PT1243597E - Receptores para interleucina-12 humana - Google Patents

Receptores para interleucina-12 humana Download PDF

Info

Publication number
PT1243597E
PT1243597E PT01127361T PT01127361T PT1243597E PT 1243597 E PT1243597 E PT 1243597E PT 01127361 T PT01127361 T PT 01127361T PT 01127361 T PT01127361 T PT 01127361T PT 1243597 E PT1243597 E PT 1243597E
Authority
PT
Portugal
Prior art keywords
receptor
receptors
binding
complex
human interleukin
Prior art date
Application number
PT01127361T
Other languages
English (en)
Inventor
Ulrich Andreas Gubler
David Howard Presky
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PT1243597E publication Critical patent/PT1243597E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT01127361T 1995-08-01 1996-07-23 Receptores para interleucina-12 humana PT1243597E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US170195P 1995-08-01 1995-08-01
US1867496P 1996-05-30 1996-05-30

Publications (1)

Publication Number Publication Date
PT1243597E true PT1243597E (pt) 2008-10-17

Family

ID=26669384

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01127361T PT1243597E (pt) 1995-08-01 1996-07-23 Receptores para interleucina-12 humana

Country Status (8)

Country Link
US (3) US5840530A (pt)
EP (3) EP1950226A3 (pt)
JP (1) JP2948150B2 (pt)
AT (2) ATE400586T1 (pt)
DE (2) DE69637599D1 (pt)
DK (2) DK0759466T3 (pt)
ES (2) ES2305024T3 (pt)
PT (1) PT1243597E (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046012A (en) * 1993-07-19 2000-04-04 Hoffmann-La Roche Inc. Antibody to IL-12 receptor
US6706264B1 (en) 1994-03-14 2004-03-16 Genetics Institute, Llc Use of IL-12 antagonists in the treatment of conditions promoted by an increase in levels of IFN-y
DK0936923T3 (da) * 1996-11-15 2004-04-26 Kennedy Inst Of Rheumatology Undertrykkelse af TNFalpha og IL-12 ved terapi
WO1999025737A1 (en) * 1997-11-19 1999-05-27 Tanox Pharma B.V. Compositions and methods for treatment of autoimmune diseases, using a monoclonal antibody to the interleukin-12 beta2-chain
ES2226335T3 (es) * 1998-01-23 2005-03-16 Immunex Corporation Receooctires de uk.18.
CA2366706A1 (en) * 1999-03-11 2000-09-14 Schering Corporation Mammalian cytokines; related reagents and methods
US6800460B1 (en) 1999-03-11 2004-10-05 Schering Corporation Mammalian cytokine complexes
AU767068B2 (en) * 1999-06-11 2003-10-30 Baylor College Of Medicine Methods and compositions for control of bone formation via modulation of leptin activity
US20020199218A1 (en) * 1999-08-19 2002-12-26 Daphne Goring Proline-rich extensin-like receptor kinases
US6346247B1 (en) 1999-10-28 2002-02-12 Promega Corporation Prevention and treatment of autoimmune disease with luminally administered polyclonal antibodies
JP2004511231A (ja) * 2000-10-11 2004-04-15 バイオテクノロジー　リサーチ　アンド　ディベロップメント　コーポレイション ブタインターロイキン−１２レセプターのβ−１鎖およびβ−２鎖のクローニングならびに配列決定
CA2364983A1 (en) * 2000-12-13 2002-06-13 John R. Coleman Nucleic acid molecules and polypeptides for catabolism of abscisic acid
NZ570709A (en) 2003-06-13 2010-04-30 Univ Pennsylvania Nucleic acid sequences encoding and compositions comprising IgE signal peptide and/or IL-15 and methods for using the same
WO2005085866A1 (en) * 2004-02-27 2005-09-15 Novartis Ag Screening assay for modulators of interaction between interleukin-12 and/or -23 with their receptors
EP2066693A2 (en) 2006-09-22 2009-06-10 St. Jude Children's Research Hospital Modulating regulatory t cell activity via interleukin 35
US20130183326A9 (en) * 2009-11-20 2013-07-18 St. Jude Children's Research Hospital Methods and compositions for modulating the activity of the interleukin-35 receptor complex
WO2023159162A2 (en) * 2022-02-18 2023-08-24 The Regents Of The University Of California Improved primary human nk cell expansion and function by chimeric cytokine receptor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0638644A1 (en) 1993-07-19 1995-02-15 F. Hoffmann-La Roche Ag Receptors of interleukin-12 and antibodies
US5536657A (en) * 1993-07-19 1996-07-16 Hoffmann-La Roche Inc. Recombinant DNA encoding human receptor for interleukin-12

Also Published As

Publication number Publication date
EP1243597A3 (en) 2004-05-06
JP2948150B2 (ja) 1999-09-13
JPH09132598A (ja) 1997-05-20
EP0759466A3 (en) 1997-05-28
ATE314468T1 (de) 2006-01-15
US5919903A (en) 1999-07-06
US5852176A (en) 1998-12-22
ATE400586T1 (de) 2008-07-15
DE69637599D1 (de) 2008-08-21
ES2255067T3 (es) 2006-06-16
DE69635639D1 (de) 2006-02-02
EP1950226A2 (en) 2008-07-30
EP1243597B1 (en) 2008-07-09
US5840530A (en) 1998-11-24
DE69635639T2 (de) 2006-09-14
ES2305024T3 (es) 2008-11-01
DK0759466T3 (da) 2006-05-15
DK1243597T3 (da) 2008-09-22
EP0759466B1 (en) 2005-12-28
EP1243597A2 (en) 2002-09-25
EP1950226A3 (en) 2010-08-11
EP0759466A2 (en) 1997-02-26

Similar Documents

Publication Publication Date Title
PT1243597E (pt) Receptores para interleucina-12 humana
EP1798239A3 (en) G-protein coupled receptors and uses therefor
AU2894289A (en) Domain-modified constant region antibodies
IL175698A0 (en) Phosphodiesterase 8a
NZ512083A (en) Methods of increasing lean tissue mass using OB protein compositions
HK1112018A1 (en) Human toll-like receptor proteins, related reagents and methods
HU9600692D0 (en) Human metabotropic glutamate receptor subtypes (hmr4, hmr6, hmr7) and related dna compounds
EP1364969A3 (en) Human tissue factor related DNA segments, polypeptides and antibodies
WO1995019435A3 (en) T cell antigen receptor v region proteins and methods of preparation thereof
WO1996007738A3 (en) Modified human c3 proteins
CA2173102A1 (en) Dna sequence coding for a bmp receptor
AU4375493A (en) Isolated protein receptors, antibodies which bind thereto, nucleic acid sequence coding therefor, and uses thereof
WO1999009182A3 (en) Rab proteins
DK0868511T3 (da) Genekspression af utrophin
EP2301947A3 (en) Secreted proteins and uses thereof
WO1999000408A3 (en) Human transmembrane protein from the transmembrane 4 superfamily
WO2001090365A3 (en) Human protein kinase '13305' and uses therefor
WO2001096400A3 (en) 52871, a novel human g protein coupled receptor and uses thereof
WO2001014414A3 (en) Human abc2 transporter and uses thereof
ZA91699B (en) Antibodies specifically recognizing somatotropin binding protein
WO2002044357A3 (en) Methods of using 18903 to treat pain and pain-related disorders
WO2003087331A3 (en) Polyvalent cation-sensing receptor in atlantic salmon
WO2003027316A3 (en) Methods of using 33751, a human potassium channel family member
WO2001042294A3 (en) Clasp-4 transmembrane protein
WO2003030616A3 (en) 21132, a human g-protein coupled receptor family member and uses therefor