DE69840868D1 - Mage-3 peptide, die durch hla-klasse-ii molecule presentiert werden - Google Patents

Mage-3 peptide, die durch hla-klasse-ii molecule presentiert werden

Info

Publication number
DE69840868D1
DE69840868D1 DE69840868T DE69840868T DE69840868D1 DE 69840868 D1 DE69840868 D1 DE 69840868D1 DE 69840868 T DE69840868 T DE 69840868T DE 69840868 T DE69840868 T DE 69840868T DE 69840868 D1 DE69840868 D1 DE 69840868D1
Authority
DE
Germany
Prior art keywords
mage
hla class
molecule
peptides
peptides presented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840868T
Other languages
English (en)
Inventor
Kris Thielemans
Carlo Heirman
Jurgen Corthals
Pascal Chaux
Vincent Stroobant
Thierry Boon-Falleur
Der Bruggen Pierre Van
Rosalie Luiten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vrije Universiteit Brussel VUB
Universite Libre de Bruxelles ULB
Ludwig Institute for Cancer Research Ltd
Ludwig Institute for Cancer Research New York
Original Assignee
Vrije Universiteit Brussel VUB
Universite Libre de Bruxelles ULB
Ludwig Institute for Cancer Research Ltd
Ludwig Institute for Cancer Research New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vrije Universiteit Brussel VUB, Universite Libre de Bruxelles ULB, Ludwig Institute for Cancer Research Ltd, Ludwig Institute for Cancer Research New York filed Critical Vrije Universiteit Brussel VUB
Application granted granted Critical
Publication of DE69840868D1 publication Critical patent/DE69840868D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69840868T 1997-09-12 1998-09-04 Mage-3 peptide, die durch hla-klasse-ii molecule presentiert werden Expired - Lifetime DE69840868D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/928,615 US5965535A (en) 1997-09-12 1997-09-12 Mage-3 peptides presented by HLA class II molecules
PCT/US1998/018601 WO1999014326A1 (en) 1997-09-12 1998-09-04 Mage-3 peptides presented by hla class ii molecules

Publications (1)

Publication Number Publication Date
DE69840868D1 true DE69840868D1 (de) 2009-07-16

Family

ID=25456537

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840868T Expired - Lifetime DE69840868D1 (de) 1997-09-12 1998-09-04 Mage-3 peptide, die durch hla-klasse-ii molecule presentiert werden

Country Status (9)

Country Link
US (2) US5965535A (de)
EP (1) EP1012283B1 (de)
JP (1) JP4106179B2 (de)
AT (1) ATE432983T1 (de)
AU (1) AU757368B2 (de)
CA (1) CA2303063C (de)
DE (1) DE69840868D1 (de)
WO (1) WO1999014326A1 (de)
ZA (1) ZA988124B (de)

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ES2224113T5 (es) * 1994-02-16 2009-05-01 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Polipeptido antigenico asociado al melanoma, epitopos del mismo y vacunas contra melanoma.
US20040156861A1 (en) 1996-07-11 2004-08-12 Figdor Carl Gustav Melanoma associated peptide analogues and vaccines against melanoma
US6716809B1 (en) 1997-09-12 2004-04-06 Ludwig Institute For Cancer Research Mage-A3 peptides presented by HLA class molecules
US6291430B1 (en) 1997-09-12 2001-09-18 Ludwig Institute For Cancer Research Mage-3 peptides presented by HLA class II molecules
WO1999040188A2 (en) 1998-02-05 1999-08-12 Smithkline Beecham Biologicals S.A. Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccinations
US6800730B1 (en) * 1998-10-02 2004-10-05 Ludwig Institute For Cancer Research Isolated peptides which bind to MHC class II molecules, and uses thereof
US6710172B1 (en) 1998-10-02 2004-03-23 Ludwig Institute For Cancer Research Tumor antigens and CTL clones isolated by a novel procedure
US6407063B1 (en) 1998-10-02 2002-06-18 Ludwig Institute For Cancer Research Tumor antigens and CTL clones isolated by a novel procedure
IT1309584B1 (it) * 1999-02-26 2002-01-24 San Raffaele Centro Fond Peptidi immunogenici derivati da mage-3 presentati da mhc di classeii e loro uso.
IT1312568B1 (it) * 1999-05-21 2002-04-22 Genera Spa Peptidi immunogenici e loro uso.
US7157091B1 (en) * 1999-06-18 2007-01-02 Ludwig Institute For Cancer Research MAGE-A1 peptides presented by HLA class II molecules
US7429639B2 (en) * 1999-09-29 2008-09-30 Ludwig Institute For Cancer Research SSX-2 peptides presented by HLA class II molecules
JP2003512057A (ja) * 1999-10-19 2003-04-02 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ Ｍａｇｅ−ａ１２抗原ペプチド及びその利用
US6897288B1 (en) 1999-10-19 2005-05-24 Ludwig Institute For Cancer Research Mage-A12 antigenic peptides and uses thereof
US6605711B1 (en) * 1999-11-15 2003-08-12 Ludwig Institute For Cancer Research NY-ESO-1 peptide derivatives, and uses thereof
CA2393339A1 (en) * 1999-12-10 2001-06-14 Epimmune Inc. Inducing cellular immune responses to mage2/3 using peptide and nucleic acid compositions
US7851212B2 (en) * 2000-05-10 2010-12-14 Sanofi Pasteur Limited Immunogenic polypeptides encoded by MAGE minigenes and uses thereof
US7803382B2 (en) 2001-05-04 2010-09-28 Ludwig Institute For Cancer Research Ltd. Method for inducing immune response to NY-CO-58
US6794501B2 (en) * 2001-05-04 2004-09-21 Ludwig Institute For Cancer Research Colon cancer antigen panel
AU2002322009A1 (en) * 2001-05-18 2002-12-03 Mayo Foundation For Medical Education And Research Chimeric antigen-specific t cell-activating polypeptides
US7049413B2 (en) * 2001-05-18 2006-05-23 Ludwig Institute For Cancer Research MAGE-A3 peptides presented by HLA class II molecules
US20060222656A1 (en) * 2005-04-01 2006-10-05 University Of Maryland, Baltimore MAGE-A3/HPV 16 peptide vaccines for head and neck cancer
EP2284535A1 (de) 2002-03-11 2011-02-16 Momenta Pharmaceuticals, Inc. Heparine mit niedrigem Molekulargewicht
WO2005035773A2 (en) * 2003-10-08 2005-04-21 Sanofi Pasteur, Inc. Modified cea /b7 vector
CN1658899B (zh) 2002-04-09 2013-01-02 安万特巴斯德有限公司 经修饰的cea核酸及表达载体
US20040223949A1 (en) * 2002-10-22 2004-11-11 Sunnybrook And Women's College Health Sciences Center Aventis Pasteur, Ltd. Vaccines using high-dose cytokines
CN1708320A (zh) * 2002-11-07 2005-12-14 郎基·常 经修饰的树突状细胞
US20070154889A1 (en) * 2004-06-25 2007-07-05 Veridex, Llc Methods and reagents for the detection of melanoma
US7858743B2 (en) * 2004-09-09 2010-12-28 Ludwig Institute For Cancer Research SSX-4 peptides presented by HLA class II molecules
WO2006045750A2 (en) * 2004-10-20 2006-05-04 Friedrich-Alexander- Universität Erlangen- Nürnberg T-cell stimulatory peptides from the melanoma-associated chondroitin sulfate proteoglycan and their use
WO2008053573A1 (fr) 2006-10-30 2008-05-08 National University Corporation Hokkaido University Remède pour néoplasme malin
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
US9045729B2 (en) 2009-12-10 2015-06-02 Ottawa Hospital Research Institute Oncolytic rhabdovirus
CN102791742B (zh) 2010-01-19 2014-12-24 动量制药公司 评价肝素制剂
US9068957B2 (en) 2011-02-21 2015-06-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
CN105658790A (zh) * 2013-02-21 2016-06-08 东安大略研究所儿童医院有限公司 疫苗组合物
CA2953747A1 (en) * 2013-06-28 2014-12-31 Auckland Uniservices Limited Amino acid and peptide conjugates and conjugation process
US9976146B2 (en) * 2014-05-30 2018-05-22 Academia Sinica Aptamer targeting MAGE-A3 peptide and uses thereof
WO2016103192A1 (en) 2014-12-23 2016-06-30 Margaret Anne Brimble Amino acid and peptide conjugates and uses thereof
EA201891639A1 (ru) 2016-02-26 2019-06-28 Окленд Юнисервисес Лимитед Аминокислотные и пептидные конъюгаты и способ конъюгации
US10441509B2 (en) * 2018-03-16 2019-10-15 Berkshire Biomedical, LLC Computerized oral prescription administration with refillable medication dispensing devices and associated systems and methods

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GB9019409D0 (en) * 1990-09-05 1990-10-17 Pfizer Ltd Therapeutic agents
US5139325A (en) * 1991-01-25 1992-08-18 Oksman Henry C Wide depth of focus power add to intraocular and contact lenses
US6235525B1 (en) 1991-05-23 2001-05-22 Ludwig Institute For Cancer Research Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof
US5342774A (en) 1991-05-23 1994-08-30 Ludwig Institute For Cancer Research Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1
US5348578A (en) * 1991-10-23 1994-09-20 Ppg Industries (France) S.A. Products obtained from the reaction of amine-diol and a polyfunctional substance and application of such products to electroapplicable cationic paint compositions
US5662907A (en) * 1992-08-07 1997-09-02 Cytel Corporation Induction of anti-tumor cytotoxic T lymphocytes in humans using synthetic peptide epitopes
ATE280180T1 (de) * 1992-08-31 2004-11-15 Ludwig Inst Cancer Res Vom mage-3-gen abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen
US5405940A (en) * 1992-08-31 1995-04-11 Ludwig Institute For Cancer Research Isolated nonapeptides derived from MAGE genes and uses thereof
US5364838A (en) 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
US5414610A (en) * 1993-06-21 1995-05-09 Ast Research, Inc. Universal power converter with single, shared power transformation circuit
US5696764A (en) * 1993-07-21 1997-12-09 Fujitsu Limited ATM exchange for monitoring congestion and allocating and transmitting bandwidth-guaranteed and non-bandwidth-guaranteed connection calls
US5851523A (en) 1994-03-24 1998-12-22 Ludwig Institute For Cancer Research. Isolated, peptides derived from MAGE tumor rejection antigen precursors which complex with HLA-A2 molecules and uses thereof
US5585461A (en) * 1994-03-24 1996-12-17 Ludwig Institute For Cancer Research Isolated, MAGE-3 derived peptides which complex with HLA-A2 molecules and uses thereof
EP0801192B1 (de) * 1994-11-11 2005-01-26 Kabushiki Kaisha Tokai Rika Denki Seisakusho Verfahren zum registrieren eines identifikationskodes
DE4441903C1 (de) * 1994-11-24 1996-03-21 Siemens Ag Drucksensor
US6951917B1 (en) 1995-09-26 2005-10-04 The United States Of America As Represented By The Department Of Health And Human Services MHC-class II restricted melanoma antigens and their use in therapeutic methods
WO1997013858A2 (en) * 1995-10-12 1997-04-17 Chiron Corporation Baboon mage-3 homologs, dna encoding the homologs, and a process for their use
EP2724617A1 (de) 2012-10-25 2014-04-30 Commissariat A L'energie Atomique Et Aux Energies Alternatives Verbindungen zum Abschwächen von Phosphatsterbesymptomen bei Pflanzen
US9603182B2 (en) 2013-03-14 2017-03-21 Qualcomm Incorporated Establishing reliable always-on packet data network connections

Also Published As

Publication number Publication date
JP2001516579A (ja) 2001-10-02
ATE432983T1 (de) 2009-06-15
EP1012283A1 (de) 2000-06-28
US6369211B1 (en) 2002-04-09
CA2303063A1 (en) 1999-03-25
AU9306198A (en) 1999-04-05
AU757368B2 (en) 2003-02-20
CA2303063C (en) 2009-11-24
EP1012283B1 (de) 2009-06-03
ZA988124B (en) 1999-03-05
WO1999014326A1 (en) 1999-03-25
US5965535A (en) 1999-10-12
JP4106179B2 (ja) 2008-06-25

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