ITMI20050871A1 - Solvato cristallino di cefuroxima acido - Google Patents

Solvato cristallino di cefuroxima acido

Info

Publication number
ITMI20050871A1
ITMI20050871A1 IT000871A ITMI20050871A ITMI20050871A1 IT MI20050871 A1 ITMI20050871 A1 IT MI20050871A1 IT 000871 A IT000871 A IT 000871A IT MI20050871 A ITMI20050871 A IT MI20050871A IT MI20050871 A1 ITMI20050871 A1 IT MI20050871A1
Authority
IT
Italy
Prior art keywords
cefuroxima
crystalline solvate
acid crystalline
acid
solvate
Prior art date
Application number
IT000871A
Other languages
English (en)
Inventor
Angelo Giovanni Cattaneo
Maurizio Zenoni
Original Assignee
Acs Dobfar Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa
Priority to IT000871A priority Critical patent/ITMI20050871A1/it
Priority to US11/379,132 priority patent/US7615631B2/en
Priority to PT06112701T priority patent/PT1724273E/pt
Priority to EP06112701A priority patent/EP1724273B1/en
Priority to DE602006000578T priority patent/DE602006000578D1/de
Priority to ES06112701T priority patent/ES2299144T3/es
Priority to AT06112701T priority patent/ATE387456T1/de
Priority to CNA2006100825438A priority patent/CN1861608A/zh
Priority to KR1020060038761A priority patent/KR101310618B1/ko
Publication of ITMI20050871A1 publication Critical patent/ITMI20050871A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT000871A 2005-05-13 2005-05-13 Solvato cristallino di cefuroxima acido ITMI20050871A1 (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT000871A ITMI20050871A1 (it) 2005-05-13 2005-05-13 Solvato cristallino di cefuroxima acido
US11/379,132 US7615631B2 (en) 2005-05-13 2006-04-18 Crystalline solvate of cefuroxime acid
PT06112701T PT1724273E (pt) 2005-05-13 2006-04-18 Solvato cristalino de ácido de cefuroxima com acetonitrilo
EP06112701A EP1724273B1 (en) 2005-05-13 2006-04-18 Crystalline acetonitrile solvate of cefuroxime acid
DE602006000578T DE602006000578D1 (de) 2005-05-13 2006-04-18 Kristallines Solvat von Cefuroximsäure mit Acetonitril
ES06112701T ES2299144T3 (es) 2005-05-13 2006-04-18 Solvato cristalino del acido de cefuroxima con acetonitrilo.
AT06112701T ATE387456T1 (de) 2005-05-13 2006-04-18 Kristallines solvat von cefuroximsäure mit acetonitril
CNA2006100825438A CN1861608A (zh) 2005-05-13 2006-04-28 头孢呋辛酸的结晶性溶剂化物
KR1020060038761A KR101310618B1 (ko) 2005-05-13 2006-04-28 세푸록심 산의 결정성 용매화물

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000871A ITMI20050871A1 (it) 2005-05-13 2005-05-13 Solvato cristallino di cefuroxima acido

Publications (1)

Publication Number Publication Date
ITMI20050871A1 true ITMI20050871A1 (it) 2006-11-14

Family

ID=36763089

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000871A ITMI20050871A1 (it) 2005-05-13 2005-05-13 Solvato cristallino di cefuroxima acido

Country Status (9)

Country Link
US (1) US7615631B2 (it)
EP (1) EP1724273B1 (it)
KR (1) KR101310618B1 (it)
CN (1) CN1861608A (it)
AT (1) ATE387456T1 (it)
DE (1) DE602006000578D1 (it)
ES (1) ES2299144T3 (it)
IT (1) ITMI20050871A1 (it)
PT (1) PT1724273E (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102746323B (zh) * 2012-06-26 2014-05-07 天津大学 一种头孢呋辛酸的新晶型及其结晶制备方法
CN112480146B (zh) * 2020-10-30 2022-02-22 浙江惠迪森药业有限公司 一种头孢呋辛酸混合溶剂化物、晶型及制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
ZA80844B (en) 1979-02-15 1981-08-26 Glaxo Group Ltd Preparation of sodium cefuroxime
IN190849B (it) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (de) 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
US20040092735A1 (en) 2002-11-08 2004-05-13 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefuroxime sodium

Also Published As

Publication number Publication date
DE602006000578D1 (de) 2008-04-10
CN1861608A (zh) 2006-11-15
EP1724273A1 (en) 2006-11-22
ES2299144T3 (es) 2008-05-16
KR20060117199A (ko) 2006-11-16
PT1724273E (pt) 2008-04-22
EP1724273B1 (en) 2008-02-27
KR101310618B1 (ko) 2013-09-24
ATE387456T1 (de) 2008-03-15
US20060258636A1 (en) 2006-11-16
US7615631B2 (en) 2009-11-10

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