PL374461A1 - Sposób otrzymywania pochodnych 13,14-dihydro-PGF - Google Patents

Sposób otrzymywania pochodnych 13,14-dihydro-PGF

Info

Publication number
PL374461A1
PL374461A1 PL374461A PL37446105A PL374461A1 PL 374461 A1 PL374461 A1 PL 374461A1 PL 374461 A PL374461 A PL 374461A PL 37446105 A PL37446105 A PL 37446105A PL 374461 A1 PL374461 A1 PL 374461A1
Authority
PL
Poland
Prior art keywords
pgf
dihydro
derivatives
obtaining
Prior art date
Application number
PL374461A
Other languages
English (en)
Other versions
PL212658B1 (pl
Inventor
Jacek Martynow
Julita Jozwik
Wieslaw Szelejewski
Osman Achmatowicz
Andrzej Kutner
Krzysztof Wisniewski
Jerzy Winiarski
Oliwia Zegrocka-Stendel
Piotr Golebiewski
Original Assignee
Instytut Farmaceutyczny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instytut Farmaceutyczny filed Critical Instytut Farmaceutyczny
Priority to PL374461A priority Critical patent/PL212658B1/pl
Priority to EP06733186A priority patent/EP1891005A2/en
Priority to PCT/PL2006/000023 priority patent/WO2006112742A2/en
Priority to US11/911,813 priority patent/US20090093651A1/en
Publication of PL374461A1 publication Critical patent/PL374461A1/pl
Priority to US11/874,218 priority patent/US7897793B2/en
Publication of PL212658B1 publication Critical patent/PL212658B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/12—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/10—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms two oxygen atoms and one sulfur atom, e.g. cyclic sulfates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
PL374461A 2005-04-18 2005-04-18 Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub> PL212658B1 (pl)

Priority Applications (5)

Application Number Priority Date Filing Date Title
PL374461A PL212658B1 (pl) 2005-04-18 2005-04-18 Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub>
EP06733186A EP1891005A2 (en) 2005-04-18 2006-04-18 Process for preparation of 13,14-dihydro-pgf2 alpha derivatives
PCT/PL2006/000023 WO2006112742A2 (en) 2005-04-18 2006-04-18 PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2α DERIVATIVES
US11/911,813 US20090093651A1 (en) 2005-04-18 2006-04-18 Process for preparation of 13,14-dihydro-pgf2 alpha derivatives
US11/874,218 US7897793B2 (en) 2005-04-18 2007-10-18 Process for preparation of 13,14-dihydro-PGF2 alpha derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL374461A PL212658B1 (pl) 2005-04-18 2005-04-18 Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub>

Publications (2)

Publication Number Publication Date
PL374461A1 true PL374461A1 (pl) 2006-10-30
PL212658B1 PL212658B1 (pl) 2012-11-30

Family

ID=36607535

Family Applications (1)

Application Number Title Priority Date Filing Date
PL374461A PL212658B1 (pl) 2005-04-18 2005-04-18 Sposób otrzymywania pochodnych 13,14-dihydro-PGF<sub>2</sub><sub>α</sub>

Country Status (4)

Country Link
US (2) US20090093651A1 (pl)
EP (1) EP1891005A2 (pl)
PL (1) PL212658B1 (pl)
WO (1) WO2006112742A2 (pl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3494955A1 (en) 2017-12-08 2019-06-12 Warszawski Uniwersytet Medyczny Cosmetic composition for promoting hair growth

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8546114B2 (en) 2006-01-18 2013-10-01 Chirogate International Inc. Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom
US7605178B2 (en) * 2006-07-10 2009-10-20 Allergan, Inc. Therapeutic compounds
IT1392492B1 (it) * 2008-12-24 2012-03-09 Ind Chimica Srl Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.
WO2011095990A2 (en) 2010-02-03 2011-08-11 Fdc Limited Process for the purification of prostaglandins and analogues thereof
EP2822927A1 (en) * 2012-03-09 2015-01-14 Instytut Farmaceutyczny PROCESS FOR PREPARATION OF PROSTAGLANDIN F2alpha ANALOGUES
HU231214B1 (hu) 2014-03-13 2021-11-29 CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. Új eljárás nagytisztaságú prosztaglandinok előállítására
JP7609438B2 (ja) * 2019-10-11 2025-01-07 国立大学法人東北大学 シクロペンタン化合物の製造方法、ラクトン化合物の製造方法、ジオール化合物の製造方法、および化合物
CN119823092A (zh) * 2025-03-14 2025-04-15 江苏华盛锂电材料股份有限公司 硫酸乙烯酯类化合物、合成方法及其在二次电池中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4412958A (en) * 1981-10-16 1983-11-01 Pfizer Inc. Stereospecific synthesis of 5-phenyl-2S-pentanol
US5321143A (en) * 1988-05-26 1994-06-14 Massachusetts Institute Of Technology Ruthenium-catalyzed production of cyclic sulfates
SE9702706D0 (sv) * 1997-07-11 1997-07-11 Pharmacia & Upjohn Ab Prostaglandin derivatives devoid of side-effects for the treatment of glaucoma
IL143477A (en) * 2001-05-31 2009-07-20 Finetech Pharmaceutical Ltd Process for the preparation of 17-phenyl-18,19,20-trinor-pgf2?? and its derivatives
AU2001233286B2 (en) * 2000-02-01 2006-04-06 Cayman Chemical Company, Incorporated Internal 1,15-lactones of fluprostenol and related prostaglandin F2alpha analogs and their use in the treatment of glaucoma and intraocular hypertension
KR100437873B1 (ko) * 2001-05-08 2004-06-26 연성정밀화학(주) 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질
GB0112699D0 (en) * 2001-05-24 2001-07-18 Resolution Chemicals Ltd Process for the preparation of prostglandins and analogues thereof
GB0126076D0 (en) * 2001-10-31 2001-12-19 Cascade Biochem Ltd Improvements relating to prostaglandins and their analogues

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3494955A1 (en) 2017-12-08 2019-06-12 Warszawski Uniwersytet Medyczny Cosmetic composition for promoting hair growth

Also Published As

Publication number Publication date
PL212658B1 (pl) 2012-11-30
US20080207926A1 (en) 2008-08-28
US7897793B2 (en) 2011-03-01
WO2006112742A2 (en) 2006-10-26
EP1891005A2 (en) 2008-02-27
US20090093651A1 (en) 2009-04-09
WO2006112742A3 (en) 2006-12-28

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