ATE398617T1 - Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase - Google Patents

Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase

Info

Publication number
ATE398617T1
ATE398617T1 AT04787257T AT04787257T ATE398617T1 AT E398617 T1 ATE398617 T1 AT E398617T1 AT 04787257 T AT04787257 T AT 04787257T AT 04787257 T AT04787257 T AT 04787257T AT E398617 T1 ATE398617 T1 AT E398617T1
Authority
AT
Austria
Prior art keywords
inhibitors
imidazoä4
büpyridine
synthase
inducible
Prior art date
Application number
AT04787257T
Other languages
English (en)
Inventor
Thomas Fuchss
Rainer Boer
Wolf-Ruediger Ulrich
Manfrid Eltze
Degenhard Marx
Ulrich Graedler
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE398617T1 publication Critical patent/ATE398617T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
AT04787257T 2003-10-01 2004-09-30 Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase ATE398617T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03022042 2003-10-01

Publications (1)

Publication Number Publication Date
ATE398617T1 true ATE398617T1 (de) 2008-07-15

Family

ID=34384569

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04787257T ATE398617T1 (de) 2003-10-01 2004-09-30 Imidazoä4,5-büpyridinderivate als inhibitoren der induzierbaren no-synthase

Country Status (16)

Country Link
US (2) US7329677B2 (de)
EP (1) EP1675853B1 (de)
JP (1) JP2007507463A (de)
KR (1) KR20060092221A (de)
CN (1) CN1856492A (de)
AT (1) ATE398617T1 (de)
AU (1) AU2004276012A1 (de)
BR (1) BRPI0415038A (de)
CA (1) CA2540239A1 (de)
DE (1) DE602004014523D1 (de)
IL (1) IL173629A0 (de)
MX (1) MXPA06003347A (de)
NO (1) NO20061343L (de)
RS (1) RS20060205A (de)
WO (1) WO2005030768A1 (de)
ZA (1) ZA200601139B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7468377B2 (en) 2003-10-01 2008-12-23 Altana Pharma Ag Imidazopyridine-derivatives as inductible no-synthase inhibitors
EA200600601A1 (ru) 2003-10-01 2006-10-27 Алтана Фарма Аг Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
KR20060092297A (ko) 2003-10-01 2006-08-22 알타나 파마 아게 유도성 일산화질소 합성효소 억제제인 이미다조피리딘유도체
KR100863692B1 (ko) * 2006-12-08 2008-10-15 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린유도체
WO2009029625A1 (en) * 2007-08-27 2009-03-05 Kalypsys, Inc. 4- [heterocyclyl-methyl] -8-fluoro-quinolin-2-ones useful as nitric oxide synthase inhibitors
GB201512635D0 (en) 2015-07-17 2015-08-26 Ucl Business Plc Uses of therapeutic compounds

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
SE512835C2 (sv) 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
AUPP873799A0 (en) 1999-02-17 1999-03-11 Fujisawa Pharmaceutical Co., Ltd. Pyridine compounds
AU2003226706A1 (en) 2002-03-27 2003-10-08 Altana Pharma Ag Novel alkoxypyridine-derivatives
US7468377B2 (en) 2003-10-01 2008-12-23 Altana Pharma Ag Imidazopyridine-derivatives as inductible no-synthase inhibitors
JP2007507465A (ja) 2003-10-01 2007-03-29 アルタナ ファルマ アクチエンゲゼルシャフト 誘導性noシンターゼ阻害剤としてのイミダゾピリジン誘導体
EA200600601A1 (ru) 2003-10-01 2006-10-27 Алтана Фарма Аг Производные аминопиридина в качестве ингибиторов индуцируемой no-синтазы
KR20060092297A (ko) 2003-10-01 2006-08-22 알타나 파마 아게 유도성 일산화질소 합성효소 억제제인 이미다조피리딘유도체

Also Published As

Publication number Publication date
RS20060205A (en) 2008-08-07
US20080108652A1 (en) 2008-05-08
AU2004276012A1 (en) 2005-04-07
CN1856492A (zh) 2006-11-01
DE602004014523D1 (de) 2008-07-31
EP1675853B1 (de) 2008-06-18
JP2007507463A (ja) 2007-03-29
WO2005030768A1 (en) 2005-04-07
KR20060092221A (ko) 2006-08-22
ZA200601139B (en) 2007-05-30
NO20061343L (no) 2006-03-24
IL173629A0 (en) 2006-07-05
MXPA06003347A (es) 2006-06-08
CA2540239A1 (en) 2005-04-07
BRPI0415038A (pt) 2006-12-12
US20070010549A1 (en) 2007-01-11
US7329677B2 (en) 2008-02-12
EP1675853A1 (de) 2006-07-05

Similar Documents

Publication Publication Date Title
NO20061317L (no) Imidazopyridinderivater som induserbare NO-syntaseinhibatorer
ATE348616T1 (de) 2-hydroxy-6-phenylphenanthridine als pde-4-hemmer
ATE353217T1 (de) 3-hydroxy-6-phenylphenanthridine als pde-4 inhibitoren
BRPI0608886B8 (pt) derivados de n-sulfonilpirróis e seus usos
EA201270630A1 (ru) Гетероциклические сетр ингибиторы
EA200801366A1 (ru) Производные 3,6-дигидро-2-оксо-6н-1,3,4-тиадиазина
NO20061344L (no) Imidazopyridinderivater som induserbare NO-syntaseoinhibitorer
NO20061316L (no) Imidazopyndinderivater som induserbare NO-syntaseinhibitorer
DE60316984D1 (de) Benzoylsulfonamide als antitumor-mittel
SE0103710D0 (sv) Compounds
RS20060206A (en) Aminopyridine-derivatives as inducible no-synthase inhibitors
NO20061343L (no) Imidazo[4,5-b]pyridinderivater som induserbare NO-syntaseinhibitorer
ATE419242T1 (de) Pyrrolidinylharnstoffderivate als angiogeneseinhibitoren
ATE421505T1 (de) 4-aminobenzofuranverbindungen als phosphodiesterase-4-inhibitoren
ATE403422T1 (de) Substituierte hydrazone als hemmer von cyclooxygenase-2
ATE433975T1 (de) Als inos-inhibitoren geeignete imidazopyridinderivate
DE602004002464D1 (de) IMIDAZOi4,5-BöCHINOLINDERIVATE UND IHRE VERWENDUNG ALS INHIBITOREN DER INDUZIERBAREN NO-SYNTHASE
ATE374751T1 (de) 3,4-dihydro-1h-chinolin-2-onderivate als norepinephrin-wiederaufnahme-hemmern
GB0322750D0 (en) Organic compounds
ATE417040T1 (de) Nitratester von phenylaminothiophen- essigsäurederivaten
SE0004244D0 (sv) Novel compounds and their use

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties