DE69233191D1 - Cyclin d1 und seine cdna - Google Patents

Cyclin d1 und seine cdna

Info

Publication number
DE69233191D1
DE69233191D1 DE69233191T DE69233191T DE69233191D1 DE 69233191 D1 DE69233191 D1 DE 69233191D1 DE 69233191 T DE69233191 T DE 69233191T DE 69233191 T DE69233191 T DE 69233191T DE 69233191 D1 DE69233191 D1 DE 69233191D1
Authority
DE
Germany
Prior art keywords
prad1
disclosed
antibodies
nucleic acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69233191T
Other languages
English (en)
Other versions
DE69233191T2 (de
Inventor
Andrew Arnold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24679321&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69233191(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE69233191D1 publication Critical patent/DE69233191D1/de
Publication of DE69233191T2 publication Critical patent/DE69233191T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/15Humanized animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0331Animal model for proliferative diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69233191T 1991-03-11 1992-03-11 Cyclin Prad1 (Cyclin D1) und seine cDNA Expired - Fee Related DE69233191T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/667,711 US6110700A (en) 1991-03-11 1991-03-11 PRAD1 cyclin and its cDNA
US667711 1991-03-11
PCT/US1992/001925 WO1992015603A1 (en) 1991-03-11 1992-03-11 Prad1 cyclin and its cdna

Publications (2)

Publication Number Publication Date
DE69233191D1 true DE69233191D1 (de) 2003-10-16
DE69233191T2 DE69233191T2 (de) 2004-06-17

Family

ID=24679321

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233191T Expired - Fee Related DE69233191T2 (de) 1991-03-11 1992-03-11 Cyclin Prad1 (Cyclin D1) und seine cDNA

Country Status (8)

Country Link
US (3) US6110700A (de)
EP (1) EP0575546B1 (de)
JP (1) JP3369169B2 (de)
AT (1) ATE249476T1 (de)
CA (1) CA2104871C (de)
DE (1) DE69233191T2 (de)
DK (1) DK0575546T3 (de)
WO (1) WO1992015603A1 (de)

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US7550561B1 (en) * 1991-05-16 2009-06-23 Cold Spring Harbor Laboratory p16INK4 polypeptides
US6156876A (en) * 1991-05-16 2000-12-05 Cold Spring Harbor Laboratory D-type cyclin and uses related thereto
US5543291A (en) * 1993-01-29 1996-08-06 Dana Farber Cancer Institute Method of detecting carcinoma
US5514571A (en) * 1993-08-05 1996-05-07 University Technologies International Inc. Cyclin D1 negative regulatory activity
US20020073441A1 (en) 2000-12-13 2002-06-13 Ross Brian D. Compositions and methods for detecting proteolytic activity
EP1497418B1 (de) 2002-04-19 2012-10-17 Verenium Corporation Phospholipasen, diese codierende nukleinsäuren sowie verfahren zu ihrer herstellung und verwendung
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CA2889013C (en) 2003-03-07 2018-07-17 Dsm Ip Assets B.V. Hydrolases, nucleic acids encoding them and methods for making and using them
GB0307428D0 (en) * 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307403D0 (en) * 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US7592434B2 (en) 2003-04-04 2009-09-22 Verenium Corporation Pectate lyases, nucleic encoding them and methods for making and using them
BRPI0412279A (pt) 2003-07-02 2006-09-19 Diversa Corp glucanases, ácidos nucléicos codificando as mesmas e métodos para preparar e aplicar os mesmos
CA2535526C (en) 2003-08-11 2015-09-29 Diversa Corporation Laccases, nucleic acids encoding them and methods for making and using them
US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
CN103173282A (zh) 2004-06-16 2013-06-26 帝斯曼知识产权资产管理有限公司 对叶绿素进行酶促脱色的组合物和方法
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
CA2614769A1 (en) 2005-03-10 2006-09-21 Verenium Corporation Lyase enzymes, nucleic acids encoding them and methods for making and using them
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US20100137163A1 (en) 2006-01-11 2010-06-03 Link Darren R Microfluidic Devices and Methods of Use in The Formation and Control of Nanoreactors
WO2007092314A2 (en) 2006-02-02 2007-08-16 Verenium Corporation Esterases and related nucleic acids and methods
DK2444487T3 (en) 2006-02-10 2018-05-28 Bp Corp North America Inc CELLULOLYTIC ENZYMES, NUCLEIC ACIDS, CODING THEM, AND PROCEDURES FOR THEIR PREPARATION AND USE
EP3406621A1 (de) 2006-02-14 2018-11-28 BP Corporation North America Inc. Xylanasen, dafür codierende nukleinsäuren sowie verfahren zur herstellung und verwendung davon
EA029538B1 (ru) 2006-03-07 2018-04-30 Басф Энзаймс Ллк Полипептид, обладающий активностью альдолазы, полинуклеотид, кодирующий этот полипептид, и способы получения и применения полинуклеотида и полипептида
BRPI0708673A2 (pt) 2006-03-07 2011-06-07 Cargill Inc método para fabricação de polipeptìdeos com atividade de aldolase e polinucleotìdeos que codificam estes polipeptìdeos
WO2007133710A2 (en) 2006-05-11 2007-11-22 Raindance Technologies, Inc. Microfluidic devices and methods of use thereof
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
AU2007356171B8 (en) 2006-08-04 2014-01-16 Bp Corporation North America Inc. Glucanases, nucleic acids encoding them, and methods for making and using them
WO2008021123A1 (en) 2006-08-07 2008-02-21 President And Fellows Of Harvard College Fluorocarbon emulsion stabilizing surfactants
WO2008036863A2 (en) 2006-09-21 2008-03-27 Verenium Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
PL2617823T3 (pl) 2006-09-21 2015-12-31 Basf Enzymes Llc Fitazy, kodujące je kwasy nukleinowe oraz sposoby ich wytwarzania i stosowania
CA2982640A1 (en) 2006-12-21 2008-07-03 Basf Enzymes Llc Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
US8772046B2 (en) * 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
CN103757036B (zh) 2007-10-03 2019-10-01 维莱尼姆公司 木聚糖酶、编码它们的核酸以及其制备和应用方法
WO2009058881A1 (en) * 2007-10-29 2009-05-07 The University Of California Osteoarthritis gene therapy
US8541220B2 (en) 2008-01-03 2013-09-24 Verenium Corporation Isomerases, nucleic acids encoding them and methods for making and using them
PL2238242T3 (pl) 2008-01-03 2015-06-30 Basf Enzymes Llc Transferazy i oksydoreduktazy, kwasy nukleinowe kodujące je oraz sposoby ich wytwarzania i zastosowania
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* Cited by examiner, † Cited by third party
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US4535058A (en) * 1982-10-01 1985-08-13 Massachusetts Institute Of Technology Characterization of oncogenes and assays based thereon
NZ212291A (en) * 1984-06-08 1991-10-25 Suntory Ltd Peptide from human atrium cordis having diuretic action, dna coding therefor and pharmaceutical compositions thereof
US6110700A (en) * 1991-03-11 2000-08-29 The General Hospital Corporation PRAD1 cyclin and its cDNA
US5538846A (en) * 1992-09-17 1996-07-23 Meeker; Timothy C. BCL-1 locus nucleic acid probes and assay methods

Also Published As

Publication number Publication date
CA2104871C (en) 2009-12-22
EP0575546A1 (de) 1993-12-29
JPH06505398A (ja) 1994-06-23
JP3369169B2 (ja) 2003-01-20
DK0575546T3 (da) 2004-01-26
EP0575546A4 (en) 1996-04-03
US6107541A (en) 2000-08-22
US5858655A (en) 1999-01-12
US6110700A (en) 2000-08-29
CA2104871A1 (en) 1992-09-12
ATE249476T1 (de) 2003-09-15
WO1992015603A1 (en) 1992-09-17
DE69233191T2 (de) 2004-06-17
EP0575546B1 (de) 2003-09-10

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