ATE391707T1 - Verfahren zur synthese von aminen wie ephedrin und zwischenprodukten - Google Patents

Verfahren zur synthese von aminen wie ephedrin und zwischenprodukten

Info

Publication number
ATE391707T1
ATE391707T1 AT02764370T AT02764370T ATE391707T1 AT E391707 T1 ATE391707 T1 AT E391707T1 AT 02764370 T AT02764370 T AT 02764370T AT 02764370 T AT02764370 T AT 02764370T AT E391707 T1 ATE391707 T1 AT E391707T1
Authority
AT
Austria
Prior art keywords
sub
optionally substituted
alkyl
formula
ephedrine
Prior art date
Application number
AT02764370T
Other languages
English (en)
Inventor
Andrew Smallridge
Maurice Trewhella
Kylie Wilkinson
Original Assignee
Victoria University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Victoria University filed Critical Victoria University
Application granted granted Critical
Publication of ATE391707T1 publication Critical patent/ATE391707T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/24Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds
    • C07C209/26Preparation of compounds containing amino groups bound to a carbon skeleton by reductive alkylation of ammonia, amines or compounds having groups reducible to amino groups, with carbonyl compounds by reduction with hydrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/02Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/54Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02764370T 2001-08-28 2002-08-26 Verfahren zur synthese von aminen wie ephedrin und zwischenprodukten ATE391707T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPR7326A AUPR732601A0 (en) 2001-08-28 2001-08-28 Methods for the synthesis of amines such as ephedrine and inter mediates

Publications (1)

Publication Number Publication Date
ATE391707T1 true ATE391707T1 (de) 2008-04-15

Family

ID=3831278

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02764370T ATE391707T1 (de) 2001-08-28 2002-08-26 Verfahren zur synthese von aminen wie ephedrin und zwischenprodukten

Country Status (7)

Country Link
US (1) US7176332B2 (de)
EP (1) EP1421055B1 (de)
JP (1) JP2005500399A (de)
AT (1) ATE391707T1 (de)
AU (2) AUPR732601A0 (de)
DE (1) DE60226038T2 (de)
WO (1) WO2003018531A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0406125D0 (en) 2004-03-18 2004-04-21 Univ Cambridge Tech Methods of amination
US7414153B2 (en) * 2004-04-15 2008-08-19 Emmellen Biotech Pharmaceuticals Limited Process for preparation of optically active 1-erythro-2-amino-1-phenyl-1-propanol
US8076518B2 (en) 2005-03-28 2011-12-13 Albemarle Corporation Chain extenders
US7964695B2 (en) 2005-03-28 2011-06-21 Albemarle Corporation Chain extenders
CA2602352C (en) 2005-03-28 2011-04-26 Albemarle Corporation Diimines and secondary diamines
WO2007077140A1 (de) * 2006-01-06 2007-07-12 Basf Aktiengesellschaft Hydroxy-norephedrin-derivate und verfahren zu ihrer herstellung
GB0607911D0 (en) * 2006-04-21 2006-05-31 Ineos Fluor Holdings Ltd Process
US8143365B2 (en) 2007-01-10 2012-03-27 Albemarle Corporation Formulations for reaction injection molding and for spray systems
US8654740B2 (en) 2009-03-03 2014-02-18 Intel Corporation Polar cap reset method for differential codebook for wireless communications
CN103113237B (zh) * 2013-03-11 2014-04-30 苏州立新制药有限公司 一种盐酸利托君的制备方法
CN103113238B (zh) * 2013-03-11 2014-04-30 苏州立新制药有限公司 一种利托君的制备方法
CN103113239B (zh) * 2013-03-11 2014-04-30 苏州立新制药有限公司 盐酸利托君的制备方法
MX2017004065A (es) 2014-09-29 2017-07-24 Zogenix Int Ltd Sistema de control para el control de distribucion de medicacion.
RU2731179C2 (ru) * 2015-12-22 2020-08-31 Зодженикс Интернэшнл Лимитед Фенфлураминовые композиции и способы их получения
EP3393470B1 (de) 2015-12-22 2021-01-20 Zogenix International Limited Metabolitresistente fenfluraminanaloga und verfahren zur verwendung davon
JP2019526544A (ja) 2016-08-24 2019-09-19 ゾゲニクス インターナショナル リミテッド 5−ht2bアゴニストの形成を阻害するための製剤およびその使用方法
CN107311875A (zh) * 2017-06-30 2017-11-03 暨明医药科技(苏州)有限公司 重酒石酸间羟胺的合成方法
US10682317B2 (en) 2017-09-26 2020-06-16 Zogenix International Limited Ketogenic diet compatible fenfluramine formulation
US11571397B2 (en) 2018-05-11 2023-02-07 Zogenix International Limited Compositions and methods for treating seizure-induced sudden death
FR3102480B1 (fr) * 2019-10-29 2022-02-04 Commissariat Energie Atomique Matériaux spécifiques utilisables pour la détection d’au moins un élément alcalin
US11612574B2 (en) 2020-07-17 2023-03-28 Zogenix International Limited Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1956950A (en) * 1930-04-08 1934-05-01 Bilhuber Inc E Manufacture of laevo-1-phenyl-2-methylaminopropanol-1
EP0099416B1 (de) * 1982-07-20 1987-03-11 Union Carbide Corporation Kontinuierliches Verfahren zur Herstellung von Alkanolaminen
EP0853641A1 (de) * 1995-10-04 1998-07-22 The Dow Chemical Company Aminverkappte polyether und verfahren zu ihrer herstellung
GB9607917D0 (en) * 1996-04-17 1996-06-19 Swan Thomas & Co Ltd Supercritical hydrogenation
AU1798200A (en) * 1998-12-24 2000-07-31 Nagase & Company, Ltd. Process for producing l-erythro-(1r,2s)-2-amino-1-phenylpropan-1-ol
AU769421B2 (en) * 1999-12-13 2004-01-29 Victoria University Yeast-based process for production of L-pac
AUPQ462599A0 (en) 1999-12-13 2000-01-13 Polychip Pharmaceuticals Pty Ltd Yeast-based process for production of l-pac

Also Published As

Publication number Publication date
US20040249212A1 (en) 2004-12-09
EP1421055A1 (de) 2004-05-26
DE60226038D1 (de) 2008-05-21
EP1421055B1 (de) 2008-04-09
DE60226038T2 (de) 2009-05-14
WO2003018531A1 (en) 2003-03-06
US7176332B2 (en) 2007-02-13
AUPR732601A0 (en) 2001-09-20
JP2005500399A (ja) 2005-01-06
AU2002328659B2 (en) 2009-07-30
EP1421055A4 (de) 2005-01-19

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