ATE387456T1 - Kristallines solvat von cefuroximsäure mit acetonitril - Google Patents

Kristallines solvat von cefuroximsäure mit acetonitril

Info

Publication number
ATE387456T1
ATE387456T1 AT06112701T AT06112701T ATE387456T1 AT E387456 T1 ATE387456 T1 AT E387456T1 AT 06112701 T AT06112701 T AT 06112701T AT 06112701 T AT06112701 T AT 06112701T AT E387456 T1 ATE387456 T1 AT E387456T1
Authority
AT
Austria
Prior art keywords
acetonitrile
crystalline solvate
cefuroxime acid
cefuroxime
acid
Prior art date
Application number
AT06112701T
Other languages
English (en)
Inventor
Maurizio Zenoni
Angelo Giovanni Cattaneo
Original Assignee
Acs Dobfar Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa
Application granted granted Critical
Publication of ATE387456T1 publication Critical patent/ATE387456T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT06112701T 2005-05-13 2006-04-18 Kristallines solvat von cefuroximsäure mit acetonitril ATE387456T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000871A ITMI20050871A1 (it) 2005-05-13 2005-05-13 Solvato cristallino di cefuroxima acido

Publications (1)

Publication Number Publication Date
ATE387456T1 true ATE387456T1 (de) 2008-03-15

Family

ID=36763089

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06112701T ATE387456T1 (de) 2005-05-13 2006-04-18 Kristallines solvat von cefuroximsäure mit acetonitril

Country Status (9)

Country Link
US (1) US7615631B2 (de)
EP (1) EP1724273B1 (de)
KR (1) KR101310618B1 (de)
CN (1) CN1861608A (de)
AT (1) ATE387456T1 (de)
DE (1) DE602006000578D1 (de)
ES (1) ES2299144T3 (de)
IT (1) ITMI20050871A1 (de)
PT (1) PT1724273E (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102746323B (zh) * 2012-06-26 2014-05-07 天津大学 一种头孢呋辛酸的新晶型及其结晶制备方法
CN112480146B (zh) * 2020-10-30 2022-02-22 浙江惠迪森药业有限公司 一种头孢呋辛酸混合溶剂化物、晶型及制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
NL191844C (nl) * 1979-02-15 1996-09-03 Glaxo Group Ltd Werkwijze voor het bereiden van natriumcefuroxime.
IN190849B (de) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (de) 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
US20040092735A1 (en) 2002-11-08 2004-05-13 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefuroxime sodium

Also Published As

Publication number Publication date
US20060258636A1 (en) 2006-11-16
KR20060117199A (ko) 2006-11-16
CN1861608A (zh) 2006-11-15
EP1724273A1 (de) 2006-11-22
PT1724273E (pt) 2008-04-22
ES2299144T3 (es) 2008-05-16
ITMI20050871A1 (it) 2006-11-14
EP1724273B1 (de) 2008-02-27
KR101310618B1 (ko) 2013-09-24
US7615631B2 (en) 2009-11-10
DE602006000578D1 (de) 2008-04-10

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