ATE374603T1 - Amphiphile lipid-nanopartikel zur peptid- und/oder proteininkorporation - Google Patents
Amphiphile lipid-nanopartikel zur peptid- und/oder proteininkorporationInfo
- Publication number
- ATE374603T1 ATE374603T1 AT01995691T AT01995691T ATE374603T1 AT E374603 T1 ATE374603 T1 AT E374603T1 AT 01995691 T AT01995691 T AT 01995691T AT 01995691 T AT01995691 T AT 01995691T AT E374603 T1 ATE374603 T1 AT E374603T1
- Authority
- AT
- Austria
- Prior art keywords
- peptide
- lipid nanoparticles
- amphiphilic lipid
- protein incorporation
- incorporation
- Prior art date
Links
- 238000010348 incorporation Methods 0.000 title 1
- 150000002632 lipids Chemical class 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5123—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00128555 | 2000-12-27 | ||
| EP01125742 | 2001-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE374603T1 true ATE374603T1 (de) | 2007-10-15 |
Family
ID=26071689
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01995691T ATE374603T1 (de) | 2000-12-27 | 2001-12-17 | Amphiphile lipid-nanopartikel zur peptid- und/oder proteininkorporation |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20040081688A1 (de) |
| EP (1) | EP1345597B1 (de) |
| JP (1) | JP4072057B2 (de) |
| AR (1) | AR032073A1 (de) |
| AT (1) | ATE374603T1 (de) |
| AU (1) | AU2002226374B2 (de) |
| CA (1) | CA2431888C (de) |
| CY (1) | CY1106995T1 (de) |
| DE (1) | DE60130791T2 (de) |
| DK (1) | DK1345597T3 (de) |
| ES (1) | ES2291379T3 (de) |
| IL (2) | IL156531A0 (de) |
| PT (1) | PT1345597E (de) |
| SI (1) | SI1345597T1 (de) |
| WO (1) | WO2002051390A2 (de) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050208083A1 (en) | 2003-06-04 | 2005-09-22 | Nanobio Corporation | Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof |
| EP1633322A2 (de) * | 2003-06-04 | 2006-03-15 | Nanobio Corporation | Zusammensetzungen zur inaktivierung von pathogenen mikroorganismen, verfahren zur herstellung der zusammensetzungen und anwendungsverfahren dafür |
| EA200600877A1 (ru) * | 2003-10-31 | 2006-12-29 | Тева Фармасьютикал Индастриз, Лтд. | Наночастицы для доставки лекарств |
| CA2549966A1 (en) * | 2003-12-24 | 2005-07-07 | Ltt Bio-Pharma Co., Ltd. | Drug-containing nanoparticle, process for producing the same and parenterally administered preparation from the nanoparticle |
| FR2868704B1 (fr) * | 2004-04-07 | 2007-09-14 | Ethypharm Sa | Utilisation de lipides pour ameliorer la biodisponibilite de principes actifs proteiques en formulations injectables sous cutanees ou intra-musculaires |
| JP5368793B2 (ja) | 2005-07-18 | 2013-12-18 | ユニバーシティ オブ マサチューセッツ ロウエル | ナノエマルジョンを製造および使用するための組成物および方法 |
| EP1951200A2 (de) * | 2005-08-09 | 2008-08-06 | Nanobio Corporation | Eine nanoemulsion enthaltende zusammensetzungen mit entzündungshemmender wirkung |
| US20090098205A1 (en) * | 2005-09-15 | 2009-04-16 | Council Of Scientife & Industrial Research | pH SENSITIVE NANOPARTICLE FORMULATION FOR ORAL DELIVERY OF PROTEINS/PEPTIDES |
| PT3144013T (pt) * | 2005-12-01 | 2019-02-07 | Univ Massachusetts Lowell | Nanoemulsões botulínicas |
| US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| WO2007106683A2 (en) * | 2006-03-10 | 2007-09-20 | The Trustees Of The University Of Pennsylvania | Biomimetic iron-oxide-containing lipoprotein and related materials |
| WO2008070538A2 (en) | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Micellar nanoparticles comprising botulinum toxin |
| AU2007353340A1 (en) | 2006-12-01 | 2008-11-20 | Anterios, Inc. | Peptide nanoparticles and uses therefor |
| KR100834687B1 (ko) * | 2007-02-21 | 2008-06-02 | 주식회사 엘지생활건강 | 히노키티올 함유 지질 나노 입자 및 그의 제조방법 |
| CA2688415C (en) | 2007-05-31 | 2015-11-10 | Anterios, Inc. | Nucleic acid nanoparticles and uses therefor |
| CN101322719B (zh) * | 2007-06-15 | 2012-03-07 | 杭州民生药业有限公司 | 一种三氧化二砷固体脂质纳米粒及其制剂 |
| WO2010005726A2 (en) | 2008-06-16 | 2010-01-14 | Bind Biosciences Inc. | Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same |
| ES2765240T3 (es) | 2008-06-16 | 2020-06-08 | Pfizer | Nanopartículas poliméricas cargadas de fármaco y procedimientos de fabricación y uso de las mismas |
| EA020753B1 (ru) | 2008-06-16 | 2015-01-30 | Бинд Терапьютикс, Инк. | Терапевтические полимерные наночастицы, содержащие алкалоиды vinca, и их применение |
| US20110212157A1 (en) * | 2008-06-26 | 2011-09-01 | Anterios, Inc. | Dermal delivery |
| WO2010068866A2 (en) | 2008-12-12 | 2010-06-17 | Bind Biosciences | Therapeutic particles suitable for parenteral administration and methods of making and using same |
| ES2776126T3 (es) * | 2008-12-15 | 2020-07-29 | Pfizer | Nanopartículas de circulación prolongada para la liberación sostenida de agentes terapéuticos |
| EP2266546A1 (de) | 2009-06-08 | 2010-12-29 | Advancell Advanced in Vitro Cell Technologies,S.A. | Verfahren zur Herstellung kolloidaler Systeme zur Abgabe von Wirkstoffen |
| BR112012000826B1 (pt) | 2009-07-06 | 2022-07-26 | Variation Biotechnologies Inc | Método para a preparação de vesículas |
| CA2803282C (en) | 2009-07-06 | 2018-05-01 | David E. Anderson | Methods for preparing vesicles and formulations produced therefrom |
| WO2011072218A2 (en) | 2009-12-11 | 2011-06-16 | Bind Biosciences | Stable formulations for lyophilizing therapeutic particles |
| WO2011084513A2 (en) | 2009-12-15 | 2011-07-14 | Bind Biosciences, Inc. | Therapeutic polymeric nanoparticle compositions with high glass transition temperature or high molecular weight copolymers |
| WO2012006367A2 (en) | 2010-07-06 | 2012-01-12 | Variation Biotechnologies, Inc. | Compositions and methods for treating influenza |
| KR20130100290A (ko) | 2010-08-30 | 2013-09-10 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 협착성 병변을 위한 전단 제어 방출 및 혈전 용해 치료법 |
| US20130323280A1 (en) * | 2011-01-13 | 2013-12-05 | Variation Biotechnologies, Inc. | Methods for preparing vesicles and formulations produced therefrom |
| CA2862864C (en) | 2011-01-13 | 2018-12-11 | Variation Biotechnologies Inc. | Compositions and methods for treating viral infections |
| US20120189677A1 (en) * | 2011-01-20 | 2012-07-26 | Stephen Tonge | Formulations |
| DE102011116069A1 (de) | 2011-10-18 | 2013-04-18 | Dr. Rimpler Gmbh | Lipidnanopartikeldispersion, Verfahren zu deren Herstellung sowie ihre Verwendung |
| EP2802353A4 (de) | 2012-01-12 | 2015-12-02 | Variation Biotechnologies Inc | Zusammensetzungen und verfahren zur behandlung von virusinfektionen |
| CN104244984B (zh) | 2012-01-27 | 2020-03-31 | 变异生物技术公司 | 用于治疗剂的方法和组合物 |
| PT2895156T (pt) | 2012-09-17 | 2019-06-28 | Pfizer | Processo para a preparação de nanopartículas terapêuticas |
| WO2014092596A1 (ru) * | 2012-12-12 | 2014-06-19 | Vitkalova Tamara Aleksandrovna | Субстанции и фармацевтические композиции на их основе для лечения заболеваний человека, в том числе, для лечения хронических вирусных гепатитов "в" и "с" |
| US9693958B2 (en) * | 2013-03-15 | 2017-07-04 | Cureport, Inc. | Methods and devices for preparation of lipid nanoparticles |
| SI3116547T1 (sl) | 2014-03-14 | 2019-08-30 | Pfizer, Inc. | Terapevtski nanodelci, ki obsegajo terapevtsko stredstvo, in postopek izdelave ter uporabe le-teh |
| WO2015148483A1 (en) * | 2014-03-24 | 2015-10-01 | University Of Mississippi | Systems and methods for preparing solid lipid nanoparticles |
| JP2019535829A (ja) | 2016-11-21 | 2019-12-12 | エイリオン セラピューティクス, インコーポレイテッド | 大型薬剤の経皮送達 |
| IL267923B2 (en) * | 2018-08-02 | 2023-06-01 | Grifols Worldwide Operations Ltd | The composition containing the most concentrated alpha-1 type protein inhibitor and a method for obtaining it |
| JP7376582B2 (ja) * | 2018-10-22 | 2023-11-08 | イーオーイー オレオ ゲーエムベーハー | 成形体への圧縮を目的とした粉末材料用添加剤 |
| JP2020152673A (ja) | 2019-03-20 | 2020-09-24 | 株式会社リコー | ナノ粒子及びナノ粒子の製造方法、並びに医薬 |
| CN111388451B (zh) * | 2020-04-29 | 2023-05-23 | 南京工业大学 | 蛋白自组装铁基纳米粒及其制备方法与抗肿瘤药物递送系统中的应用 |
| WO2022072348A1 (en) | 2020-09-29 | 2022-04-07 | Oxford University Innovation Limited | Stroke treatment |
| CN113952301A (zh) * | 2021-11-17 | 2022-01-21 | 胡振华 | 中链脂肪酸作为促吸收剂制备药物组合物乳剂的应用 |
| DE202023100649U1 (de) | 2023-02-10 | 2023-03-22 | Cineolux Gmbh | Dispersion und Zubereitung zur topischen Anwendung |
| DE102023103292A1 (de) | 2023-02-10 | 2024-08-14 | Cineolux Gmbh | Dispersion und Zubereitung zur topischen Anwendung |
| WO2024259158A2 (en) * | 2023-06-13 | 2024-12-19 | Cornell University | Lipid nanoparticles for peptide delivery and methods of making and using the same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2608942B1 (fr) * | 1986-12-31 | 1991-01-11 | Centre Nat Rech Scient | Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules |
| IE904098A1 (en) * | 1989-11-13 | 1991-05-22 | Nova Pharm Corp | Lipospheres for controlled delivery of substances |
| US6165500A (en) * | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| US5665379A (en) * | 1990-09-28 | 1997-09-09 | Pharmacia & Upjohn Aktiebolag | Lipid particle forming matrix, preparation and use thereof |
| US5858398A (en) * | 1994-11-03 | 1999-01-12 | Isomed Inc. | Microparticular pharmaceutical compositions |
| US6143276A (en) * | 1997-03-21 | 2000-11-07 | Imarx Pharmaceutical Corp. | Methods for delivering bioactive agents to regions of elevated temperatures |
| IT1296914B1 (it) * | 1997-12-01 | 1999-08-03 | Maria Rosa Gasco | Composizione farmaceutica comprendente microparticelle atte al passaggio transmucosale ed al superamento della barriera |
| DE19819273A1 (de) * | 1998-04-30 | 1999-11-11 | Pharmatec International S Giul | Pharmazeutische Ciclosporin-Formulierung mit verbesserten biopharmazeutischen Eigenschaften, erhöhter physikalischer Qualität und Stabilität sowie Verfahren zur Herstellung |
| US6967028B2 (en) * | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
-
2001
- 2001-12-17 DK DK01995691T patent/DK1345597T3/da active
- 2001-12-17 WO PCT/EP2001/014877 patent/WO2002051390A2/en not_active Ceased
- 2001-12-17 US US10/451,985 patent/US20040081688A1/en not_active Abandoned
- 2001-12-17 PT PT01995691T patent/PT1345597E/pt unknown
- 2001-12-17 SI SI200130782T patent/SI1345597T1/sl unknown
- 2001-12-17 AT AT01995691T patent/ATE374603T1/de active
- 2001-12-17 IL IL15653101A patent/IL156531A0/xx unknown
- 2001-12-17 EP EP01995691A patent/EP1345597B1/de not_active Expired - Lifetime
- 2001-12-17 DE DE60130791T patent/DE60130791T2/de not_active Expired - Lifetime
- 2001-12-17 ES ES01995691T patent/ES2291379T3/es not_active Expired - Lifetime
- 2001-12-17 CA CA2431888A patent/CA2431888C/en not_active Expired - Fee Related
- 2001-12-17 JP JP2002552536A patent/JP4072057B2/ja not_active Expired - Fee Related
- 2001-12-17 AU AU2002226374A patent/AU2002226374B2/en not_active Ceased
- 2001-12-27 AR ARP010106066A patent/AR032073A1/es unknown
-
2003
- 2003-06-19 IL IL156531A patent/IL156531A/en not_active IP Right Cessation
-
2007
- 2007-11-08 CY CY20071101446T patent/CY1106995T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1345597B1 (de) | 2007-10-03 |
| JP2004519447A (ja) | 2004-07-02 |
| EP1345597A2 (de) | 2003-09-24 |
| WO2002051390A2 (en) | 2002-07-04 |
| CY1106995T1 (el) | 2012-09-26 |
| DK1345597T3 (da) | 2007-12-10 |
| CA2431888C (en) | 2010-06-01 |
| US20040081688A1 (en) | 2004-04-29 |
| ES2291379T3 (es) | 2008-03-01 |
| JP4072057B2 (ja) | 2008-04-02 |
| DE60130791T2 (de) | 2008-07-17 |
| IL156531A0 (en) | 2004-01-04 |
| IL156531A (en) | 2008-11-03 |
| AR032073A1 (es) | 2003-10-22 |
| CA2431888A1 (en) | 2002-07-04 |
| PT1345597E (pt) | 2007-10-29 |
| AU2002226374B2 (en) | 2006-06-08 |
| SI1345597T1 (sl) | 2007-12-31 |
| WO2002051390A3 (en) | 2002-10-10 |
| DE60130791D1 (de) | 2007-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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