ATE369367T1 - Phenanthridiniumderivate als dna-bindende mittel - Google Patents

Phenanthridiniumderivate als dna-bindende mittel

Info

Publication number
ATE369367T1
ATE369367T1 AT04798693T AT04798693T ATE369367T1 AT E369367 T1 ATE369367 T1 AT E369367T1 AT 04798693 T AT04798693 T AT 04798693T AT 04798693 T AT04798693 T AT 04798693T AT E369367 T1 ATE369367 T1 AT E369367T1
Authority
AT
Austria
Prior art keywords
compounds
phenanthridinium
dip
dna
binding agents
Prior art date
Application number
AT04798693T
Other languages
English (en)
Inventor
Alexis Parenty
Leroy Cronin
Robert Brown
Original Assignee
Univ Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Glasgow filed Critical Univ Glasgow
Application granted granted Critical
Publication of ATE369367T1 publication Critical patent/ATE369367T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00Other synthetic dyes of known constitution

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT04798693T 2003-11-26 2004-11-26 Phenanthridiniumderivate als dna-bindende mittel ATE369367T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0327524.5A GB0327524D0 (en) 2003-11-26 2003-11-26 Heterocyclic aromatic compounds

Publications (1)

Publication Number Publication Date
ATE369367T1 true ATE369367T1 (de) 2007-08-15

Family

ID=29797871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04798693T ATE369367T1 (de) 2003-11-26 2004-11-26 Phenanthridiniumderivate als dna-bindende mittel

Country Status (6)

Country Link
US (1) US7947703B2 (de)
EP (1) EP1692130B1 (de)
AT (1) ATE369367T1 (de)
DE (1) DE602004008108D1 (de)
GB (1) GB0327524D0 (de)
WO (1) WO2005054241A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101035523A (zh) 2004-07-09 2007-09-12 西格马-奥利奇有限公司 旋光增加的手性离子液体
CA2574460A1 (en) 2004-07-23 2006-02-02 Sigma-Aldrich Co. High stability diionic liquid salts
US8168830B2 (en) 2004-07-23 2012-05-01 Sigma-Aldrich Co. Llc High stability diionic liquid salts
US8716472B2 (en) * 2006-10-16 2014-05-06 University Of Rochester Tripodal cyclohexane derivatives and their use as carbohydrate receptors
US8097721B2 (en) 2007-01-31 2012-01-17 Sigma-Aldrich Co. Llc High stability polyionic liquid salts
US9957291B2 (en) 2013-08-05 2018-05-01 Pacific Biosciences Of California, Inc. Protected fluorescent reagent compounds
EP3258952A4 (de) 2015-02-04 2018-12-05 Pacific Biosciences Of California, Inc. Multimere geschützte fluoreszierende reagenzien
US10676788B2 (en) 2015-11-20 2020-06-09 Pacific Biosciences Of California, Inc. Modified nucleotide reagents
EP4219506A1 (de) 2015-11-20 2023-08-02 Pacific Biosciences Of California, Inc. Geschützte farbstoffmarkierte reagenzien
CN113321943A (zh) 2015-11-20 2021-08-31 加利福尼亚太平洋生物科学股份有限公司 标记的核苷酸类似物、反应混合物以及测序方法和系统

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783687A (en) * 1990-03-14 1998-07-21 The Regents Of The University Of California Dyes designed for high sensitivity detection of double-stranded DNA
US5401847A (en) * 1990-03-14 1995-03-28 Regents Of The University Of California DNA complexes with dyes designed for energy transfer as fluorescent markers
DE69435240D1 (de) 1993-06-30 2009-10-29 Abbott Lab Interkalatoren mit DNA-Affinität und Anwendungsverfahren
US5561042A (en) 1994-07-22 1996-10-01 Cancer Therapy And Research Center Diamine platinum naphthalimide complexes as antitumor agents
US6743588B2 (en) 2001-01-11 2004-06-01 Tosoh Corporation Fluorescent dye and method of measuring nucleic acid

Also Published As

Publication number Publication date
DE602004008108D1 (de) 2007-09-20
EP1692130A2 (de) 2006-08-23
US7947703B2 (en) 2011-05-24
US20070249652A1 (en) 2007-10-25
WO2005054241A3 (en) 2005-07-28
EP1692130B1 (de) 2007-08-08
WO2005054241A2 (en) 2005-06-16
GB0327524D0 (en) 2003-12-31

Similar Documents

Publication Publication Date Title
MX2019005777A (es) Compuestos de n-(3fluoropropil)-pirrolidina sustituidos novedosos, procesos para su preparacion y usos terapeuticos de los mismos.
TW200510381A (en) Novel 2-pyridinecarboxamide derivatives
ATE338461T1 (de) Pyrazolpyrimidinfungizide
NO20052976L (no) Fosfodiesterase-4-inhibitorer.
ATE490253T1 (de) Synthese von 5-substituierten 7-azaindolen und 7- azaindolinen
NO20062633L (no) Pyrazolderivater som proteinkinasemodulatorer
NO20066015L (no) Fuserte heterosykliske forbindelser
NO20066055L (no) Pyridinderivater
TW200633991A (en) Chemical compounds
NO20075312L (no) N-(N-sulfonylaminometyl)cyklopropankarboksamidderivater nyttige ved smertebehandling
NO20075809L (no) DNA-PK inhibitorer
MX2007008308A (es) Derivados de n-(heteroaril)-1h-indol-2-carboxamidas y su utilizacion como ligandos del receptor vaniloide trpv1-.
ATE369367T1 (de) Phenanthridiniumderivate als dna-bindende mittel
CO5261496A1 (es) Derivados de heterociclo-alquilsulfonil-pirazol como agentes antiinflamatorios/analgesicos
ATE368040T1 (de) Substituierte tetrazyklische pyprolochinolonderivate als phosphodiesterase- inhibitoren
ATE498600T1 (de) Inden derivate als pharmazeutika
ATE399168T1 (de) Imidazopyridin-derivate und ihre verwendung als induzierbare no-synthase inhibitoren
NO20061344L (no) Imidazopyridinderivater som induserbare NO-syntaseoinhibitorer
SE0403086D0 (sv) Compounds
EA200700179A1 (ru) Производные пиррола, их получение и их применение в терапии
ATE419242T1 (de) Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
DE60325984D1 (de) 4-aminobenzofuranverbindungen als phosphodiesterase-4-inhibitoren
ATE471320T1 (de) 4-aminopiperidinderivate als inhibitoren der monoamin-aufnahme
ATE398617T1 (de) Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase
DE602004019698D1 (de) Morpholinderivate als inhibitoren der wiederaufnahme von norepinephrin

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties