ATE400586T1 - Rezeptoren für das humane interleukin-12 - Google Patents

Rezeptoren für das humane interleukin-12

Info

Publication number
ATE400586T1
ATE400586T1 AT01127361T AT01127361T ATE400586T1 AT E400586 T1 ATE400586 T1 AT E400586T1 AT 01127361 T AT01127361 T AT 01127361T AT 01127361 T AT01127361 T AT 01127361T AT E400586 T1 ATE400586 T1 AT E400586T1
Authority
AT
Austria
Prior art keywords
receptor
receptors
binding
complex
human interleukin
Prior art date
Application number
AT01127361T
Other languages
English (en)
Inventor
Ulrich Andreas Gubler
David Howard Presky
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE400586T1 publication Critical patent/ATE400586T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT01127361T 1995-08-01 1996-07-23 Rezeptoren für das humane interleukin-12 ATE400586T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US170195P 1995-08-01 1995-08-01
US1867496P 1996-05-30 1996-05-30

Publications (1)

Publication Number Publication Date
ATE400586T1 true ATE400586T1 (de) 2008-07-15

Family

ID=26669384

Family Applications (2)

Application Number Title Priority Date Filing Date
AT96111807T ATE314468T1 (de) 1995-08-01 1996-07-23 Interleukin-12-beta-rezeptoren mit niedriger bindungsaffinität
AT01127361T ATE400586T1 (de) 1995-08-01 1996-07-23 Rezeptoren für das humane interleukin-12

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT96111807T ATE314468T1 (de) 1995-08-01 1996-07-23 Interleukin-12-beta-rezeptoren mit niedriger bindungsaffinität

Country Status (8)

Country Link
US (3) US5840530A (de)
EP (3) EP1243597B1 (de)
JP (1) JP2948150B2 (de)
AT (2) ATE314468T1 (de)
DE (2) DE69635639T2 (de)
DK (2) DK1243597T3 (de)
ES (2) ES2305024T3 (de)
PT (1) PT1243597E (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046012A (en) * 1993-07-19 2000-04-04 Hoffmann-La Roche Inc. Antibody to IL-12 receptor
US6830751B1 (en) * 1994-03-14 2004-12-14 Genetics Institute, Llc Use of IL-12 antagonists in the treatment of rheumatoid arthritis
WO1998022137A1 (en) * 1996-11-15 1998-05-28 The Kennedy Institute Of Rheumatology SUPPRESSION OF TNF α AND IL-12 IN THERAPY
WO1999025737A1 (en) * 1997-11-19 1999-05-27 Tanox Pharma B.V. Compositions and methods for treatment of autoimmune diseases, using a monoclonal antibody to the interleukin-12 beta2-chain
ES2226335T3 (es) 1998-01-23 2005-03-16 Immunex Corporation Receooctires de uk.18.
US6800460B1 (en) 1999-03-11 2004-10-05 Schering Corporation Mammalian cytokine complexes
EP1942114A3 (de) * 1999-03-11 2008-08-27 Schering Corporation Säuger-Zytokine, zugehörige Reagenzien und Verfahren
AU767068B2 (en) * 1999-06-11 2003-10-30 Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of leptin activity
US20020199218A1 (en) * 1999-08-19 2002-12-26 Daphne Goring Proline-rich extensin-like receptor kinases
US6346247B1 (en) 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
MXPA03003188A (es) * 2000-10-11 2004-12-03 Biotechnology Res & Dev Clonacion y secuencia de las cadenas de beta-1 y beta-2 del receptor de interlucina-12 porcina.
CA2364983A1 (en) * 2000-12-13 2002-06-13 John R. Coleman Nucleic acid molecules and polypeptides for catabolism of abscisic acid
NZ570709A (en) * 2003-06-13 2010-04-30 Univ Pennsylvania Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same
US20070178520A1 (en) * 2004-02-27 2007-08-02 Barbara Wolff-Winiski Screening assay for modulators of interaction between interleukin-12 and/or -23 with their receptors
US8784807B2 (en) 2006-09-22 2014-07-22 St. Jude Children's Research Hospital Method of inhibiting regulatory T-cell activity by administering an antibody that inhibits interleukin 35
US20130183326A9 (en) * 2009-11-20 2013-07-18 St. Jude Children's Research Hospital Methods and compositions for modulating the activity of the interleukin-35 receptor complex
US20250152716A1 (en) * 2022-02-18 2025-05-15 The Regents Of The University Of California Improved primary human nk cell expansion and function by chimeric cytokine receptor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536657A (en) * 1993-07-19 1996-07-16 Hoffmann-La Roche Inc. Recombinant DNA encoding human receptor for interleukin-12
EP0638644A1 (de) * 1993-07-19 1995-02-15 F. Hoffmann-La Roche Ag Interleukin-12 Rezeptoren und Antikörper

Also Published As

Publication number Publication date
EP1243597B1 (de) 2008-07-09
EP1243597A3 (de) 2004-05-06
EP1950226A3 (de) 2010-08-11
EP1243597A2 (de) 2002-09-25
DK1243597T3 (da) 2008-09-22
ES2305024T3 (es) 2008-11-01
EP0759466B1 (de) 2005-12-28
US5852176A (en) 1998-12-22
PT1243597E (pt) 2008-10-17
US5919903A (en) 1999-07-06
US5840530A (en) 1998-11-24
JP2948150B2 (ja) 1999-09-13
DE69635639D1 (de) 2006-02-02
EP1950226A2 (de) 2008-07-30
DE69635639T2 (de) 2006-09-14
ATE314468T1 (de) 2006-01-15
JPH09132598A (ja) 1997-05-20
EP0759466A3 (de) 1997-05-28
DK0759466T3 (da) 2006-05-15
EP0759466A2 (de) 1997-02-26
ES2255067T3 (es) 2006-06-16
DE69637599D1 (de) 2008-08-21

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