ATE369140T1 - Stickstoffoxid zur behandlung therapieresistenter organismen - Google Patents

Stickstoffoxid zur behandlung therapieresistenter organismen

Info

Publication number
ATE369140T1
ATE369140T1 AT01965420T AT01965420T ATE369140T1 AT E369140 T1 ATE369140 T1 AT E369140T1 AT 01965420 T AT01965420 T AT 01965420T AT 01965420 T AT01965420 T AT 01965420T AT E369140 T1 ATE369140 T1 AT E369140T1
Authority
AT
Austria
Prior art keywords
therapy
treatment
nitrogen oxide
resistant organisms
resistant
Prior art date
Application number
AT01965420T
Other languages
English (en)
Inventor
Nigel Benjamin
Anthony Ormerod
Original Assignee
Univ Aberdeen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Aberdeen filed Critical Univ Aberdeen
Application granted granted Critical
Publication of ATE369140T1 publication Critical patent/ATE369140T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT01965420T 2000-09-08 2001-09-10 Stickstoffoxid zur behandlung therapieresistenter organismen ATE369140T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0022084.8A GB0022084D0 (en) 2000-09-08 2000-09-08 Treatment of multiply antibiotic-resistant organisms

Publications (1)

Publication Number Publication Date
ATE369140T1 true ATE369140T1 (de) 2007-08-15

Family

ID=9899110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01965420T ATE369140T1 (de) 2000-09-08 2001-09-10 Stickstoffoxid zur behandlung therapieresistenter organismen

Country Status (9)

Country Link
US (1) US20040037897A1 (de)
EP (1) EP1315509B1 (de)
JP (1) JP5634655B2 (de)
AT (1) ATE369140T1 (de)
AU (1) AU2001286064A1 (de)
DE (1) DE60129823T2 (de)
ES (1) ES2291345T3 (de)
GB (1) GB0022084D0 (de)
WO (1) WO2002020026A2 (de)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
EP1624953B1 (de) * 2003-04-23 2018-12-19 The University of Akron Sequestrierte reaktive materialien
CA2536827C (en) * 2003-07-09 2014-09-16 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
AU2005277397B2 (en) 2004-08-18 2011-08-25 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
DE602006006432D1 (de) * 2005-03-24 2009-06-04 Nolabs Ab Kosmetische behandlung mit stickoxid, vorrichtung zur durchführung dieser behandlung und herstellungsverfahren dafür
WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
CA2912259C (en) 2005-05-27 2020-04-28 Mark H. Schoenfisch Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
US7288622B1 (en) * 2006-09-19 2007-10-30 Issar Pharmaceuticals Pvt Ltd Composition for treatment of burns and wounds
GB0618711D0 (en) * 2006-09-22 2006-11-01 Univ Exeter Agricultural treatment
JP5172940B2 (ja) * 2007-03-27 2013-03-27 ノーラブズ エービー 一酸化窒素送達のための局所皮膚送達装置
KR101122469B1 (ko) * 2007-04-02 2012-07-12 파킨슨즈 인스티튜트 처치 치료의 부작용을 감소시키기 위한 방법 및 조성물
GB0715556D0 (en) * 2007-08-09 2007-09-19 Insense Ltd Improvements relating to skin dressings
US9278157B2 (en) 2007-08-09 2016-03-08 Insense Limited Nitric oxide-generating skin dressings
EP2209472A1 (de) 2007-10-12 2010-07-28 The University of North Carolina at Chapel Hill Verwendung von stickoxid zur verbesserung der wirksamkeit von silber und anderen topischen wundpflegemitteln
US20090130233A1 (en) * 2007-10-24 2009-05-21 Baker Christopher G Two part lotion
ES2715605T3 (es) 2007-11-21 2019-06-05 Smith & Nephew Apósito para heridas
ES2555204T3 (es) 2007-11-21 2015-12-29 T.J. Smith & Nephew Limited Dispositivo de succión y venda
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
CA2710349A1 (en) * 2007-12-27 2009-07-09 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide -donating compounds and uses thereof
JP5554723B2 (ja) 2008-01-28 2014-07-23 ゲノ エルエルシー 二酸化窒素（ｎｏ２）から一酸化窒素（ｎｏ）への変換
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
EP2334279A4 (de) * 2008-10-16 2013-03-20 Novan Inc Stickoxid freisetzende partikel für mundpflegeanwendungen
CA2740135A1 (en) * 2008-10-30 2010-05-06 Chris Miller Wound dressings comprising a nitric oxide gas producing component and an oxygen releasing component
US8568793B2 (en) * 2009-02-11 2013-10-29 Hope Medical Enterprises, Inc. Sodium nitrite-containing pharmaceutical compositions
US8613958B2 (en) 2009-06-22 2013-12-24 Geno Llc Nitric oxide therapies
US9526738B2 (en) 2009-08-21 2016-12-27 Novan, Inc. Topical gels and methods of using the same
CN102695528B (zh) 2009-08-21 2016-07-13 诺万公司 创伤敷料、其使用方法及其形成方法
EP2488591A1 (de) * 2009-10-13 2012-08-22 Novan, Inc. Stickoxidfreisetzende beschichtungen
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
JP6078472B2 (ja) 2010-11-25 2017-02-08 スミス アンド ネフュー ピーエルシーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ 組成物ｉ−ｉｉおよび生成物ならびにそれらの使用
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
ES2695173T3 (es) 2011-02-28 2019-01-02 Novan Inc Partículas de sílice modificadas con S-nitrosotiol que liberan óxido nítrico y procedimientos de fabricación de las mismas
WO2013006608A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Topical compositions
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
KR102428738B1 (ko) 2013-08-08 2022-08-02 노반, 인크. 국소 조성물 및 그의 사용 방법
KR102495101B1 (ko) 2014-07-11 2023-02-02 노반, 인크. 국소 항바이러스 조성물 및 그의 사용 방법
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
US10925689B2 (en) 2014-07-14 2021-02-23 Novan, Inc. Nitric oxide releasing nail coating compositions, nitric oxide releasing nail coatings, and methods of using the same
EP3177262A4 (de) 2014-08-08 2018-04-18 Novan Inc. Topische emulsionen
WO2017019614A1 (en) 2015-07-28 2017-02-02 Novan, Inc. Combinations and methods for the treatment and/or prevention of fungal infections
KR102363923B1 (ko) 2015-09-09 2022-02-21 어드밴스드 인헐레이션 테라피즈 (에이아이티) 리미티드 세기관지염이 있는 유아를 위한 산화질소 흡입 치료
EP3407900B1 (de) * 2016-01-27 2024-01-10 SYK Technologies, LLC Vorrichtung zur topischen anwendung von stickoxid und verfahren
US20190054038A1 (en) * 2016-02-25 2019-02-21 The Regents Of The University Of Michigan Nitric oxide generating formulations and kits
US10912743B2 (en) 2016-03-02 2021-02-09 Novan, Inc. Compositions for treating inflammation and methods of treating the same
BR112018070578A2 (pt) 2016-04-13 2019-02-12 Novan, Inc. composições, sistemas, kits, e métodos para tratar uma infecção
WO2019157295A1 (en) * 2018-02-09 2019-08-15 The Trustees Of Columbia University In The City Of New York Treating infections using inhibitor of cbb3-type oxidases
GB2579240B (en) * 2018-11-27 2020-12-16 Attgeno Ab New processes, compositions and medical uses
CA3142101A1 (en) 2019-06-04 2020-12-10 Thirty Holdings Limited Methods and compositions for generating nitric oxide and uses thereof
CA3142109A1 (en) 2019-06-04 2020-12-10 Thirty Respiratory Limited Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
JP2023526584A (ja) 2020-04-23 2023-06-22 サーティー レスピラトリー リミテッド Ｓａｒｓ－ｃｏｖ及びｓａｒｓ－ｃｏｖ－２の治療に使用するための一酸化窒素または一酸化窒素放出組成物
EP4138794A1 (de) 2020-04-23 2023-03-01 Thirty Respiratory Limited Verfahren und zusammensetzungen zur behandlung und bekämpfung von tuberkulose
GB202101543D0 (en) 2021-02-04 2021-03-24 Thirty Respiratory Ltd Vaping e-liquid composition and the use thereof
WO2023118839A1 (en) 2021-12-22 2023-06-29 Thirty Holdings Limited Powder composition
WO2023118841A2 (en) 2021-12-22 2023-06-29 Thirty Holdings Limited Powder composition

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3164617B2 (ja) * 1991-11-07 2001-05-08 株式会社日立製作所 文字図形変形処理装置および方法
US5664086A (en) * 1993-04-16 1997-09-02 Adobe Systems Incorporated Method and apparatus for generating digital type font, and resulting fonts using generic font and descriptor file
DE69532921T2 (de) * 1994-02-21 2005-04-14 Aberdeen University, Aberdeen Angesäuertes nitrit zur verwendung als antimikrobielles mittel
US6426066B1 (en) * 2000-01-12 2002-07-30 California Pacific Labs, Inc. Use of physiologically balanced, ionized, acidic solution in wound healing
CA2402520A1 (en) * 2000-03-13 2001-09-20 Kenneth Beckman Biocidal methods and compositions

Also Published As

Publication number Publication date
WO2002020026A3 (en) 2002-05-16
GB0022084D0 (en) 2000-10-25
WO2002020026A2 (en) 2002-03-14
EP1315509B1 (de) 2007-08-08
DE60129823T2 (de) 2008-04-24
DE60129823D1 (de) 2007-09-20
ES2291345T3 (es) 2008-03-01
US20040037897A1 (en) 2004-02-26
JP5634655B2 (ja) 2014-12-03
AU2001286064A1 (en) 2002-03-22
JP2004508337A (ja) 2004-03-18
EP1315509A2 (de) 2003-06-04

Similar Documents

Publication Publication Date Title
ATE369140T1 (de) Stickstoffoxid zur behandlung therapieresistenter organismen
NO20061736L (no) Krystallform av epotilon B
DE602005012276D1 (de) Verwendung von probiotischen bakterien zur herstellung von topischen zusammensetzungen zum schutz der haut
PT1206474E (pt) Compostos de sulfonilfenilpirazole uteis como inibidores de cox-2
ATE440132T1 (de) Bacillus subtilis zur verwendung gegen tierische und menschliche krankheitserreger
NO20050210L (no) Antibakterielle amid-makrocykluser
CY1108107T1 (el) Μικροοργανισμος για βιολογικη αποτοξικοποιηση μυκοτοξινων, συγκεκριμενα ωχρατοξινων και/ή ζεαραλενονων, καθως και σχετικη μεθοδος και χρηση
DE60136826D1 (de) Verwendung von asiatsäure oder asiaticosid zur behandlung von krebs
TW200716162A (en) Use of bovine lactoferrin in the manufacture of a medicament for inhibiting the growth of bacteria
DE60225590D1 (de) C-kithemmer zur behandlung von bakteriellen infektionen
AU2889201A (en) Automatic water toxicity measuring apparatus
ATE549023T1 (de) Formulierungen mit jorumycin-, renieramycin-, safracin- oder saframycin-verwandten verbindungen und einen disaccharide zur behandlung von proliferativen erkrankungen
DE602004022689D1 (de) Verwendung probiotischer bakterien zur behandlung von infektionen
HK1106253A1 (en) Desoxo-nonadepsipeptides
UA89800C2 (en) Acylated nonadepsipeptides used as lysobactin derivatives
DE502005008925D1 (de) Substituierte nonadepsipeptide
MXPA05011830A (es) Peptidos para uso en el tratamiento de la obesidad.
MX2008016269A (es) Fermentacion y purificacion de cromoproteinas actinomadura y especies relacionadas.
CY1110156T1 (el) Υποκατεστημενες ενωσεις 4,5,6,7-τετραϋδρο-βενζοθειαζολ-2-υλαμινης
BR0309526A (pt) Metiltiofenocarboxanilidas
DE10342518A1 (de) Plasminogen-Aktivatoren mit verringerter Lysin-Bindungskapazität
RS20110079A (en) MICROBIOLOGICAL PROCEDURE FOR THE PREPARATION OF 7ALFA-SUBSTITUTED 11ALFA-HYDROXYSTEROIDS
ATE328602T1 (de) Kombinationspräparat zur behandlung des diabetes mellitus
PL1687014T3 (pl) Zastosowanie dodatkowo przefermentowanego wywaru zbożowego do zapobiegania i/lub leczenia podwyższonych wartości cukru we krwi
ATE423780T1 (de) Makrozyclen zur behandlung von krebserkrankungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1315509

Country of ref document: EP

REN Ceased due to non-payment of the annual fee