PT1724273E - Solvato cristalino de ácido de cefuroxima com acetonitrilo - Google Patents

Solvato cristalino de ácido de cefuroxima com acetonitrilo Download PDF

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Publication number
PT1724273E
PT1724273E PT06112701T PT06112701T PT1724273E PT 1724273 E PT1724273 E PT 1724273E PT 06112701 T PT06112701 T PT 06112701T PT 06112701 T PT06112701 T PT 06112701T PT 1724273 E PT1724273 E PT 1724273E
Authority
PT
Portugal
Prior art keywords
acetonitrile solvate
cefuroxime acid
crystalline acetonitrile
cefuroxime
crystalline
Prior art date
Application number
PT06112701T
Other languages
English (en)
Inventor
Maurizio Zenoni
Angelo Giovanni Cattaneo
Original Assignee
Acs Dobfar Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa
Publication of PT1724273E publication Critical patent/PT1724273E/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT06112701T 2005-05-13 2006-04-18 Solvato cristalino de ácido de cefuroxima com acetonitrilo PT1724273E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000871A ITMI20050871A1 (it) 2005-05-13 2005-05-13 Solvato cristallino di cefuroxima acido

Publications (1)

Publication Number Publication Date
PT1724273E true PT1724273E (pt) 2008-04-22

Family

ID=36763089

Family Applications (1)

Application Number Title Priority Date Filing Date
PT06112701T PT1724273E (pt) 2005-05-13 2006-04-18 Solvato cristalino de ácido de cefuroxima com acetonitrilo

Country Status (9)

Country Link
US (1) US7615631B2 (pt)
EP (1) EP1724273B1 (pt)
KR (1) KR101310618B1 (pt)
CN (1) CN1861608A (pt)
AT (1) ATE387456T1 (pt)
DE (1) DE602006000578D1 (pt)
ES (1) ES2299144T3 (pt)
IT (1) ITMI20050871A1 (pt)
PT (1) PT1724273E (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102746323B (zh) * 2012-06-26 2014-05-07 天津大学 一种头孢呋辛酸的新晶型及其结晶制备方法
CN112480146B (zh) * 2020-10-30 2022-02-22 浙江惠迪森药业有限公司 一种头孢呋辛酸混合溶剂化物、晶型及制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985741A (en) * 1972-09-15 1976-10-12 Bristol-Myers Company Production of p-hydroxycephalexin
YU42325B (en) 1979-02-15 1988-08-31 Glaxo Group Ltd Process for obtaining sodium cefuroxim
IN190849B (pt) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
AT411996B (de) 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
US20040092735A1 (en) * 2002-11-08 2004-05-13 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefuroxime sodium

Also Published As

Publication number Publication date
US7615631B2 (en) 2009-11-10
US20060258636A1 (en) 2006-11-16
EP1724273A1 (en) 2006-11-22
ITMI20050871A1 (it) 2006-11-14
CN1861608A (zh) 2006-11-15
DE602006000578D1 (de) 2008-04-10
KR20060117199A (ko) 2006-11-16
ES2299144T3 (es) 2008-05-16
KR101310618B1 (ko) 2013-09-24
ATE387456T1 (de) 2008-03-15
EP1724273B1 (en) 2008-02-27

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PT1724273E (pt) Solvato cristalino de ácido de cefuroxima com acetonitrilo