ATE389029T1 - Protease assay zur kontrolle medikamentöser therapie - Google Patents
Protease assay zur kontrolle medikamentöser therapieInfo
- Publication number
- ATE389029T1 ATE389029T1 AT02790358T AT02790358T ATE389029T1 AT E389029 T1 ATE389029 T1 AT E389029T1 AT 02790358 T AT02790358 T AT 02790358T AT 02790358 T AT02790358 T AT 02790358T AT E389029 T1 ATE389029 T1 AT E389029T1
- Authority
- AT
- Austria
- Prior art keywords
- drug therapy
- control drug
- protease assay
- present
- concentration
- Prior art date
Links
- 108091005804 Peptidases Proteins 0.000 title 1
- 239000004365 Protease Substances 0.000 title 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 title 1
- 238000003556 assay Methods 0.000 title 1
- 238000002651 drug therapy Methods 0.000 title 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 abstract 2
- 239000000137 peptide hydrolase inhibitor Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000004166 bioassay Methods 0.000 abstract 1
- 238000001952 enzyme assay Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000001177 retroviral effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
- G01N2333/161—HIV-1, HIV-2 gag-pol, e.g. p55, p24/25, p17/18, p.7, p6, p66/68, p51/52, p31/34, p32, p40
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33111701P | 2001-11-08 | 2001-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE389029T1 true ATE389029T1 (de) | 2008-03-15 |
Family
ID=23292681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02790358T ATE389029T1 (de) | 2001-11-08 | 2002-11-08 | Protease assay zur kontrolle medikamentöser therapie |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7320878B2 (de) |
| EP (1) | EP1446498B1 (de) |
| JP (1) | JP2005513420A (de) |
| AT (1) | ATE389029T1 (de) |
| CA (1) | CA2466497A1 (de) |
| DE (1) | DE60225587T2 (de) |
| ES (1) | ES2302860T3 (de) |
| WO (1) | WO2003040390A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040014030A1 (en) * | 2002-07-18 | 2004-01-22 | Lili Arabshahi | Enzymatic assay of HIV protease inhibitors |
| CA2539924A1 (en) * | 2003-09-23 | 2005-04-07 | Light Sciences Corporation | Conjugates for photodynamic therapy |
| US20060199221A1 (en) * | 2005-03-07 | 2006-09-07 | Samad Talebpour | Correction for temperature dependence assays |
| WO2007079392A2 (en) * | 2005-12-30 | 2007-07-12 | The Trustees Of Columbia University In The City Of New York | Real-time assays of neuro-humoral to assess cardiovascular stress |
| US8185319B2 (en) * | 2006-01-19 | 2012-05-22 | Novx Systems Canada Inc. | Method of compensation of dose-response curve of an assay for sensitivity to perturbing variables |
| GB201402132D0 (en) * | 2014-02-07 | 2014-03-26 | South African Nuclear Energy | A method of producing ethylenedicysteine deoxyglucosamine (ECDG) or a salt thereof and its application in a kit |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1185881A (en) * | 1982-02-01 | 1985-04-23 | Jacques Degelaen | ENZYMATIC PROCESS FOR THE DETERMINATION OF .beta.-LACTAM ANTIBIOTICS |
| DE3531778A1 (de) * | 1985-09-06 | 1987-03-12 | Behringwerke Ag | Verfahren zur bestimmung von proteaseinhibitoren |
| EP0428000A1 (de) | 1989-11-03 | 1991-05-22 | Abbott Laboratories | Fluorogene Substrate zum Nachweis von proteolytischer Enzymaktivität |
| US5235039A (en) | 1991-06-10 | 1993-08-10 | Eli Lilly And Company | Substrates for hiv protease |
| DK0810209T3 (da) * | 1992-08-25 | 2002-08-12 | Monsanto Co | Alpha - and beta-aminosyre-hydroxyethylaminosulfonamider til anvendelse som inhibitorer af retrovirale proteaser |
| US5576177A (en) * | 1994-03-09 | 1996-11-19 | St. Jude Children's Research Hospital | Bioassay for reverse transcriptase inhibitors |
| SK283878B6 (sk) | 1996-01-26 | 2004-04-06 | Virco B.V.B.A. | In vitro spôsob určenia HIV chemoterapie HIV pozitívnych pacientov |
| KR100537153B1 (ko) | 1996-01-29 | 2006-12-15 | 바이럴러직, 인코퍼레이티드 | 항바이러스약품감수성및내성그리고항바이러스약물의스크리닝을결정하는방법및조성물 |
| JP3768304B2 (ja) | 1996-10-07 | 2006-04-19 | 株式会社松井製作所 | 冷媒設備用のバルブ |
| CA2283434A1 (en) * | 1997-03-07 | 1998-09-11 | Tropix, Inc. | Protease inhibitor assay |
| US6017723A (en) * | 1998-03-27 | 2000-01-25 | Long Island Jewish Medical Center | Method for isolating inhibitors of protease activity |
| CA2228821A1 (en) | 1998-04-16 | 1999-10-16 | Zhibo Gan | Pin method for measuring bioactive substance |
| ES2604662T3 (es) | 1998-06-23 | 2017-03-08 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Ensayo de acondicionamiento físico y métodos para reducir la resistencia del VIH a la terapia |
| AU2001233513A1 (en) | 2000-02-04 | 2001-08-14 | K.U. Leuven Research And Development | Hiv-1 resistance assay |
| WO2001079540A2 (en) | 2000-04-18 | 2001-10-25 | Virco Bvba | Methods for measuring drug resistance |
| JP2004510961A (ja) | 2000-09-15 | 2004-04-08 | ビルコ・ビーブイビーエイ | 疾患の処置のための薬物療法を最適化するシステムおよび方法 |
| AU2002223052B2 (en) | 2000-11-10 | 2007-09-20 | Eurofins Viralliance, Inc. | Novel method for analysing phenotypic characteristics of human immunodeficiency virus (HIV) |
-
2002
- 2002-11-08 AT AT02790358T patent/ATE389029T1/de not_active IP Right Cessation
- 2002-11-08 JP JP2003542636A patent/JP2005513420A/ja active Pending
- 2002-11-08 US US10/494,903 patent/US7320878B2/en not_active Expired - Fee Related
- 2002-11-08 DE DE60225587T patent/DE60225587T2/de not_active Expired - Fee Related
- 2002-11-08 WO PCT/EP2002/012631 patent/WO2003040390A2/en not_active Ceased
- 2002-11-08 ES ES02790358T patent/ES2302860T3/es not_active Expired - Lifetime
- 2002-11-08 CA CA002466497A patent/CA2466497A1/en not_active Abandoned
- 2002-11-08 EP EP02790358A patent/EP1446498B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1446498A2 (de) | 2004-08-18 |
| JP2005513420A (ja) | 2005-05-12 |
| EP1446498B1 (de) | 2008-03-12 |
| WO2003040390A3 (en) | 2003-09-25 |
| DE60225587D1 (de) | 2008-04-24 |
| WO2003040390A2 (en) | 2003-05-15 |
| CA2466497A1 (en) | 2003-05-15 |
| ES2302860T3 (es) | 2008-08-01 |
| US20050221286A1 (en) | 2005-10-06 |
| DE60225587T2 (de) | 2009-04-02 |
| US7320878B2 (en) | 2008-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |