A patent/MXPA06003913A/es active IP Right Grant
- 2004-09-22 DK DK04784802T patent/DK1670495T3/da active
- 2004-09-22 ES ES04784802T patent/ES2311861T3/es not_active Expired - Lifetime
- 2004-09-22 DE DE602004015485T patent/DE602004015485D1/de not_active Expired - Lifetime
- 2004-09-22 AT AT04784802T patent/ATE402714T1/de active
- 2004-09-22 EP EP04784802A patent/EP1670495B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
MXPA06003913A (es) | 2006-06-27 |
WO2005037302A1 (en) | 2005-04-28 |
US20050080011A1 (en) | 2005-04-14 |
DE602004015485D1 (de) | 2008-09-11 |
ES2311861T3 (es) | 2009-02-16 |
CN100423772C (zh) | 2008-10-08 |
KR20070000394A (ko) | 2007-01-02 |
CA2540324A1 (en) | 2005-04-28 |
EP1670495B1 (de) | 2008-07-30 |
CN1863544A (zh) | 2006-11-15 |
BRPI0415213A (pt) | 2006-12-05 |
DK1670495T3 (da) | 2008-10-13 |
US7141544B2 (en) | 2006-11-28 |
EP1670495A1 (de) | 2006-06-21 |
PL1670495T3 (pl) | 2009-03-31 |
JP2007537988A (ja) | 2007-12-27 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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