DE602004014822D1 - Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol - Google Patents
Neues verfahren zur herstellung von nitrooxyderivaten von paracetamolInfo
- Publication number
- DE602004014822D1 DE602004014822D1 DE602004014822T DE602004014822T DE602004014822D1 DE 602004014822 D1 DE602004014822 D1 DE 602004014822D1 DE 602004014822 T DE602004014822 T DE 602004014822T DE 602004014822 T DE602004014822 T DE 602004014822T DE 602004014822 D1 DE602004014822 D1 DE 602004014822D1
- Authority
- DE
- Germany
- Prior art keywords
- paracetamol
- production
- new method
- nitrooxy derivatives
- nitrooxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- -1 NITROOXY DERIVATIVES OF PARACETAMOL Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03292892 | 2003-11-20 | ||
| PCT/EP2004/052806 WO2005054175A2 (en) | 2003-11-20 | 2004-11-04 | New process for the preparation of nitrooxyderivatives of paracetamol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004014822D1 true DE602004014822D1 (de) | 2008-08-14 |
Family
ID=34639350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004014822T Expired - Lifetime DE602004014822D1 (de) | 2003-11-20 | 2004-11-04 | Neues verfahren zur herstellung von nitrooxyderivaten von paracetamol |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7442826B2 (enExample) |
| EP (1) | EP1727787B1 (enExample) |
| JP (1) | JP2007511581A (enExample) |
| AT (1) | ATE399757T1 (enExample) |
| CA (1) | CA2546807A1 (enExample) |
| DE (1) | DE602004014822D1 (enExample) |
| ES (1) | ES2309579T3 (enExample) |
| WO (1) | WO2005054175A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2574666A1 (en) * | 2004-07-20 | 2006-01-26 | Nicox S.A. | Process for preparing nitrooxy esters, nitrooxy thioesters, nitrooxy carbonates and nitrooxy thiocarbonates, intermediates useful in said process and preparation thereof |
| ES2441263T3 (es) | 2007-08-17 | 2014-02-03 | Council Of Scientific & Industrial Research | Derivados de paracetamol que liberan óxido nítrico |
| US8062653B2 (en) * | 2009-02-18 | 2011-11-22 | Bezwada Biomedical, Llc | Controlled release of nitric oxide and drugs from functionalized macromers and oligomers |
| WO2010108843A1 (en) * | 2009-03-27 | 2010-09-30 | Nicox S.A. | Use of nitrooxyderivative of paracetamol for the treatment of muscular dystrophies |
| KR101794363B1 (ko) * | 2009-12-11 | 2017-11-06 | 디에스엠 아이피 어셋츠 비.브이. | 반추동물에서의 메탄 방출을 감소시키고/감소시키거나 반추동물 수익성을 개선시키기 위한 사료중의 니트로옥시 알칸산 및 이의 유도체 |
| US10154981B2 (en) | 2011-05-26 | 2018-12-18 | Dsm Ip Assets B.V. | Use of a feed composition for reducing methane emission in ruminants, and/or to improve ruminant performance |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3443998A1 (de) | 1984-12-01 | 1986-06-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| IT1307928B1 (it) * | 1999-01-26 | 2001-11-29 | Nicox Sa | Metodo di sintesi di nitrossimetilfenil esteri di derivatidell'aspirina. |
| IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
| IT1319202B1 (it) | 2000-10-12 | 2003-09-26 | Nicox Sa | Farmaci per le malattie a base infiammatoria. |
| US20030219494A1 (en) * | 2002-03-20 | 2003-11-27 | Smith Maree Therese | Compositions and methods of using them |
| ITMI20020597A1 (it) * | 2002-03-22 | 2003-09-22 | Nicox Sa | Derivati del probucolo |
-
2004
- 2004-11-04 US US10/579,904 patent/US7442826B2/en not_active Expired - Fee Related
- 2004-11-04 CA CA002546807A patent/CA2546807A1/en not_active Abandoned
- 2004-11-04 EP EP04798162A patent/EP1727787B1/en not_active Expired - Lifetime
- 2004-11-04 WO PCT/EP2004/052806 patent/WO2005054175A2/en not_active Ceased
- 2004-11-04 JP JP2006540430A patent/JP2007511581A/ja active Pending
- 2004-11-04 ES ES04798162T patent/ES2309579T3/es not_active Expired - Lifetime
- 2004-11-04 AT AT04798162T patent/ATE399757T1/de not_active IP Right Cessation
- 2004-11-04 DE DE602004014822T patent/DE602004014822D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1727787A2 (en) | 2006-12-06 |
| WO2005054175A3 (en) | 2006-11-30 |
| EP1727787B1 (en) | 2008-07-02 |
| WO2005054175A2 (en) | 2005-06-16 |
| JP2007511581A (ja) | 2007-05-10 |
| ES2309579T3 (es) | 2008-12-16 |
| ATE399757T1 (de) | 2008-07-15 |
| CA2546807A1 (en) | 2005-06-16 |
| US20070149801A1 (en) | 2007-06-28 |
| US7442826B2 (en) | 2008-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |