ATE399757T1 - Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol - Google Patents

Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol

Info

Publication number
ATE399757T1
ATE399757T1 AT04798162T AT04798162T ATE399757T1 AT E399757 T1 ATE399757 T1 AT E399757T1 AT 04798162 T AT04798162 T AT 04798162T AT 04798162 T AT04798162 T AT 04798162T AT E399757 T1 ATE399757 T1 AT E399757T1
Authority
AT
Austria
Prior art keywords
paracetamol
producing
new process
nitrooxy derivatives
nitrooxy
Prior art date
Application number
AT04798162T
Other languages
German (de)
English (en)
Inventor
Romano Rivolta
Roberto Aureli
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Application granted granted Critical
Publication of ATE399757T1 publication Critical patent/ATE399757T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04798162T 2003-11-20 2004-11-04 Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol ATE399757T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03292892 2003-11-20

Publications (1)

Publication Number Publication Date
ATE399757T1 true ATE399757T1 (de) 2008-07-15

Family

ID=34639350

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04798162T ATE399757T1 (de) 2003-11-20 2004-11-04 Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol

Country Status (8)

Country Link
US (1) US7442826B2 (enExample)
EP (1) EP1727787B1 (enExample)
JP (1) JP2007511581A (enExample)
AT (1) ATE399757T1 (enExample)
CA (1) CA2546807A1 (enExample)
DE (1) DE602004014822D1 (enExample)
ES (1) ES2309579T3 (enExample)
WO (1) WO2005054175A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2574666A1 (en) * 2004-07-20 2006-01-26 Nicox S.A. Process for preparing nitrooxy esters, nitrooxy thioesters, nitrooxy carbonates and nitrooxy thiocarbonates, intermediates useful in said process and preparation thereof
ES2441263T3 (es) 2007-08-17 2014-02-03 Council Of Scientific & Industrial Research Derivados de paracetamol que liberan óxido nítrico
US8062653B2 (en) * 2009-02-18 2011-11-22 Bezwada Biomedical, Llc Controlled release of nitric oxide and drugs from functionalized macromers and oligomers
WO2010108843A1 (en) * 2009-03-27 2010-09-30 Nicox S.A. Use of nitrooxyderivative of paracetamol for the treatment of muscular dystrophies
KR101794363B1 (ko) * 2009-12-11 2017-11-06 디에스엠 아이피 어셋츠 비.브이. 반추동물에서의 메탄 방출을 감소시키고/감소시키거나 반추동물 수익성을 개선시키기 위한 사료중의 니트로옥시 알칸산 및 이의 유도체
US10154981B2 (en) 2011-05-26 2018-12-18 Dsm Ip Assets B.V. Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3443998A1 (de) 1984-12-01 1986-06-05 Boehringer Mannheim Gmbh, 6800 Mannheim Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
IT1307928B1 (it) * 1999-01-26 2001-11-29 Nicox Sa Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina.
IT1314184B1 (it) * 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo
IT1319202B1 (it) 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
US20030219494A1 (en) * 2002-03-20 2003-11-27 Smith Maree Therese Compositions and methods of using them
ITMI20020597A1 (it) * 2002-03-22 2003-09-22 Nicox Sa Derivati del probucolo

Also Published As

Publication number Publication date
EP1727787A2 (en) 2006-12-06
WO2005054175A3 (en) 2006-11-30
EP1727787B1 (en) 2008-07-02
WO2005054175A2 (en) 2005-06-16
DE602004014822D1 (de) 2008-08-14
JP2007511581A (ja) 2007-05-10
ES2309579T3 (es) 2008-12-16
CA2546807A1 (en) 2005-06-16
US20070149801A1 (en) 2007-06-28
US7442826B2 (en) 2008-10-28

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Legal Events

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