ATE373491T1 - Bioaktive oberflächen-modifizierer für polymere und die daraus hergestellten gegenstände - Google Patents

Bioaktive oberflächen-modifizierer für polymere und die daraus hergestellten gegenstände

Info

Publication number
ATE373491T1
ATE373491T1 AT02732278T AT02732278T ATE373491T1 AT E373491 T1 ATE373491 T1 AT E373491T1 AT 02732278 T AT02732278 T AT 02732278T AT 02732278 T AT02732278 T AT 02732278T AT E373491 T1 ATE373491 T1 AT E373491T1
Authority
AT
Austria
Prior art keywords
polymers
oligo
central portion
segment
oligomeric
Prior art date
Application number
AT02732278T
Other languages
English (en)
Inventor
Paul Santerre
Original Assignee
Interface Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interface Biologics Inc filed Critical Interface Biologics Inc
Application granted granted Critical
Publication of ATE373491T1 publication Critical patent/ATE373491T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
    • C08G18/6415—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63 having nitrogen
    • C08G18/6446—Proteins and derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0017—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using a surface active agent
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/2805—Compounds having only one group containing active hydrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/2805—Compounds having only one group containing active hydrogen
    • C08G18/288—Compounds containing at least one heteroatom other than oxygen or nitrogen
    • C08G18/2885—Compounds containing at least one heteroatom other than oxygen or nitrogen containing halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/42—Polycondensates having carboxylic or carbonic ester groups in the main chain
    • C08G18/44—Polycarbonates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/4854—Polyethers containing oxyalkylene groups having four carbon atoms in the alkylene group
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/64—Macromolecular compounds not provided for by groups C08G18/42 - C08G18/63
    • C08G18/6484—Polysaccharides and derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/77—Polyisocyanates or polyisothiocyanates having heteroatoms in addition to the isocyanate or isothiocyanate nitrogen and oxygen or sulfur
    • C08G18/771—Polyisocyanates or polyisothiocyanates having heteroatoms in addition to the isocyanate or isothiocyanate nitrogen and oxygen or sulfur oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/002—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds
    • C08G65/005—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds containing halogens
    • C08G65/007—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from unsaturated compounds containing halogens containing fluorine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyethers (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
AT02732278T 2001-06-07 2002-06-03 Bioaktive oberflächen-modifizierer für polymere und die daraus hergestellten gegenstände ATE373491T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA002349989A CA2349989A1 (en) 2001-06-07 2001-06-07 Bioactive surface modifiers for polymers and articles made therefrom

Publications (1)

Publication Number Publication Date
ATE373491T1 true ATE373491T1 (de) 2007-10-15

Family

ID=4169231

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02732278T ATE373491T1 (de) 2001-06-07 2002-06-03 Bioaktive oberflächen-modifizierer für polymere und die daraus hergestellten gegenstände

Country Status (9)

Country Link
US (1) US6770725B2 (de)
EP (1) EP1418946B1 (de)
AT (1) ATE373491T1 (de)
AU (1) AU2002304926B2 (de)
CA (2) CA2349989A1 (de)
DE (1) DE60222563T2 (de)
ES (1) ES2294134T3 (de)
NZ (1) NZ529795A (de)
WO (1) WO2002098477A2 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7485719B2 (en) * 2003-02-21 2009-02-03 Terumo Kabushiki Kaisha Crosslinkable polysaccharide derivative, process for producing the same, crosslinkable polysaccharide composition, and medical treatment material
US7220816B2 (en) * 2003-12-16 2007-05-22 Advanced Cardiovascular Systems, Inc. Biologically absorbable coatings for implantable devices based on poly(ester amides) and methods for fabricating the same
GB0401202D0 (en) * 2004-01-20 2004-02-25 Ucl Biomedica Plc Polymer for use in conduits and medical devices
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
CA2467321A1 (en) * 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
US7556149B2 (en) 2004-06-07 2009-07-07 Ultimed, Inc. Sharps container for safe transportation and dispensing of unused pen needle assemblies and for safe storage of used pen needle assemblies
WO2007004067A2 (en) * 2005-04-15 2007-01-11 Interface Biologics Inc. Methods and compositions for the delivery of biologically active agents
EP2213293A3 (de) * 2005-12-08 2011-09-28 The Polymer Technology Group Incorporated Selbstanordnende Monomere und Oligomere als oberflächenmodifizierende Endgruppen für Polymere
AU2007207579A1 (en) * 2006-01-17 2007-07-26 Interface Biologics, Inc. Alcohol and water repellent non-woven fabrics
WO2007148230A2 (en) * 2006-04-14 2007-12-27 Interface Biologics Incorporated Grafted polymers and uses thereof
AU2007315790A1 (en) * 2006-06-30 2008-05-08 Interface Biologics, Inc. Bioresponsive polymers
WO2008098366A1 (en) * 2007-02-14 2008-08-21 Mount Sinai Hospital Fibrous scaffold for use in soft tissue engineering
CA2701186C (en) * 2007-10-05 2017-09-19 Interface Biologics Inc. Oligofluorinated cross-linked polymers and uses thereof
US8796248B2 (en) 2007-10-05 2014-08-05 Nektar Therapeutics Oligomer-corticosteroid conjugates
EP2214748B1 (de) * 2007-10-19 2016-12-07 Interface Biologics Inc. Selbsteliminierende beschichtungen
DE102007062273A1 (de) * 2007-12-14 2009-06-18 Aesculap Ag Fluoriertes Implantat
US20090242479A1 (en) * 2008-03-27 2009-10-01 General Electric Company Aromatic halosulfonyl isocyanate compositions
US8440176B2 (en) * 2008-04-25 2013-05-14 Interface Biologics, Inc. Covalently grafted pharmaceutically active polymers
WO2010141027A1 (en) * 2009-06-05 2010-12-09 Virginia Tech Intellectual Properties, Inc. Electromagnetic controlled biofabrication for manufactcuring of mimetic biocompatible materials
US8535655B2 (en) 2008-10-10 2013-09-17 Polyactiva Pty Ltd. Biodegradable polymer—bioactive moiety conjugates
DK2355853T3 (en) * 2008-10-10 2017-03-06 Polyactiva Pty Ltd BIODEGRADABLE POLYMER-BIOACTIVE FRAGMENT CONJUGATES
CA2716502C (en) 2009-05-15 2015-06-16 Interface Biologics, Inc. Antithrombogenic hollow fiber membranes and filters
US8160712B1 (en) 2009-09-23 2012-04-17 Marcy Freed Apparatus and method for treating sleep apnea
CN102933658A (zh) * 2009-12-18 2013-02-13 界面生物公司 从自组装涂层局部递送药物
WO2011141341A1 (en) 2010-05-14 2011-11-17 Iberhospitex, S.A. Compounds for the synthesis of biostable polyurethane, polyurea or polyurea urethane polymers
US8583240B2 (en) 2011-07-18 2013-11-12 Marcy L. Freed Device and method for treating dysphagia with electrical stimulation
US9140684B2 (en) 2011-10-27 2015-09-22 University Of Washington Through Its Center For Commercialization Device to expose cells to fluid shear forces and associated systems and methods
US9320465B2 (en) 2012-06-25 2016-04-26 International Business Machines Corporation Bio-chips and nano-biochips
US9574107B2 (en) 2015-02-16 2017-02-21 International Business Machines Corporation Fluoro-alcohol additives for orientation control of block copolymers
BR112017022668B1 (pt) 2015-04-24 2021-10-05 Lubrizol Advanced Materials, Inc Composição de polímero de superfície modificada recozida, método para preparar uma composição de polímero de superfície modificada recozida, e, artigo
US10827757B2 (en) 2015-10-12 2020-11-10 Lubrizol Advanced Materials, Inc. Biocidally active polymer compositions
BR112019007896B1 (pt) 2016-10-18 2022-11-08 Interface Biologics, Inc Composição misturada, artigo e seu método de produção
EP3630212A4 (de) * 2017-05-30 2021-02-24 Evonik Canada Inc. Gefässprothesen mit einer modifizierten oberfläche
CA3065256A1 (en) * 2017-05-30 2018-12-06 Evonik Canada Inc. Prosthetic valves having a modified surface
JP7502186B2 (ja) 2018-02-02 2024-06-18 リップル セラピューティクス コーポレーション ステロイド二量体を含むガラス製剤およびその使用
JP2021531061A (ja) 2018-05-22 2021-11-18 インターフェース バイオロジクス，インコーポレーテッド 薬物を脈管壁に送達するための組成物及び方法
CN115956083A (zh) 2020-05-01 2023-04-11 波纹疗法公司 异二聚体组合物及用于治疗眼部病症的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4861830A (en) 1980-02-29 1989-08-29 Th. Goldschmidt Ag Polymer systems suitable for blood-contacting surfaces of a biomedical device, and methods for forming
US5235003A (en) 1985-01-04 1993-08-10 Thoratec Laboratories Corporation Polysiloxane-polylactone block copolymers
JP2502059B2 (ja) 1986-02-05 1996-05-29 旭硝子株式会社 汚れ除去性の高い撥水撥油剤
EP0533809B1 (de) * 1990-06-14 1997-07-30 Vitaphore Corporation Polyurethan-biopolymer verbindung
US5589563A (en) * 1992-04-24 1996-12-31 The Polymer Technology Group Surface-modifying endgroups for biomedical polymers
US5405919A (en) * 1992-08-24 1995-04-11 The United States Of America As Represented By The Secretary Of Health And Human Services Polymer-bound nitric oxide/nucleophile adduct compositions, pharmaceutical compositions and methods of treating biological disorders
CA2228505C (en) * 1995-08-03 2007-11-06 Paul J. Santerre Fluoroligomer surface modifiers for polymers and articles made therefrom
DE69708461T2 (de) 1996-02-15 2002-06-27 Marc W. Mittelman Bioresponsive pharmakologisch aktive polymere und daraus hergestellte gegenstände
US5954966A (en) 1997-01-31 1999-09-21 University Of Ottawa Membrane composition and method of preparation
US6503538B1 (en) * 2000-08-30 2003-01-07 Cornell Research Foundation, Inc. Elastomeric functional biodegradable copolyester amides and copolyester urethanes

Also Published As

Publication number Publication date
CA2349989A1 (en) 2002-12-07
DE60222563T2 (de) 2008-07-10
DE60222563D1 (de) 2007-10-31
NZ529795A (en) 2005-06-24
EP1418946A2 (de) 2004-05-19
ES2294134T3 (es) 2008-04-01
US20030097120A1 (en) 2003-05-22
US6770725B2 (en) 2004-08-03
WO2002098477A2 (en) 2002-12-12
WO2002098477A3 (en) 2004-02-05
CA2462529C (en) 2010-02-02
CA2462529A1 (en) 2002-12-12
AU2002304926B2 (en) 2007-10-04
EP1418946B1 (de) 2007-09-19

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