ATE393784T1 - Mittel zur bestimmung und reinigung von lymphocytenpopulationen des typs tcd8+, die spezifisch für im zusammenhang mit hla präsentierte peptide sind - Google Patents
Mittel zur bestimmung und reinigung von lymphocytenpopulationen des typs tcd8+, die spezifisch für im zusammenhang mit hla präsentierte peptide sindInfo
- Publication number
- ATE393784T1 ATE393784T1 AT00960796T AT00960796T ATE393784T1 AT E393784 T1 ATE393784 T1 AT E393784T1 AT 00960796 T AT00960796 T AT 00960796T AT 00960796 T AT00960796 T AT 00960796T AT E393784 T1 ATE393784 T1 AT E393784T1
- Authority
- AT
- Austria
- Prior art keywords
- tcd8
- hla
- purifying
- agent
- determining
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 210000004698 lymphocyte Anatomy 0.000 title 1
- 230000003993 interaction Effects 0.000 abstract 2
- 102000043129 MHC class I family Human genes 0.000 abstract 1
- 108091054437 MHC class I family Proteins 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9911133A FR2798128B1 (fr) | 1999-09-06 | 1999-09-06 | Moyens de detection et de purification de populations lymphocytaires t cd8+ specifiques de peptides presentes dans le contexte hla |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE393784T1 true ATE393784T1 (de) | 2008-05-15 |
Family
ID=9549571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00960796T ATE393784T1 (de) | 1999-09-06 | 2000-09-05 | Mittel zur bestimmung und reinigung von lymphocytenpopulationen des typs tcd8+, die spezifisch für im zusammenhang mit hla präsentierte peptide sind |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1127072B1 (de) |
| JP (1) | JP5020452B2 (de) |
| CN (2) | CN101298478B (de) |
| AT (1) | ATE393784T1 (de) |
| AU (1) | AU778840B2 (de) |
| CA (1) | CA2350185C (de) |
| DE (2) | DE1127072T1 (de) |
| FR (1) | FR2798128B1 (de) |
| IL (1) | IL142976A0 (de) |
| WO (1) | WO2001018053A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9923337D0 (en) * | 1999-10-04 | 1999-12-08 | Isis Innovation | Binding agents |
| DE10117858A1 (de) * | 2001-04-10 | 2002-10-24 | Gsf Forschungszentrum Umwelt | MHC-Tetramere |
| NZ591133A (en) | 2008-09-02 | 2012-08-31 | Inst Nat Sante Rech Med | Novel melanoma antigen peptide and uses thereof |
| ES2635335T3 (es) * | 2010-09-20 | 2017-10-03 | Biontech Cell & Gene Therapies Gmbh | Receptores de células T específicos de antígeno y epítopos de células T |
| WO2012164004A1 (en) | 2011-06-01 | 2012-12-06 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel antigen peptide and uses thereof |
| WO2013175258A1 (en) | 2012-05-22 | 2013-11-28 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Novel melanoma antigen peptide and uses thereof |
| WO2015150491A1 (en) | 2014-04-01 | 2015-10-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | An isolated donor mhc-derived peptide and uses thereof |
| US10137181B2 (en) | 2014-04-01 | 2018-11-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Isolated donor MHC-derived peptide and uses thereof |
| US20210023209A1 (en) | 2018-03-16 | 2021-01-28 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigenic peptides deriving from pcsk2 and uses thereof for the diagnosis and treatment of type 1 diabetes |
| EP3765053A2 (de) | 2018-03-16 | 2021-01-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigene peptide aus urocortin 3 und verwendungen davon zur diagnose und behandlung von typ-1-diabetes |
| WO2019175380A2 (en) | 2018-03-16 | 2019-09-19 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antigenic peptides deriving from secretogranin v and uses thereof for the diagnosis and treatment of type 1 diabetes |
| ES2935702T3 (es) | 2018-04-11 | 2023-03-09 | Enterome S A | Péptidos antigénicos para la prevención y el tratamiento del cáncer |
| CN109293779A (zh) * | 2018-07-03 | 2019-02-01 | 清华大学 | 一种多聚体复合物及其制备方法 |
| EP3894543A1 (de) | 2018-12-14 | 2021-10-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Isolierte humane mhc-abgeleitete peptide und verwendungen davon zur stimulierung und aktivierung der suppressiven funktion von cd8cd45rc + cd45rc low tregs |
| WO2020148206A1 (en) | 2019-01-14 | 2020-07-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for generating and selecting a variant of a binding protein with increased binding affinity and/or specificity |
| PL4021487T3 (pl) | 2019-11-15 | 2024-04-15 | Enterome S.A. | Peptydy antygenowe do zapobiegania i leczenia nowotworów złośliwych wywodzących się z limfocytów b |
| WO2023115459A1 (zh) * | 2021-12-23 | 2023-06-29 | 青岛华赛伯曼医学细胞生物有限公司 | 一种肿瘤抗原/mhc-i复合物及其制备方法和用途 |
| AU2023246941A1 (en) | 2022-03-31 | 2024-10-24 | Enterome S.A. | Antigenic peptides for prevention and treatment of cancer. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635363A (en) * | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
| WO1997044667A2 (fr) * | 1996-05-21 | 1997-11-27 | Institut Pasteur | Methodes d'utilisation de complexes peptide/complexe majeur d'histocompatibilite pour obtenir ou purifier des cellules t antigene-specifiques et pour stimuler des cellules t |
| US6248564B1 (en) * | 1997-08-29 | 2001-06-19 | Harvard University | Mutant MHC class I molecules |
-
1999
- 1999-09-06 FR FR9911133A patent/FR2798128B1/fr not_active Expired - Lifetime
-
2000
- 2000-09-05 IL IL14297600A patent/IL142976A0/xx unknown
- 2000-09-05 EP EP00960796A patent/EP1127072B1/de not_active Expired - Lifetime
- 2000-09-05 WO PCT/FR2000/002443 patent/WO2001018053A1/fr not_active Ceased
- 2000-09-05 DE DE1127072T patent/DE1127072T1/de active Pending
- 2000-09-05 CN CN2008100872673A patent/CN101298478B/zh not_active Expired - Lifetime
- 2000-09-05 DE DE60038726T patent/DE60038726T2/de not_active Expired - Lifetime
- 2000-09-05 AT AT00960796T patent/ATE393784T1/de not_active IP Right Cessation
- 2000-09-05 CN CN00801877A patent/CN1321167A/zh active Pending
- 2000-09-05 JP JP2001522275A patent/JP5020452B2/ja not_active Expired - Lifetime
- 2000-09-05 AU AU72981/00A patent/AU778840B2/en not_active Expired
- 2000-09-05 CA CA2350185A patent/CA2350185C/fr not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2798128A1 (fr) | 2001-03-09 |
| DE60038726T2 (de) | 2009-07-02 |
| EP1127072A1 (de) | 2001-08-29 |
| CA2350185A1 (fr) | 2001-03-15 |
| DE60038726D1 (de) | 2008-06-12 |
| CN1321167A (zh) | 2001-11-07 |
| AU7298100A (en) | 2001-04-10 |
| EP1127072B1 (de) | 2008-04-30 |
| CN101298478A (zh) | 2008-11-05 |
| DE1127072T1 (de) | 2002-05-23 |
| CA2350185C (fr) | 2012-02-21 |
| IL142976A0 (en) | 2002-04-21 |
| JP5020452B2 (ja) | 2012-09-05 |
| AU778840B2 (en) | 2004-12-23 |
| CN101298478B (zh) | 2013-01-02 |
| FR2798128B1 (fr) | 2001-11-16 |
| WO2001018053A1 (fr) | 2001-03-15 |
| JP2003510039A (ja) | 2003-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |