ATE387501T1 - L-glutamatoxidase - Google Patents
L-glutamatoxidaseInfo
- Publication number
- ATE387501T1 ATE387501T1 AT01921904T AT01921904T ATE387501T1 AT E387501 T1 ATE387501 T1 AT E387501T1 AT 01921904 T AT01921904 T AT 01921904T AT 01921904 T AT01921904 T AT 01921904T AT E387501 T1 ATE387501 T1 AT E387501T1
- Authority
- AT
- Austria
- Prior art keywords
- molecular weight
- enzyme
- glutamate oxidase
- novel
- gene encoding
- Prior art date
Links
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 4
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108010069325 L-glutamate oxidase Proteins 0.000 abstract 3
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical compound OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 abstract 2
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 abstract 2
- 235000019162 flavin adenine dinucleotide Nutrition 0.000 abstract 2
- 239000011714 flavin adenine dinucleotide Substances 0.000 abstract 2
- 229940093632 flavin-adenine dinucleotide Drugs 0.000 abstract 2
- 229960002989 glutamic acid Drugs 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- HWXBTNAVRSUOJR-UHFFFAOYSA-N alpha-hydroxyglutaric acid Natural products OC(=O)C(O)CCC(O)=O HWXBTNAVRSUOJR-UHFFFAOYSA-N 0.000 abstract 1
- 229940009533 alpha-ketoglutaric acid Drugs 0.000 abstract 1
- 239000005515 coenzyme Substances 0.000 abstract 1
- 239000000539 dimer Substances 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
- C12Y104/03011—L-Glutamate oxidase (1.4.3.11)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000117749 | 2000-04-19 | ||
| JP2001057848 | 2001-03-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE387501T1 true ATE387501T1 (de) | 2008-03-15 |
Family
ID=26590377
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01921904T ATE387501T1 (de) | 2000-04-19 | 2001-04-19 | L-glutamatoxidase |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7109008B2 (de) |
| EP (1) | EP1277839B1 (de) |
| JP (1) | JP4002765B2 (de) |
| AT (1) | ATE387501T1 (de) |
| AU (1) | AU4879101A (de) |
| CA (1) | CA2406130C (de) |
| DE (1) | DE60132989T2 (de) |
| WO (1) | WO2001079503A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001079503A1 (en) * | 2000-04-19 | 2001-10-25 | Yamasa Corporation | L-glutamate oxidase |
| WO2014150883A1 (en) | 2013-03-15 | 2014-09-25 | Abbott Point Of Care Inc. | Glutamate oxidase mutagenesis for diagnostic testing |
| CN103388002A (zh) * | 2013-07-23 | 2013-11-13 | 江南大学 | 一种产l-谷氨酸氧化酶重组菌株的构建方法及其应用 |
| CN106282205B (zh) * | 2015-06-12 | 2021-06-01 | 上海市农业科学院 | 一种高比活l-谷氨酸氧化酶基因多位点突变体及其制备方法和应用 |
| CN105331642B (zh) * | 2015-11-30 | 2020-06-19 | 浙江汇宁生物科技有限公司 | 一种利用L-谷氨酸氧化酶催化生产α-酮戊二酸的方法 |
| CN107686850B (zh) * | 2016-08-04 | 2022-08-09 | 中国科学院天津工业生物技术研究所 | 一种利用共表达重组菌株转化生产α-酮戊二酸的方法 |
| JP6349452B1 (ja) | 2017-11-29 | 2018-06-27 | ヤマサ醤油株式会社 | Ｌ−グルタミン酸オキシダーゼ乾燥組成物 |
| CN110283837A (zh) * | 2019-04-19 | 2019-09-27 | 中国科学院天津工业生物技术研究所 | 一种高酶活性l-谷氨酸氧化酶突变体及其制备方法 |
| WO2021193598A1 (ja) | 2020-03-24 | 2021-09-30 | 味の素株式会社 | Ｌ－グルタミン酸オキシダーゼ変異体 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58149677A (ja) * | 1982-03-02 | 1983-09-06 | Toyo Jozo Co Ltd | Ｌ−グルタミン酸オキシダ−ゼ（ｈ↓２ｏ↓２・ジエネレイテイング）およびその製造法、ならびに分析方法 |
| AU565635B2 (en) | 1982-06-29 | 1987-09-24 | Yamasa Shoyu K.K. | L-glutamic acid oxidase |
| WO2001079503A1 (en) * | 2000-04-19 | 2001-10-25 | Yamasa Corporation | L-glutamate oxidase |
-
2001
- 2001-04-19 WO PCT/JP2001/003345 patent/WO2001079503A1/ja not_active Ceased
- 2001-04-19 DE DE60132989T patent/DE60132989T2/de not_active Expired - Lifetime
- 2001-04-19 EP EP01921904A patent/EP1277839B1/de not_active Expired - Lifetime
- 2001-04-19 AU AU48791/01A patent/AU4879101A/en not_active Abandoned
- 2001-04-19 CA CA002406130A patent/CA2406130C/en not_active Expired - Lifetime
- 2001-04-19 AT AT01921904T patent/ATE387501T1/de not_active IP Right Cessation
- 2001-04-19 US US10/257,398 patent/US7109008B2/en not_active Expired - Lifetime
- 2001-04-19 JP JP2001577486A patent/JP4002765B2/ja not_active Expired - Lifetime
-
2006
- 2006-04-07 US US11/399,446 patent/US20060228790A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1277839A1 (de) | 2003-01-22 |
| CA2406130C (en) | 2009-07-07 |
| AU4879101A (en) | 2001-10-30 |
| CA2406130A1 (en) | 2001-10-25 |
| WO2001079503A1 (en) | 2001-10-25 |
| DE60132989D1 (de) | 2008-04-10 |
| US20040091989A1 (en) | 2004-05-13 |
| EP1277839A4 (de) | 2004-05-12 |
| US7109008B2 (en) | 2006-09-19 |
| US20060228790A1 (en) | 2006-10-12 |
| DE60132989T2 (de) | 2009-02-19 |
| EP1277839B1 (de) | 2008-02-27 |
| JP4002765B2 (ja) | 2007-11-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |